Morbidity and mortality associated with tumour-related hindquarter amputation: a review of 23 cases

Background: Hindquarter amputation, the removal of the entire lower limb along with the ipsilateral pelvic bone, is reserved for malignant or aggressive tumours located in the proximal lower extremity. With the advancement in limb salvage surgery (LSS), it is reserved for palliative surgery or when...

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Main Authors:	Sharifudin, Mohd Ariff, Wan Ismail, Wan Faisham Numan, Wan, Zulmi, Mat Zin, Nor Azman, Mohamed Amin, Mohamed Azril, Goh, Kian Liang
Format:	Conference or Workshop Item
Language:	English English
Published:	2014
Subjects:	RC0254 Neoplasms. Tumors. Oncology (including Cancer) RD701 Orthopedics RD92 Wounds and injuries
Online Access:	http://irep.iium.edu.my/39542/ http://irep.iium.edu.my/39542/ http://irep.iium.edu.my/39542/1/Program_and_Abstract_Book_-_HINDQUARTER_AMPUTATION.pdf http://irep.iium.edu.my/39542/2/IHCIIUM_2014_-_ORAL_-_HEMIPELVECTOMY.pdf

id	iium-39542
recordtype	eprints
spelling	iium-395422018-12-20T00:22:43Z http://irep.iium.edu.my/39542/ Morbidity and mortality associated with tumour-related hindquarter amputation: a review of 23 cases Sharifudin, Mohd Ariff Wan Ismail, Wan Faisham Numan Wan, Zulmi Mat Zin, Nor Azman Mohamed Amin, Mohamed Azril Goh, Kian Liang RC0254 Neoplasms. Tumors. Oncology (including Cancer) RD701 Orthopedics RD92 Wounds and injuries Background: Hindquarter amputation, the removal of the entire lower limb along with the ipsilateral pelvic bone, is reserved for malignant or aggressive tumours located in the proximal lower extremity. With the advancement in limb salvage surgery (LSS), it is reserved for palliative surgery or when LSS is contraindicated. This report aims to review the morbidity and mortality associated with this procedure in the treatment of pelvic bone and soft tissue tumours. Methodology: Patients with bone or soft tissue tumour involving the pelvis who underwent hindquarter amputation at any point in their clinical course between year 2000 and 2010 were reviewed. Patients were recruited from a single oncology referral institution. Results: Twenty-three patients were included in this review, consisted of 17 males and 6 females with mean age of 40.1 (range 8 to 79 years old). Ten patients underwent surgery for palliation. Classical type of pelvic resection was performed on 11 patients while others were subjected for modified (6), extended (5) and compound (1) type. Commonest underlying pathology was pelvic osteosarcoma (5 patients). Majority of wounds (47.8%) were primarily closed with posterior myocutaneous flap. There was one perioperative death due to sepsis with lung complications. The average follow-up was 13 months (range 2 to 109 months). Eight patients were still alive on their last follow-up, 9 died due to advanced stage of disease, while 3 died of other causes. Commonest complications observed were wound-related. All patients had poor functional outcome on their recent follow-up. Conclusion: Hindquarter amputation remains an important option with considerable morbidity and is indicated for only minority of far-advanced tumours. It offers a chance of palliation and possibly cure when lesser surgical options have been exhausted. 2014 Conference or Workshop Item PeerReviewed application/pdf en http://irep.iium.edu.my/39542/1/Program_and_Abstract_Book_-_HINDQUARTER_AMPUTATION.pdf application/pdf en http://irep.iium.edu.my/39542/2/IHCIIUM_2014_-_ORAL_-_HEMIPELVECTOMY.pdf Sharifudin, Mohd Ariff and Wan Ismail, Wan Faisham Numan and Wan, Zulmi and Mat Zin, Nor Azman and Mohamed Amin, Mohamed Azril and Goh, Kian Liang (2014) Morbidity and mortality associated with tumour-related hindquarter amputation: a review of 23 cases. In: International Health Conference IIUM 2014, 3-4 Dec 2014, Kuantan, Pahang. http://www.iium.edu.my/ihci/
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English English
topic	RC0254 Neoplasms. Tumors. Oncology (including Cancer) RD701 Orthopedics RD92 Wounds and injuries
spellingShingle	RC0254 Neoplasms. Tumors. Oncology (including Cancer) RD701 Orthopedics RD92 Wounds and injuries Sharifudin, Mohd Ariff Wan Ismail, Wan Faisham Numan Wan, Zulmi Mat Zin, Nor Azman Mohamed Amin, Mohamed Azril Goh, Kian Liang Morbidity and mortality associated with tumour-related hindquarter amputation: a review of 23 cases
description	Background: Hindquarter amputation, the removal of the entire lower limb along with the ipsilateral pelvic bone, is reserved for malignant or aggressive tumours located in the proximal lower extremity. With the advancement in limb salvage surgery (LSS), it is reserved for palliative surgery or when LSS is contraindicated. This report aims to review the morbidity and mortality associated with this procedure in the treatment of pelvic bone and soft tissue tumours. Methodology: Patients with bone or soft tissue tumour involving the pelvis who underwent hindquarter amputation at any point in their clinical course between year 2000 and 2010 were reviewed. Patients were recruited from a single oncology referral institution. Results: Twenty-three patients were included in this review, consisted of 17 males and 6 females with mean age of 40.1 (range 8 to 79 years old). Ten patients underwent surgery for palliation. Classical type of pelvic resection was performed on 11 patients while others were subjected for modified (6), extended (5) and compound (1) type. Commonest underlying pathology was pelvic osteosarcoma (5 patients). Majority of wounds (47.8%) were primarily closed with posterior myocutaneous flap. There was one perioperative death due to sepsis with lung complications. The average follow-up was 13 months (range 2 to 109 months). Eight patients were still alive on their last follow-up, 9 died due to advanced stage of disease, while 3 died of other causes. Commonest complications observed were wound-related. All patients had poor functional outcome on their recent follow-up. Conclusion: Hindquarter amputation remains an important option with considerable morbidity and is indicated for only minority of far-advanced tumours. It offers a chance of palliation and possibly cure when lesser surgical options have been exhausted.
format	Conference or Workshop Item
author	Sharifudin, Mohd Ariff Wan Ismail, Wan Faisham Numan Wan, Zulmi Mat Zin, Nor Azman Mohamed Amin, Mohamed Azril Goh, Kian Liang
author_facet	Sharifudin, Mohd Ariff Wan Ismail, Wan Faisham Numan Wan, Zulmi Mat Zin, Nor Azman Mohamed Amin, Mohamed Azril Goh, Kian Liang
author_sort	Sharifudin, Mohd Ariff
title	Morbidity and mortality associated with tumour-related hindquarter amputation: a review of 23 cases
title_short	Morbidity and mortality associated with tumour-related hindquarter amputation: a review of 23 cases
title_full	Morbidity and mortality associated with tumour-related hindquarter amputation: a review of 23 cases
title_fullStr	Morbidity and mortality associated with tumour-related hindquarter amputation: a review of 23 cases
title_full_unstemmed	Morbidity and mortality associated with tumour-related hindquarter amputation: a review of 23 cases
title_sort	morbidity and mortality associated with tumour-related hindquarter amputation: a review of 23 cases
publishDate	2014
url	http://irep.iium.edu.my/39542/ http://irep.iium.edu.my/39542/ http://irep.iium.edu.my/39542/1/Program_and_Abstract_Book_-_HINDQUARTER_AMPUTATION.pdf http://irep.iium.edu.my/39542/2/IHCIIUM_2014_-_ORAL_-_HEMIPELVECTOMY.pdf
first_indexed	2023-09-18T20:56:50Z
last_indexed	2023-09-18T20:56:50Z
_version_	1777410360006934528

Morbidity and mortality associated with tumour-related hindquarter amputation: a review of 23 cases

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