Changes in the markers of atherosclerosis following administration of Belimbing dayak (Baccaurea angulata) fruit juice in experimental rabbits fed with cholesterol diet

The aims of this present study were to investigate the potential antioxidant, anti-inflammatory and plaque-reducing activity of Baccaurea angulata (BA) fruit as a new anti-atherogenic plant. Twenty five male rabbits of New Zealand strain used were randomly assigned to five groups. Rabbits were fed e...

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Main Authors:	Mikail, Maryam Abimbola, Adewale, Ahmed Idris, Ibrahim, Muhammad, Hazali, Norazlanshah, Abdull Rasad, Mohammad Syaiful Baharii, Abdul Ghani, Radiah, Abdul Wahab, Ridhwan, Arief Ichwan, Solachuddin Jauhari, Md Isa, Muhammad Lokman, Draman, Samsul, Ishola, Afeez Adekunle, Adros Yahya, Mohammad Noor
Format:	Article
Language:	English
Published:	International Institute of Chemical, Biological & Environmental Engineering (IICBEE) 2013
Subjects:	RM Therapeutics. Pharmacology
Online Access:	http://irep.iium.edu.my/38821/ http://irep.iium.edu.my/38821/ http://irep.iium.edu.my/38821/1/Changes_in_the_Markers_of_Atherosclerosis.pdf

id	iium-38821
recordtype	eprints
spelling	iium-388212014-11-27T08:31:58Z http://irep.iium.edu.my/38821/ Changes in the markers of atherosclerosis following administration of Belimbing dayak (Baccaurea angulata) fruit juice in experimental rabbits fed with cholesterol diet Mikail, Maryam Abimbola Adewale, Ahmed Idris Ibrahim, Muhammad Hazali, Norazlanshah Abdull Rasad, Mohammad Syaiful Baharii Abdul Ghani, Radiah Abdul Wahab, Ridhwan Arief Ichwan, Solachuddin Jauhari Md Isa, Muhammad Lokman Draman, Samsul Ishola, Afeez Adekunle Adros Yahya, Mohammad Noor RM Therapeutics. Pharmacology The aims of this present study were to investigate the potential antioxidant, anti-inflammatory and plaque-reducing activity of Baccaurea angulata (BA) fruit as a new anti-atherogenic plant. Twenty five male rabbits of New Zealand strain used were randomly assigned to five groups. Rabbits were fed either a standard chow diet (group N) or a high-cholesterol diet (groups CH, C1, C2 and C3). Groups C1, C2 and C3 were also given 0.5ml or 1ml or 1.5ml/kg/day BA whole fruit juice respectively. BA juice had high antioxidant activities indicated by the increase in the SOD activity and total antioxidant capacity (TAC), when comparing the C1, C2 and C3 groups with group CH. In the group CH, there was statistically significant increase in IL-8 and IL-18 levels as compared to C1, C2 and C3 groups. Likewise, BA juice reduced plaque formation in rabbits’ aorta. Therefore, BA juice is beneficial in preventing atherosclerosis. International Institute of Chemical, Biological & Environmental Engineering (IICBEE) 2013 Article NonPeerReviewed application/pdf en http://irep.iium.edu.my/38821/1/Changes_in_the_Markers_of_Atherosclerosis.pdf Mikail, Maryam Abimbola and Adewale, Ahmed Idris and Ibrahim, Muhammad and Hazali, Norazlanshah and Abdull Rasad, Mohammad Syaiful Baharii and Abdul Ghani, Radiah and Abdul Wahab, Ridhwan and Arief Ichwan, Solachuddin Jauhari and Md Isa, Muhammad Lokman and Draman, Samsul and Ishola, Afeez Adekunle and Adros Yahya, Mohammad Noor (2013) Changes in the markers of atherosclerosis following administration of Belimbing dayak (Baccaurea angulata) fruit juice in experimental rabbits fed with cholesterol diet. International Journal of Advances in Agricultural & Environmental Engineering (IJAEE), 1 (1). pp. 151-154. ISSN 2349-1523 (O), 2349-1523 (P) http://iicbe.org/siteadmin/upload/4954C614516.pdf
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English
topic	RM Therapeutics. Pharmacology
spellingShingle	RM Therapeutics. Pharmacology Mikail, Maryam Abimbola Adewale, Ahmed Idris Ibrahim, Muhammad Hazali, Norazlanshah Abdull Rasad, Mohammad Syaiful Baharii Abdul Ghani, Radiah Abdul Wahab, Ridhwan Arief Ichwan, Solachuddin Jauhari Md Isa, Muhammad Lokman Draman, Samsul Ishola, Afeez Adekunle Adros Yahya, Mohammad Noor Changes in the markers of atherosclerosis following administration of Belimbing dayak (Baccaurea angulata) fruit juice in experimental rabbits fed with cholesterol diet
description	The aims of this present study were to investigate the potential antioxidant, anti-inflammatory and plaque-reducing activity of Baccaurea angulata (BA) fruit as a new anti-atherogenic plant. Twenty five male rabbits of New Zealand strain used were randomly assigned to five groups. Rabbits were fed either a standard chow diet (group N) or a high-cholesterol diet (groups CH, C1, C2 and C3). Groups C1, C2 and C3 were also given 0.5ml or 1ml or 1.5ml/kg/day BA whole fruit juice respectively. BA juice had high antioxidant activities indicated by the increase in the SOD activity and total antioxidant capacity (TAC), when comparing the C1, C2 and C3 groups with group CH. In the group CH, there was statistically significant increase in IL-8 and IL-18 levels as compared to C1, C2 and C3 groups. Likewise, BA juice reduced plaque formation in rabbits’ aorta. Therefore, BA juice is beneficial in preventing atherosclerosis.
format	Article
author	Mikail, Maryam Abimbola Adewale, Ahmed Idris Ibrahim, Muhammad Hazali, Norazlanshah Abdull Rasad, Mohammad Syaiful Baharii Abdul Ghani, Radiah Abdul Wahab, Ridhwan Arief Ichwan, Solachuddin Jauhari Md Isa, Muhammad Lokman Draman, Samsul Ishola, Afeez Adekunle Adros Yahya, Mohammad Noor
author_facet	Mikail, Maryam Abimbola Adewale, Ahmed Idris Ibrahim, Muhammad Hazali, Norazlanshah Abdull Rasad, Mohammad Syaiful Baharii Abdul Ghani, Radiah Abdul Wahab, Ridhwan Arief Ichwan, Solachuddin Jauhari Md Isa, Muhammad Lokman Draman, Samsul Ishola, Afeez Adekunle Adros Yahya, Mohammad Noor
author_sort	Mikail, Maryam Abimbola
title	Changes in the markers of atherosclerosis following administration of Belimbing dayak (Baccaurea angulata) fruit juice in experimental rabbits fed with cholesterol diet
title_short	Changes in the markers of atherosclerosis following administration of Belimbing dayak (Baccaurea angulata) fruit juice in experimental rabbits fed with cholesterol diet
title_full	Changes in the markers of atherosclerosis following administration of Belimbing dayak (Baccaurea angulata) fruit juice in experimental rabbits fed with cholesterol diet
title_fullStr	Changes in the markers of atherosclerosis following administration of Belimbing dayak (Baccaurea angulata) fruit juice in experimental rabbits fed with cholesterol diet
title_full_unstemmed	Changes in the markers of atherosclerosis following administration of Belimbing dayak (Baccaurea angulata) fruit juice in experimental rabbits fed with cholesterol diet
title_sort	changes in the markers of atherosclerosis following administration of belimbing dayak (baccaurea angulata) fruit juice in experimental rabbits fed with cholesterol diet
publisher	International Institute of Chemical, Biological & Environmental Engineering (IICBEE)
publishDate	2013
url	http://irep.iium.edu.my/38821/ http://irep.iium.edu.my/38821/ http://irep.iium.edu.my/38821/1/Changes_in_the_Markers_of_Atherosclerosis.pdf
first_indexed	2023-09-18T20:55:46Z
last_indexed	2023-09-18T20:55:46Z
_version_	1777410293822914560

Changes in the markers of atherosclerosis following administration of Belimbing dayak (Baccaurea angulata) fruit juice in experimental rabbits fed with cholesterol diet

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