Mathematics: the bottleneck of cancer research

Cancer is a type of disease typified by uncontrolled cell division. Cancer is a major leading cause of death and responsible for around 13% of all deaths world-wide. There have been various attempts by researchers to understand, diagnose, and cure cancer. There have been numerous advances in terms o...

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Main Authors: Win, Shoon Lei, Htike@Muhammad Yusof, Zaw Zaw, Yusof, Faridah, Noorbatcha, Ibrahim Ali
Format: Conference or Workshop Item
Language:English
Published: 2014
Subjects:
Online Access:http://irep.iium.edu.my/38049/
http://irep.iium.edu.my/38049/
http://irep.iium.edu.my/38049/1/Mathematics_Bottleneck_in_Cancer_Research.pdf
id iium-38049
recordtype eprints
spelling iium-380492018-06-19T04:23:43Z http://irep.iium.edu.my/38049/ Mathematics: the bottleneck of cancer research Win, Shoon Lei Htike@Muhammad Yusof, Zaw Zaw Yusof, Faridah Noorbatcha, Ibrahim Ali T Technology (General) Cancer is a type of disease typified by uncontrolled cell division. Cancer is a major leading cause of death and responsible for around 13% of all deaths world-wide. There have been various attempts by researchers to understand, diagnose, and cure cancer. There have been numerous advances in terms of high-throughput technology such as lab-on-a-chip, electrophoresis, and microarray technology. Because of these advances, there is a persistent need to analyze complex data from these devices. The mathematical analysis technology has been lagging behind the sensing technology. This paper reviews state-of-the-art mathematical techniques utilized in cancer research and posits that mathematics is a bottleneck in all the five areas of cancer research starting from carcinogenesis all the way to therapeutics. Mathematical modeling and analysis play a pivotal role in cancer research. Carcinogenesis can be best understood in terms of mathematics. Despite the fact that cancer is preventable and curable in early stages, the vast majority of patients are diagnosed with cancer very late. Therefore, it is of paramount importance to prevent and detect cancer early. Mathematics always plays a great role in analyzing metabolomic, proteomic, transcriptomic, and genomic data in order to perform diagnosis and prognosis. Moreover, cancer treatment and therapeutics also require mathematical modeling. 2014-06-30 Conference or Workshop Item PeerReviewed application/pdf en http://irep.iium.edu.my/38049/1/Mathematics_Bottleneck_in_Cancer_Research.pdf Win, Shoon Lei and Htike@Muhammad Yusof, Zaw Zaw and Yusof, Faridah and Noorbatcha, Ibrahim Ali (2014) Mathematics: the bottleneck of cancer research. In: International Conference on Mathematical Applications in Engineering (ICMAE’14), 23-25 September 2014, Kuala Lumpur. (In Press) http://www.iium.edu.my/icmae/14/?page_id=505
repository_type Digital Repository
institution_category Local University
institution International Islamic University Malaysia
building IIUM Repository
collection Online Access
language English
topic T Technology (General)
spellingShingle T Technology (General)
Win, Shoon Lei
Htike@Muhammad Yusof, Zaw Zaw
Yusof, Faridah
Noorbatcha, Ibrahim Ali
Mathematics: the bottleneck of cancer research
description Cancer is a type of disease typified by uncontrolled cell division. Cancer is a major leading cause of death and responsible for around 13% of all deaths world-wide. There have been various attempts by researchers to understand, diagnose, and cure cancer. There have been numerous advances in terms of high-throughput technology such as lab-on-a-chip, electrophoresis, and microarray technology. Because of these advances, there is a persistent need to analyze complex data from these devices. The mathematical analysis technology has been lagging behind the sensing technology. This paper reviews state-of-the-art mathematical techniques utilized in cancer research and posits that mathematics is a bottleneck in all the five areas of cancer research starting from carcinogenesis all the way to therapeutics. Mathematical modeling and analysis play a pivotal role in cancer research. Carcinogenesis can be best understood in terms of mathematics. Despite the fact that cancer is preventable and curable in early stages, the vast majority of patients are diagnosed with cancer very late. Therefore, it is of paramount importance to prevent and detect cancer early. Mathematics always plays a great role in analyzing metabolomic, proteomic, transcriptomic, and genomic data in order to perform diagnosis and prognosis. Moreover, cancer treatment and therapeutics also require mathematical modeling.
format Conference or Workshop Item
author Win, Shoon Lei
Htike@Muhammad Yusof, Zaw Zaw
Yusof, Faridah
Noorbatcha, Ibrahim Ali
author_facet Win, Shoon Lei
Htike@Muhammad Yusof, Zaw Zaw
Yusof, Faridah
Noorbatcha, Ibrahim Ali
author_sort Win, Shoon Lei
title Mathematics: the bottleneck of cancer research
title_short Mathematics: the bottleneck of cancer research
title_full Mathematics: the bottleneck of cancer research
title_fullStr Mathematics: the bottleneck of cancer research
title_full_unstemmed Mathematics: the bottleneck of cancer research
title_sort mathematics: the bottleneck of cancer research
publishDate 2014
url http://irep.iium.edu.my/38049/
http://irep.iium.edu.my/38049/
http://irep.iium.edu.my/38049/1/Mathematics_Bottleneck_in_Cancer_Research.pdf
first_indexed 2023-09-18T20:54:36Z
last_indexed 2023-09-18T20:54:36Z
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