Step-stress model using logistic regression model and its application in medicine

A linear logistic model is proposed for estimating the probability of survival to a specified stage using a step-stress model. Parameter estimates may be obtained numerically for the general case of the k-step model, and explicit solutions are given in the case of the two-step stress model. Of speci...

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Bibliographic Details
Main Authors: Jamal Ibrahim, Daoud, Khamis, Imad
Format: Article
Language:English
Published: Pushpa Publishing House 2010
Subjects:
Online Access:http://irep.iium.edu.my/3973/
http://irep.iium.edu.my/3973/
http://irep.iium.edu.my/3973/1/Step-stress_Model_using_Logistic.pdf
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Summary:A linear logistic model is proposed for estimating the probability of survival to a specified stage using a step-stress model. Parameter estimates may be obtained numerically for the general case of the k-step model, and explicit solutions are given in the case of the two-step stress model. Of special interest to us is the application of this model to the prediction of mortality in HIV-1 infected individuals that based on clinical of Centers for Disease Control and Prevention clinical stage of disease (A, B and C stages). © 2010 Pushpa Publishing House.