Antibacterial efficacy of the seed extracts of Melia azedarach against some hospital isolated human pathogenic bacterial strains

Objective: To investigate the antibacterial potential of the polar and non-polar extracts of the seeds of Melia azedarach (M. azedarach) L. (Meliaceae) against eighteen hospital isolated human pathogenic bacterial strains. Methods: Petrol, benzene, ethyl acetate, methanol, and aqueous extracts at fi...

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Main Author: Ahmed, Qamar Uddin
Format: Article
Language:English
Published: Asian Pacific Journal of Tropical Biomedicine 2011
Subjects:
Online Access:http://irep.iium.edu.my/3930/
http://irep.iium.edu.my/3930/
http://irep.iium.edu.my/3930/
http://irep.iium.edu.my/3930/1/Antibacterial_efficacy_of_the_seed_extracts_of_Melia_azedarach_against.pdf
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spelling iium-39302013-06-26T01:29:29Z http://irep.iium.edu.my/3930/ Antibacterial efficacy of the seed extracts of Melia azedarach against some hospital isolated human pathogenic bacterial strains Ahmed, Qamar Uddin QD Chemistry QK Botany Objective: To investigate the antibacterial potential of the polar and non-polar extracts of the seeds of Melia azedarach (M. azedarach) L. (Meliaceae) against eighteen hospital isolated human pathogenic bacterial strains. Methods: Petrol, benzene, ethyl acetate, methanol, and aqueous extracts at five different concentrations (1, 2, 5, 10 and 15 mg/mL) were evaluated. Disk diffusion method was followed to evaluate the antibacterial efficacy. Results: All extracts of the seeds demonstrated significant antibacterial activity against tested pathogens. Among all extracts, ethyl acetate extract revealed the highest inhibition comparatively. The present study also favored the traditional uses reported earlier. Conclusions: Results of this study strongly confirm that the seed extracts of M. azedarach could be effective antibiotics, both in controlling gram-positive and gram-negative human pathogenic infections. Asian Pacific Journal of Tropical Biomedicine 2011-05-20 Article PeerReviewed application/pdf en cc_by_nc http://irep.iium.edu.my/3930/1/Antibacterial_efficacy_of_the_seed_extracts_of_Melia_azedarach_against.pdf Ahmed, Qamar Uddin (2011) Antibacterial efficacy of the seed extracts of Melia azedarach against some hospital isolated human pathogenic bacterial strains. Asian Pacific Journal of Tropical Biomedicine, 1 (1). pp. 452-455. ISSN 2221 1691 http://www.elsevier.com/locate/apjtb doi:10.1016/S2221-1691(11)60099-3
repository_type Digital Repository
institution_category Local University
institution International Islamic University Malaysia
building IIUM Repository
collection Online Access
language English
topic QD Chemistry
QK Botany
spellingShingle QD Chemistry
QK Botany
Ahmed, Qamar Uddin
Antibacterial efficacy of the seed extracts of Melia azedarach against some hospital isolated human pathogenic bacterial strains
description Objective: To investigate the antibacterial potential of the polar and non-polar extracts of the seeds of Melia azedarach (M. azedarach) L. (Meliaceae) against eighteen hospital isolated human pathogenic bacterial strains. Methods: Petrol, benzene, ethyl acetate, methanol, and aqueous extracts at five different concentrations (1, 2, 5, 10 and 15 mg/mL) were evaluated. Disk diffusion method was followed to evaluate the antibacterial efficacy. Results: All extracts of the seeds demonstrated significant antibacterial activity against tested pathogens. Among all extracts, ethyl acetate extract revealed the highest inhibition comparatively. The present study also favored the traditional uses reported earlier. Conclusions: Results of this study strongly confirm that the seed extracts of M. azedarach could be effective antibiotics, both in controlling gram-positive and gram-negative human pathogenic infections.
format Article
author Ahmed, Qamar Uddin
author_facet Ahmed, Qamar Uddin
author_sort Ahmed, Qamar Uddin
title Antibacterial efficacy of the seed extracts of Melia azedarach against some hospital isolated human pathogenic bacterial strains
title_short Antibacterial efficacy of the seed extracts of Melia azedarach against some hospital isolated human pathogenic bacterial strains
title_full Antibacterial efficacy of the seed extracts of Melia azedarach against some hospital isolated human pathogenic bacterial strains
title_fullStr Antibacterial efficacy of the seed extracts of Melia azedarach against some hospital isolated human pathogenic bacterial strains
title_full_unstemmed Antibacterial efficacy of the seed extracts of Melia azedarach against some hospital isolated human pathogenic bacterial strains
title_sort antibacterial efficacy of the seed extracts of melia azedarach against some hospital isolated human pathogenic bacterial strains
publisher Asian Pacific Journal of Tropical Biomedicine
publishDate 2011
url http://irep.iium.edu.my/3930/
http://irep.iium.edu.my/3930/
http://irep.iium.edu.my/3930/
http://irep.iium.edu.my/3930/1/Antibacterial_efficacy_of_the_seed_extracts_of_Melia_azedarach_against.pdf
first_indexed 2023-09-18T20:11:55Z
last_indexed 2023-09-18T20:11:55Z
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