Antimicrobial activity and microbial transformation of ethyl p-methoxycinnamate extracted from Kaempferia Galanga

Ethyl p-methoxycinnamate (EPMC), a major constituent of the Kaempferia galanga rhizome, was transformed to ethyl p-hydroxycinnamate (EPHC) using Aspergillus niger. The EPHC metabolite was elucidated by NMR spectroscopic technique. Antimicrobial microbial study found that EPHC was active against all...

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Main Authors:	Omar, Muhammad Nor, Mohd Hasali, Nor Hazwani, Alfarra, Helmi Yousif, Yarmo, Mohd Ambar, Zuberdi, Ahmad Muzammil
Format:	Article
Language:	English
Published:	Oriental Scientific Publishing Co. 2014
Subjects:	QR Microbiology
Online Access:	http://irep.iium.edu.my/38610/ http://irep.iium.edu.my/38610/ http://irep.iium.edu.my/38610/ http://irep.iium.edu.my/38610/1/EPMC_EPHC_OJCV030I03P1037-1043.pdf

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recordtype	eprints
spelling	iium-386102018-06-19T01:57:42Z http://irep.iium.edu.my/38610/ Antimicrobial activity and microbial transformation of ethyl p-methoxycinnamate extracted from Kaempferia Galanga Omar, Muhammad Nor Mohd Hasali, Nor Hazwani Alfarra, Helmi Yousif Yarmo, Mohd Ambar Zuberdi, Ahmad Muzammil QR Microbiology Ethyl p-methoxycinnamate (EPMC), a major constituent of the Kaempferia galanga rhizome, was transformed to ethyl p-hydroxycinnamate (EPHC) using Aspergillus niger. The EPHC metabolite was elucidated by NMR spectroscopic technique. Antimicrobial microbial study found that EPHC was active against all strains tested with a good minimum inhibitory concentration (MIC). It was active against both Staphylococcus aureus and Bacillus cereus at MIC 333 μg/ml while against Pseudomonas aeruginosa, Escherichia coli and Candida albicans at MIC 111 μg/ml. It was also shown that EPHC exhibited more growth inhibition potential than EPMC. Besides that, EPHC has shown the minimum bactericidal concentration (MBC) toward B. cereus, P. aeruginosa and E. coli at the concentration of 1000 μg/mL while EPMC did not show killing potential toward the tested microorganisms. Oriental Scientific Publishing Co. 2014-09 Article PeerReviewed application/pdf en http://irep.iium.edu.my/38610/1/EPMC_EPHC_OJCV030I03P1037-1043.pdf Omar, Muhammad Nor and Mohd Hasali, Nor Hazwani and Alfarra, Helmi Yousif and Yarmo, Mohd Ambar and Zuberdi, Ahmad Muzammil (2014) Antimicrobial activity and microbial transformation of ethyl p-methoxycinnamate extracted from Kaempferia Galanga. Oriental Journal of Chemistry, 30 (3). pp. 1037-1043. ISSN 0970 - 020X (P), 2231-5039 (O) http://www.orientjchem.org/pdf/vol30no3/OJCV030I03P1037-1043.pdf 10.13005/ojc/300315
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English
topic	QR Microbiology
spellingShingle	QR Microbiology Omar, Muhammad Nor Mohd Hasali, Nor Hazwani Alfarra, Helmi Yousif Yarmo, Mohd Ambar Zuberdi, Ahmad Muzammil Antimicrobial activity and microbial transformation of ethyl p-methoxycinnamate extracted from Kaempferia Galanga
description	Ethyl p-methoxycinnamate (EPMC), a major constituent of the Kaempferia galanga rhizome, was transformed to ethyl p-hydroxycinnamate (EPHC) using Aspergillus niger. The EPHC metabolite was elucidated by NMR spectroscopic technique. Antimicrobial microbial study found that EPHC was active against all strains tested with a good minimum inhibitory concentration (MIC). It was active against both Staphylococcus aureus and Bacillus cereus at MIC 333 μg/ml while against Pseudomonas aeruginosa, Escherichia coli and Candida albicans at MIC 111 μg/ml. It was also shown that EPHC exhibited more growth inhibition potential than EPMC. Besides that, EPHC has shown the minimum bactericidal concentration (MBC) toward B. cereus, P. aeruginosa and E. coli at the concentration of 1000 μg/mL while EPMC did not show killing potential toward the tested microorganisms.
format	Article
author	Omar, Muhammad Nor Mohd Hasali, Nor Hazwani Alfarra, Helmi Yousif Yarmo, Mohd Ambar Zuberdi, Ahmad Muzammil
author_facet	Omar, Muhammad Nor Mohd Hasali, Nor Hazwani Alfarra, Helmi Yousif Yarmo, Mohd Ambar Zuberdi, Ahmad Muzammil
author_sort	Omar, Muhammad Nor
title	Antimicrobial activity and microbial transformation of ethyl p-methoxycinnamate extracted from Kaempferia Galanga
title_short	Antimicrobial activity and microbial transformation of ethyl p-methoxycinnamate extracted from Kaempferia Galanga
title_full	Antimicrobial activity and microbial transformation of ethyl p-methoxycinnamate extracted from Kaempferia Galanga
title_fullStr	Antimicrobial activity and microbial transformation of ethyl p-methoxycinnamate extracted from Kaempferia Galanga
title_full_unstemmed	Antimicrobial activity and microbial transformation of ethyl p-methoxycinnamate extracted from Kaempferia Galanga
title_sort	antimicrobial activity and microbial transformation of ethyl p-methoxycinnamate extracted from kaempferia galanga
publisher	Oriental Scientific Publishing Co.
publishDate	2014
url	http://irep.iium.edu.my/38610/ http://irep.iium.edu.my/38610/ http://irep.iium.edu.my/38610/ http://irep.iium.edu.my/38610/1/EPMC_EPHC_OJCV030I03P1037-1043.pdf
first_indexed	2023-09-18T20:55:28Z
last_indexed	2023-09-18T20:55:28Z
_version_	1777410274427404288

Antimicrobial activity and microbial transformation of ethyl p-methoxycinnamate extracted from Kaempferia Galanga

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