Study on anti-bacterial potentials of some Malaysian brown seaweeds

With increasing in emergence of resistance pathogenic microorganisms to majority of antibiotics, there is an urgent and continuous need for exploring and developing cheaper and effective plant based drugs with better bioactive potential and least side effects. Bioactive extracts from four species...

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Main Authors:	Jaswir, Irwandi, Tawakalit Tope, Asiyanbi-Hammed, Ahmad Raus, Raha, A. Monsur, Hammed Ademola, Ramli, Nazaruddin
Format:	Article
Language:	English English English
Published:	Elsevier Inc. 2014
Subjects:	TP Chemical technology TP248.13 Biotechnology
Online Access:	http://irep.iium.edu.my/39291/ http://irep.iium.edu.my/39291/ http://irep.iium.edu.my/39291/ http://irep.iium.edu.my/39291/1/Study_on_anti_bacterial.pdf http://irep.iium.edu.my/39291/4/39291_Study_on_anti-bacterial_potentials_WOS.pdf http://irep.iium.edu.my/39291/5/39291_Study_on_anti-bacterial_potentials_SCOPUS.pdf

id	iium-39291
recordtype	eprints
spelling	iium-392912018-05-23T05:47:54Z http://irep.iium.edu.my/39291/ Study on anti-bacterial potentials of some Malaysian brown seaweeds Jaswir, Irwandi Tawakalit Tope, Asiyanbi-Hammed Ahmad Raus, Raha A. Monsur, Hammed Ademola Ramli, Nazaruddin TP Chemical technology TP248.13 Biotechnology With increasing in emergence of resistance pathogenic microorganisms to majority of antibiotics, there is an urgent and continuous need for exploring and developing cheaper and effective plant based drugs with better bioactive potential and least side effects. Bioactive extracts from four species of brown seaweeds (Sargassum plagyophillum, Sargassum flavellum, Padina australis and Sargassum binderi) of Malaysia origin were tested in vitro for their anti-bacterial activities against gram positive bacteria (Bacillus subtilis and Staphylococcus aureus) and gram negative bacteria (Pseudomonas aeruginosa and Escherichia coli). Four solvents (methanol, acetone, ethyl acetate and chloroform) were used during the preliminary screening stage to obtain crude extracts. None of the crude extracts displayed antimicrobial activity against the gram negative bacteria while the gram positive bacteria were inhibited. Methanol extract of S. plagyophillum was the best in terms of yield (4.72%) and antimicrobial activity with inhibition zone of 12 mm against B. subtilis. Chloroform fraction gave highest inhibition zone of 17 mm against B. subtilis. Hence, the result from this work showed that S. plagyophillum has the potential for antimicrobial drug production. Elsevier Inc. 2014-12-05 Article PeerReviewed application/pdf en http://irep.iium.edu.my/39291/1/Study_on_anti_bacterial.pdf application/pdf en http://irep.iium.edu.my/39291/4/39291_Study_on_anti-bacterial_potentials_WOS.pdf application/pdf en http://irep.iium.edu.my/39291/5/39291_Study_on_anti-bacterial_potentials_SCOPUS.pdf Jaswir, Irwandi and Tawakalit Tope, Asiyanbi-Hammed and Ahmad Raus, Raha and A. Monsur, Hammed Ademola and Ramli, Nazaruddin (2014) Study on anti-bacterial potentials of some Malaysian brown seaweeds. Food Hydrocolloids, 42 (P2). pp. 275-279. ISSN 0268-005X http://www.sciencedirect.com/science/article/pii/S0268005X14000812 10.1016/j.foodhyd.2014.03.008
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English English English
topic	TP Chemical technology TP248.13 Biotechnology
spellingShingle	TP Chemical technology TP248.13 Biotechnology Jaswir, Irwandi Tawakalit Tope, Asiyanbi-Hammed Ahmad Raus, Raha A. Monsur, Hammed Ademola Ramli, Nazaruddin Study on anti-bacterial potentials of some Malaysian brown seaweeds
description	With increasing in emergence of resistance pathogenic microorganisms to majority of antibiotics, there is an urgent and continuous need for exploring and developing cheaper and effective plant based drugs with better bioactive potential and least side effects. Bioactive extracts from four species of brown seaweeds (Sargassum plagyophillum, Sargassum flavellum, Padina australis and Sargassum binderi) of Malaysia origin were tested in vitro for their anti-bacterial activities against gram positive bacteria (Bacillus subtilis and Staphylococcus aureus) and gram negative bacteria (Pseudomonas aeruginosa and Escherichia coli). Four solvents (methanol, acetone, ethyl acetate and chloroform) were used during the preliminary screening stage to obtain crude extracts. None of the crude extracts displayed antimicrobial activity against the gram negative bacteria while the gram positive bacteria were inhibited. Methanol extract of S. plagyophillum was the best in terms of yield (4.72%) and antimicrobial activity with inhibition zone of 12 mm against B. subtilis. Chloroform fraction gave highest inhibition zone of 17 mm against B. subtilis. Hence, the result from this work showed that S. plagyophillum has the potential for antimicrobial drug production.
format	Article
author	Jaswir, Irwandi Tawakalit Tope, Asiyanbi-Hammed Ahmad Raus, Raha A. Monsur, Hammed Ademola Ramli, Nazaruddin
author_facet	Jaswir, Irwandi Tawakalit Tope, Asiyanbi-Hammed Ahmad Raus, Raha A. Monsur, Hammed Ademola Ramli, Nazaruddin
author_sort	Jaswir, Irwandi
title	Study on anti-bacterial potentials of some Malaysian brown seaweeds
title_short	Study on anti-bacterial potentials of some Malaysian brown seaweeds
title_full	Study on anti-bacterial potentials of some Malaysian brown seaweeds
title_fullStr	Study on anti-bacterial potentials of some Malaysian brown seaweeds
title_full_unstemmed	Study on anti-bacterial potentials of some Malaysian brown seaweeds
title_sort	study on anti-bacterial potentials of some malaysian brown seaweeds
publisher	Elsevier Inc.
publishDate	2014
url	http://irep.iium.edu.my/39291/ http://irep.iium.edu.my/39291/ http://irep.iium.edu.my/39291/ http://irep.iium.edu.my/39291/1/Study_on_anti_bacterial.pdf http://irep.iium.edu.my/39291/4/39291_Study_on_anti-bacterial_potentials_WOS.pdf http://irep.iium.edu.my/39291/5/39291_Study_on_anti-bacterial_potentials_SCOPUS.pdf
first_indexed	2023-09-18T20:56:26Z
last_indexed	2023-09-18T20:56:26Z
_version_	1777410335022514176

Study on anti-bacterial potentials of some Malaysian brown seaweeds

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