Nanostructured material from hydroxyethyl cellulose for skin tissue engineering

tIn this study, a novel fibrous membrane of hydroxyethyl cellulose (HEC)/poly(vinyl alcohol) blend wassuccessfully fabricated by electrospinning technique and characterized. The concentration of HEC (5%)with PVA (15%) was optimized, blended in different ratios (30–50%) and electrospun to get smoothn...

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Main Authors:	Zulkifli, Farah Hanani, Jahir Hussain, Fathima Shahitha, Abdull Rasad, Mohammad Syaiful Bahari, Mohd Yusoff, Mashitah
Format:	Article
Language:	English English English
Published:	Elsevier Ltd. 2014
Subjects:	Q Science (General)
Online Access:	http://irep.iium.edu.my/38236/ http://irep.iium.edu.my/38236/ http://irep.iium.edu.my/38236/ http://irep.iium.edu.my/38236/1/Nanostructured_materials_from_hydroxyethyl_cellulose_for_skin_tissue_engineering_Carbohdrate_Polymer.pdf http://irep.iium.edu.my/38236/4/38236_Nanostructured%20material%20from%20hydroxyethyl%20cellulose%20for%20skin%20tissue%20engineering_SCOPUS.pdf http://irep.iium.edu.my/38236/5/38236_Nanostructured%20material%20from%20hydroxyethyl%20cellulose%20for%20skin%20tissue%20engineering_WoS.pdf

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recordtype	eprints
spelling	iium-382362017-09-25T13:54:16Z http://irep.iium.edu.my/38236/ Nanostructured material from hydroxyethyl cellulose for skin tissue engineering Zulkifli, Farah Hanani Jahir Hussain, Fathima Shahitha Abdull Rasad, Mohammad Syaiful Bahari Mohd Yusoff, Mashitah Q Science (General) tIn this study, a novel fibrous membrane of hydroxyethyl cellulose (HEC)/poly(vinyl alcohol) blend wassuccessfully fabricated by electrospinning technique and characterized. The concentration of HEC (5%)with PVA (15%) was optimized, blended in different ratios (30–50%) and electrospun to get smoothnanofibers. Nanofibrous membranes were made water insoluble by chemically cross-linking by glu-taraldehyde and used as scaffolds for the skin tissue engineering. The microstructure, morphology,mechanical and thermal properties of the blended HEC/PVA nanofibrous scaffolds were characterized byscanning electron microscope, Fourier transform infrared spectroscopy, differential scanning colorime-try, universal testing machine and thermogravimetric analysis. Cytotoxicity studies on these nanofibrousscaffolds were carried out using human melanoma cells by the MTT assays. The cells were able to attachand spread in the nanofibrous scaffolds as shown by the SEM images. These preliminary results showthat these nanofibrous scaffolds that supports cell adhesion and proliferation is promising for skin tissueengineering. Elsevier Ltd. 2014 Article PeerReviewed application/pdf en http://irep.iium.edu.my/38236/1/Nanostructured_materials_from_hydroxyethyl_cellulose_for_skin_tissue_engineering_Carbohdrate_Polymer.pdf application/pdf en http://irep.iium.edu.my/38236/4/38236_Nanostructured%20material%20from%20hydroxyethyl%20cellulose%20for%20skin%20tissue%20engineering_SCOPUS.pdf application/pdf en http://irep.iium.edu.my/38236/5/38236_Nanostructured%20material%20from%20hydroxyethyl%20cellulose%20for%20skin%20tissue%20engineering_WoS.pdf Zulkifli, Farah Hanani and Jahir Hussain, Fathima Shahitha and Abdull Rasad, Mohammad Syaiful Bahari and Mohd Yusoff, Mashitah (2014) Nanostructured material from hydroxyethyl cellulose for skin tissue engineering. Carbohydrate Polymers, 114. pp. 238-245. E-ISSN 0144-8617 http://www.journals.elsevier.com/carbohydrate-polymers http://dx.doi.org/10.1016/j.carbpol.2014.08.019
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English English English
topic	Q Science (General)
spellingShingle	Q Science (General) Zulkifli, Farah Hanani Jahir Hussain, Fathima Shahitha Abdull Rasad, Mohammad Syaiful Bahari Mohd Yusoff, Mashitah Nanostructured material from hydroxyethyl cellulose for skin tissue engineering
description	tIn this study, a novel fibrous membrane of hydroxyethyl cellulose (HEC)/poly(vinyl alcohol) blend wassuccessfully fabricated by electrospinning technique and characterized. The concentration of HEC (5%)with PVA (15%) was optimized, blended in different ratios (30–50%) and electrospun to get smoothnanofibers. Nanofibrous membranes were made water insoluble by chemically cross-linking by glu-taraldehyde and used as scaffolds for the skin tissue engineering. The microstructure, morphology,mechanical and thermal properties of the blended HEC/PVA nanofibrous scaffolds were characterized byscanning electron microscope, Fourier transform infrared spectroscopy, differential scanning colorime-try, universal testing machine and thermogravimetric analysis. Cytotoxicity studies on these nanofibrousscaffolds were carried out using human melanoma cells by the MTT assays. The cells were able to attachand spread in the nanofibrous scaffolds as shown by the SEM images. These preliminary results showthat these nanofibrous scaffolds that supports cell adhesion and proliferation is promising for skin tissueengineering.
format	Article
author	Zulkifli, Farah Hanani Jahir Hussain, Fathima Shahitha Abdull Rasad, Mohammad Syaiful Bahari Mohd Yusoff, Mashitah
author_facet	Zulkifli, Farah Hanani Jahir Hussain, Fathima Shahitha Abdull Rasad, Mohammad Syaiful Bahari Mohd Yusoff, Mashitah
author_sort	Zulkifli, Farah Hanani
title	Nanostructured material from hydroxyethyl cellulose for skin tissue engineering
title_short	Nanostructured material from hydroxyethyl cellulose for skin tissue engineering
title_full	Nanostructured material from hydroxyethyl cellulose for skin tissue engineering
title_fullStr	Nanostructured material from hydroxyethyl cellulose for skin tissue engineering
title_full_unstemmed	Nanostructured material from hydroxyethyl cellulose for skin tissue engineering
title_sort	nanostructured material from hydroxyethyl cellulose for skin tissue engineering
publisher	Elsevier Ltd.
publishDate	2014
url	http://irep.iium.edu.my/38236/ http://irep.iium.edu.my/38236/ http://irep.iium.edu.my/38236/ http://irep.iium.edu.my/38236/1/Nanostructured_materials_from_hydroxyethyl_cellulose_for_skin_tissue_engineering_Carbohdrate_Polymer.pdf http://irep.iium.edu.my/38236/4/38236_Nanostructured%20material%20from%20hydroxyethyl%20cellulose%20for%20skin%20tissue%20engineering_SCOPUS.pdf http://irep.iium.edu.my/38236/5/38236_Nanostructured%20material%20from%20hydroxyethyl%20cellulose%20for%20skin%20tissue%20engineering_WoS.pdf
first_indexed	2023-09-18T20:54:55Z
last_indexed	2023-09-18T20:54:55Z
_version_	1777410239679692800

Nanostructured material from hydroxyethyl cellulose for skin tissue engineering

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