Impact of thymoquinone supplementation on immobilisation stress-induced changes in reproductive characteristics of male mice

The aim of the current study was to investigate changes in the reproductive parameters during stress and the impact of thymoquinone during the period. The effects of stress were measured through immobilisation stress on mice. Group I was administered normal saline daily via intraperitoneal injection...

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Main Authors:	Abdul Rahman, Suzanah, Mohamed Anwar, Norul Athirah, Shaik , Sadak Basha, Kamarzaman, Saheera
Format:	Article
Language:	English
Published:	Applied and Natural Science Foundation 2014
Subjects:	QP Physiology R Medicine (General)
Online Access:	http://irep.iium.edu.my/39098/ http://irep.iium.edu.my/39098/ http://irep.iium.edu.my/39098/1/JANS-Suzanah.pdf

id	iium-39098
recordtype	eprints
spelling	iium-390982015-08-31T17:59:17Z http://irep.iium.edu.my/39098/ Impact of thymoquinone supplementation on immobilisation stress-induced changes in reproductive characteristics of male mice Abdul Rahman, Suzanah Mohamed Anwar, Norul Athirah Shaik , Sadak Basha Kamarzaman, Saheera QP Physiology R Medicine (General) The aim of the current study was to investigate changes in the reproductive parameters during stress and the impact of thymoquinone during the period. The effects of stress were measured through immobilisation stress on mice. Group I was administered normal saline daily via intraperitoneal injection while Groups II and III were subjected to 2 and 6 hours of immobilisation stress respectively. Groups IV and V were subjected to stress for 2 and 6 hours respectively followed by intraperitoneal injection of 10 mg/kg thymoquinone which was continued on alternate days. The level of significance was set at p<0.05 and statistical analysis showed significant difference in testicular weight of mice in groups II and III compared to the controls but no significant difference was obtained for sperm count between all groups. Sperm motility, however, was significantly different among the groups under stress for 2 and 6 hours and that of 6 hours with the treatment of thymoquinone when compared to the controls. The histology of the testes also indicated a few alterations in comparison to the controls in the germinal epithelium and spermatogenic pattern in groups III and V. Applied and Natural Science Foundation 2014 Article PeerReviewed application/pdf en http://irep.iium.edu.my/39098/1/JANS-Suzanah.pdf Abdul Rahman, Suzanah and Mohamed Anwar, Norul Athirah and Shaik , Sadak Basha and Kamarzaman, Saheera (2014) Impact of thymoquinone supplementation on immobilisation stress-induced changes in reproductive characteristics of male mice. Journal of Applied and Natural Science, 6 (1). pp. 1-5. ISSN 0974-9411 (P); 2231-5209 (O) http://www.ansfoundation.org/abstract/abstract611
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English
topic	QP Physiology R Medicine (General)
spellingShingle	QP Physiology R Medicine (General) Abdul Rahman, Suzanah Mohamed Anwar, Norul Athirah Shaik , Sadak Basha Kamarzaman, Saheera Impact of thymoquinone supplementation on immobilisation stress-induced changes in reproductive characteristics of male mice
description	The aim of the current study was to investigate changes in the reproductive parameters during stress and the impact of thymoquinone during the period. The effects of stress were measured through immobilisation stress on mice. Group I was administered normal saline daily via intraperitoneal injection while Groups II and III were subjected to 2 and 6 hours of immobilisation stress respectively. Groups IV and V were subjected to stress for 2 and 6 hours respectively followed by intraperitoneal injection of 10 mg/kg thymoquinone which was continued on alternate days. The level of significance was set at p<0.05 and statistical analysis showed significant difference in testicular weight of mice in groups II and III compared to the controls but no significant difference was obtained for sperm count between all groups. Sperm motility, however, was significantly different among the groups under stress for 2 and 6 hours and that of 6 hours with the treatment of thymoquinone when compared to the controls. The histology of the testes also indicated a few alterations in comparison to the controls in the germinal epithelium and spermatogenic pattern in groups III and V.
format	Article
author	Abdul Rahman, Suzanah Mohamed Anwar, Norul Athirah Shaik , Sadak Basha Kamarzaman, Saheera
author_facet	Abdul Rahman, Suzanah Mohamed Anwar, Norul Athirah Shaik , Sadak Basha Kamarzaman, Saheera
author_sort	Abdul Rahman, Suzanah
title	Impact of thymoquinone supplementation on immobilisation stress-induced changes in reproductive characteristics of male mice
title_short	Impact of thymoquinone supplementation on immobilisation stress-induced changes in reproductive characteristics of male mice
title_full	Impact of thymoquinone supplementation on immobilisation stress-induced changes in reproductive characteristics of male mice
title_fullStr	Impact of thymoquinone supplementation on immobilisation stress-induced changes in reproductive characteristics of male mice
title_full_unstemmed	Impact of thymoquinone supplementation on immobilisation stress-induced changes in reproductive characteristics of male mice
title_sort	impact of thymoquinone supplementation on immobilisation stress-induced changes in reproductive characteristics of male mice
publisher	Applied and Natural Science Foundation
publishDate	2014
url	http://irep.iium.edu.my/39098/ http://irep.iium.edu.my/39098/ http://irep.iium.edu.my/39098/1/JANS-Suzanah.pdf
first_indexed	2023-09-18T20:56:10Z
last_indexed	2023-09-18T20:56:10Z
_version_	1777410318564065280

Impact of thymoquinone supplementation on immobilisation stress-induced changes in reproductive characteristics of male mice

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