Acute kidney injury (AKI) in the intensive care unit (ICU) of Hospital Tengku Ampuan Afzan Kuantan (HTAA): Incidence, risk factors and outcome

Introduction: AKI is common and carries a high mortality rate. Most epidemiological studies were retrospective and were done in Western populations. A prospective study in a non-European population utilising the recent AKI consensus guideline is warranted. We aim to assess the AKI epidemiology in ou...

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Main Authors:	Md Ralib, Azrina, Mat Nor, Mohd. Basri
Format:	Conference or Workshop Item
Language:	English
Published:	2014
Subjects:	R Medicine (General)
Online Access:	http://irep.iium.edu.my/39176/ http://irep.iium.edu.my/39176/1/NCCRirep.pdf

id	iium-39176
recordtype	eprints
spelling	iium-391762014-11-18T01:17:16Z http://irep.iium.edu.my/39176/ Acute kidney injury (AKI) in the intensive care unit (ICU) of Hospital Tengku Ampuan Afzan Kuantan (HTAA): Incidence, risk factors and outcome Md Ralib, Azrina Mat Nor, Mohd. Basri R Medicine (General) Introduction: AKI is common and carries a high mortality rate. Most epidemiological studies were retrospective and were done in Western populations. A prospective study in a non-European population utilising the recent AKI consensus guideline is warranted. We aim to assess the AKI epidemiology in our local ICU. This will be the basis of future multicenter trial, and could provide data for the design of future trials. Methodology: This was a single centre, prospective observational study at the ICU of HTAA. The study was registered under the Malaysian NMRR and approved by the IIUM Ethics Committee (IREC 266). All patients more than 18 years being admitted to ICU and stayed for more than 48 hours were included in the study. Results: A total of 134 patients were recruited. 72 patients (54%) had AKI. 54 (40%) had a composite outcome of death or dialysis. Patients with AKI had longer duration of ICU stay (9.5+10.3 vs 6.3+5.5days,p=0.03). Those with AKI were also more likely to die or needed dialysis in 30 days compared to those without AKI (55.6% vs 21.7%, p<0.001). Of those with AKI, 42% were Stage 2 and 58% were Stage 3. Increasing stages of AKI is associated with increasing rate of death or dialysis. Discussion/Conclusion: AKI is common in our ICU, and is associated with higher morbidity and mortality. Of those with AKI, almost all presented with higher stages of AKI. None presented with Stage 1 AKI. This may reflect late presentation of illness on ICU admission in our population. 2014 Conference or Workshop Item NonPeerReviewed application/pdf en http://irep.iium.edu.my/39176/1/NCCRirep.pdf Md Ralib, Azrina and Mat Nor, Mohd. Basri (2014) Acute kidney injury (AKI) in the intensive care unit (ICU) of Hospital Tengku Ampuan Afzan Kuantan (HTAA): Incidence, risk factors and outcome. In: 8th National Conference for Clinical Research 2014, 30th-2nd October 2014, Kuching, Sarawak. (Unpublished)
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English
topic	R Medicine (General)
spellingShingle	R Medicine (General) Md Ralib, Azrina Mat Nor, Mohd. Basri Acute kidney injury (AKI) in the intensive care unit (ICU) of Hospital Tengku Ampuan Afzan Kuantan (HTAA): Incidence, risk factors and outcome
description	Introduction: AKI is common and carries a high mortality rate. Most epidemiological studies were retrospective and were done in Western populations. A prospective study in a non-European population utilising the recent AKI consensus guideline is warranted. We aim to assess the AKI epidemiology in our local ICU. This will be the basis of future multicenter trial, and could provide data for the design of future trials. Methodology: This was a single centre, prospective observational study at the ICU of HTAA. The study was registered under the Malaysian NMRR and approved by the IIUM Ethics Committee (IREC 266). All patients more than 18 years being admitted to ICU and stayed for more than 48 hours were included in the study. Results: A total of 134 patients were recruited. 72 patients (54%) had AKI. 54 (40%) had a composite outcome of death or dialysis. Patients with AKI had longer duration of ICU stay (9.5+10.3 vs 6.3+5.5days,p=0.03). Those with AKI were also more likely to die or needed dialysis in 30 days compared to those without AKI (55.6% vs 21.7%, p<0.001). Of those with AKI, 42% were Stage 2 and 58% were Stage 3. Increasing stages of AKI is associated with increasing rate of death or dialysis. Discussion/Conclusion: AKI is common in our ICU, and is associated with higher morbidity and mortality. Of those with AKI, almost all presented with higher stages of AKI. None presented with Stage 1 AKI. This may reflect late presentation of illness on ICU admission in our population.
format	Conference or Workshop Item
author	Md Ralib, Azrina Mat Nor, Mohd. Basri
author_facet	Md Ralib, Azrina Mat Nor, Mohd. Basri
author_sort	Md Ralib, Azrina
title	Acute kidney injury (AKI) in the intensive care unit (ICU) of Hospital Tengku Ampuan Afzan Kuantan (HTAA): Incidence, risk factors and outcome
title_short	Acute kidney injury (AKI) in the intensive care unit (ICU) of Hospital Tengku Ampuan Afzan Kuantan (HTAA): Incidence, risk factors and outcome
title_full	Acute kidney injury (AKI) in the intensive care unit (ICU) of Hospital Tengku Ampuan Afzan Kuantan (HTAA): Incidence, risk factors and outcome
title_fullStr	Acute kidney injury (AKI) in the intensive care unit (ICU) of Hospital Tengku Ampuan Afzan Kuantan (HTAA): Incidence, risk factors and outcome
title_full_unstemmed	Acute kidney injury (AKI) in the intensive care unit (ICU) of Hospital Tengku Ampuan Afzan Kuantan (HTAA): Incidence, risk factors and outcome
title_sort	acute kidney injury (aki) in the intensive care unit (icu) of hospital tengku ampuan afzan kuantan (htaa): incidence, risk factors and outcome
publishDate	2014
url	http://irep.iium.edu.my/39176/ http://irep.iium.edu.my/39176/1/NCCRirep.pdf
first_indexed	2023-09-18T20:56:16Z
last_indexed	2023-09-18T20:56:16Z
_version_	1777410325106130944

Acute kidney injury (AKI) in the intensive care unit (ICU) of Hospital Tengku Ampuan Afzan Kuantan (HTAA): Incidence, risk factors and outcome

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