Ethanol modified supercritical carbon dioxide extraction of antioxidant rich extract from Pereskia bleo

Supercritical fluid extraction (SFE) of Pereskia bleo leaves was carried out with systematic experimental study to screen and optimize the factors affecting yield and antioxidant activity. Initially, five factors were studied by Plackett–Burman study to screen the most influential factors. Consequen...

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Main Authors:	Sharif, K. M., Rahman, Md. Mokhlesur, Azmir, Jannatul, Shamsudin, Siti Hadijah, Uddin, Md. Sayed, Fahim, T. K., Sarker, Md. Zaidul Islam
Format:	Article
Language:	English
Published:	The Korean Society of Industrial and Engineering Chemistry. 2015
Subjects:	QD Chemistry
Online Access:	http://irep.iium.edu.my/37115/ http://irep.iium.edu.my/37115/ http://irep.iium.edu.my/37115/ http://irep.iium.edu.my/37115/4/SCF_-December-20014.pdf

id	iium-37115
recordtype	eprints
spelling	iium-371152018-05-22T02:14:53Z http://irep.iium.edu.my/37115/ Ethanol modified supercritical carbon dioxide extraction of antioxidant rich extract from Pereskia bleo Sharif, K. M. Rahman, Md. Mokhlesur Azmir, Jannatul Shamsudin, Siti Hadijah Uddin, Md. Sayed Fahim, T. K. Sarker, Md. Zaidul Islam QD Chemistry Supercritical fluid extraction (SFE) of Pereskia bleo leaves was carried out with systematic experimental study to screen and optimize the factors affecting yield and antioxidant activity. Initially, five factors were studied by Plackett–Burman study to screen the most influential factors. Consequently, three significantly affecting factors were optimized by Box–Behnken study. At the optimum condition (52 °C, 36 MPa and 1.5% ethanol of total CO2) yield and IC50 value obtained by SFE were higher than water extract and lower than methanol extract. GC–MS analysis showed that the ethanol modified supercritical carbon dioxide has increased efficiency for extracting antioxidant compounds, α-tocopherol, β-sitosterol and erythritol. The Korean Society of Industrial and Engineering Chemistry. 2015 Article PeerReviewed application/pdf en http://irep.iium.edu.my/37115/4/SCF_-December-20014.pdf Sharif, K. M. and Rahman, Md. Mokhlesur and Azmir, Jannatul and Shamsudin, Siti Hadijah and Uddin, Md. Sayed and Fahim, T. K. and Sarker, Md. Zaidul Islam (2015) Ethanol modified supercritical carbon dioxide extraction of antioxidant rich extract from Pereskia bleo. Journal of Industrial and Engineering Chemistry, 21. pp. 1314-1322. ISSN 1226-086X http://www.sciencedirect.com/science/article/pii/S1226086X14002998 10.1016/j.jiec.2014.05.047
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English
topic	QD Chemistry
spellingShingle	QD Chemistry Sharif, K. M. Rahman, Md. Mokhlesur Azmir, Jannatul Shamsudin, Siti Hadijah Uddin, Md. Sayed Fahim, T. K. Sarker, Md. Zaidul Islam Ethanol modified supercritical carbon dioxide extraction of antioxidant rich extract from Pereskia bleo
description	Supercritical fluid extraction (SFE) of Pereskia bleo leaves was carried out with systematic experimental study to screen and optimize the factors affecting yield and antioxidant activity. Initially, five factors were studied by Plackett–Burman study to screen the most influential factors. Consequently, three significantly affecting factors were optimized by Box–Behnken study. At the optimum condition (52 °C, 36 MPa and 1.5% ethanol of total CO2) yield and IC50 value obtained by SFE were higher than water extract and lower than methanol extract. GC–MS analysis showed that the ethanol modified supercritical carbon dioxide has increased efficiency for extracting antioxidant compounds, α-tocopherol, β-sitosterol and erythritol.
format	Article
author	Sharif, K. M. Rahman, Md. Mokhlesur Azmir, Jannatul Shamsudin, Siti Hadijah Uddin, Md. Sayed Fahim, T. K. Sarker, Md. Zaidul Islam
author_facet	Sharif, K. M. Rahman, Md. Mokhlesur Azmir, Jannatul Shamsudin, Siti Hadijah Uddin, Md. Sayed Fahim, T. K. Sarker, Md. Zaidul Islam
author_sort	Sharif, K. M.
title	Ethanol modified supercritical carbon dioxide extraction of antioxidant rich extract from Pereskia bleo
title_short	Ethanol modified supercritical carbon dioxide extraction of antioxidant rich extract from Pereskia bleo
title_full	Ethanol modified supercritical carbon dioxide extraction of antioxidant rich extract from Pereskia bleo
title_fullStr	Ethanol modified supercritical carbon dioxide extraction of antioxidant rich extract from Pereskia bleo
title_full_unstemmed	Ethanol modified supercritical carbon dioxide extraction of antioxidant rich extract from Pereskia bleo
title_sort	ethanol modified supercritical carbon dioxide extraction of antioxidant rich extract from pereskia bleo
publisher	The Korean Society of Industrial and Engineering Chemistry.
publishDate	2015
url	http://irep.iium.edu.my/37115/ http://irep.iium.edu.my/37115/ http://irep.iium.edu.my/37115/ http://irep.iium.edu.my/37115/4/SCF_-December-20014.pdf
first_indexed	2023-09-18T20:53:13Z
last_indexed	2023-09-18T20:53:13Z
_version_	1777410133363523584

Ethanol modified supercritical carbon dioxide extraction of antioxidant rich extract from Pereskia bleo

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