The impact of Home Medication Review (HMR) in patients with type 2 Diabetes Mellitus (T2DM) living in rural areas in Kuantan, MALAYSIA

OBJECTIVE: To investigate whether Home Medication Review (HMR) conducted by a pharmacist can improve the clinical indices, quality of life and medication adherence in patients with Type 2 Diabetes Mellitus (T2DM). METHOD: Six month prospective, randomized, controlled study. Adult T2DM patients tak...

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Main Authors:	Zin, Che Suraya, Alias, Nor Elina, Ball, Patrick
Format:	Conference or Workshop Item
Language:	English
Published:	2014
Subjects:	RS Pharmacy and materia medica
Online Access:	http://irep.iium.edu.my/36934/ http://irep.iium.edu.my/36934/1/140616_Ispor_montreal_June_2014.pdf

id	iium-36934
recordtype	eprints
spelling	iium-369342018-06-13T04:48:53Z http://irep.iium.edu.my/36934/ The impact of Home Medication Review (HMR) in patients with type 2 Diabetes Mellitus (T2DM) living in rural areas in Kuantan, MALAYSIA Zin, Che Suraya Alias, Nor Elina Ball, Patrick RS Pharmacy and materia medica OBJECTIVE: To investigate whether Home Medication Review (HMR) conducted by a pharmacist can improve the clinical indices, quality of life and medication adherence in patients with Type 2 Diabetes Mellitus (T2DM). METHOD: Six month prospective, randomized, controlled study. Adult T2DM patients taking medications for diabetes for at least two years, with HbA1c>8%, were recruited into the study and randomized to intervention or control. The intervention group received three home visits by a pharmacist (at baseline, 3 months and at 6 months), and one group counselling session with a dietician in addition to the standard medical care. Control group patients only received standard medical care. Primary outcome measures were HbA1c and fasting blood sugar (FBS). Secondary outcome measures include lipid profile (triglycerides, LDL- and HDL-cholesterol); blood pressure (BP); medication adherence (assessed using modified Morisky adherence scale); and quality of life (QoL) assessed using the Short form health survey (SF-36v2). Outcomes were evaluated at baseline, 3 months and at 6 months. RESULT: 73 patients were recruited to the intervention group (38) or the control group (35), with no significant difference identified in baseline parameters. Data was analysed in SPSSv19(IBM) using ANOVA and paired t-test. There were significant improvements from baseline to 6 months in the intervention group in; HbA1c (mean difference (MD) = 1.57, 95% CI[0.88, 2.26], p<0.001); FBS (MD=2.76, 95% CI[0.59,4.94], p=0.009); systolicBP (MD=6.56, 95% CI[0.75,12.36], p=0.022); diastolicBP (MD=4.44, 95% CI[1.11,7.78], p=0.006); triglycerides (MD=0.59, 95% CI[0.24,0.93], p<0.001) and medication adherence (MD=-2.19, 95% CI[-2.73,-1.65], p<0.001). The control group showed no significant changes in outcome measures. QoL improved in the intervention group but declined in controls. CONCLUSION: In this study, HMR conducted by a pharmacist provided significant improvement in health and QoL of patients with Type 2 Diabetes Mellitus. HMR may be beneficial for patients with chronic diseases and for the healthcare system. 2014-06-01 Conference or Workshop Item PeerReviewed application/pdf en http://irep.iium.edu.my/36934/1/140616_Ispor_montreal_June_2014.pdf Zin, Che Suraya and Alias, Nor Elina and Ball, Patrick (2014) The impact of Home Medication Review (HMR) in patients with type 2 Diabetes Mellitus (T2DM) living in rural areas in Kuantan, MALAYSIA. In: ISPOR 19th Annual International Meeting, 31st May to 4th June 2014, Palais Des Congres de Montreal, Canada.
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English
topic	RS Pharmacy and materia medica
spellingShingle	RS Pharmacy and materia medica Zin, Che Suraya Alias, Nor Elina Ball, Patrick The impact of Home Medication Review (HMR) in patients with type 2 Diabetes Mellitus (T2DM) living in rural areas in Kuantan, MALAYSIA
description	OBJECTIVE: To investigate whether Home Medication Review (HMR) conducted by a pharmacist can improve the clinical indices, quality of life and medication adherence in patients with Type 2 Diabetes Mellitus (T2DM). METHOD: Six month prospective, randomized, controlled study. Adult T2DM patients taking medications for diabetes for at least two years, with HbA1c>8%, were recruited into the study and randomized to intervention or control. The intervention group received three home visits by a pharmacist (at baseline, 3 months and at 6 months), and one group counselling session with a dietician in addition to the standard medical care. Control group patients only received standard medical care. Primary outcome measures were HbA1c and fasting blood sugar (FBS). Secondary outcome measures include lipid profile (triglycerides, LDL- and HDL-cholesterol); blood pressure (BP); medication adherence (assessed using modified Morisky adherence scale); and quality of life (QoL) assessed using the Short form health survey (SF-36v2). Outcomes were evaluated at baseline, 3 months and at 6 months. RESULT: 73 patients were recruited to the intervention group (38) or the control group (35), with no significant difference identified in baseline parameters. Data was analysed in SPSSv19(IBM) using ANOVA and paired t-test. There were significant improvements from baseline to 6 months in the intervention group in; HbA1c (mean difference (MD) = 1.57, 95% CI[0.88, 2.26], p<0.001); FBS (MD=2.76, 95% CI[0.59,4.94], p=0.009); systolicBP (MD=6.56, 95% CI[0.75,12.36], p=0.022); diastolicBP (MD=4.44, 95% CI[1.11,7.78], p=0.006); triglycerides (MD=0.59, 95% CI[0.24,0.93], p<0.001) and medication adherence (MD=-2.19, 95% CI[-2.73,-1.65], p<0.001). The control group showed no significant changes in outcome measures. QoL improved in the intervention group but declined in controls. CONCLUSION: In this study, HMR conducted by a pharmacist provided significant improvement in health and QoL of patients with Type 2 Diabetes Mellitus. HMR may be beneficial for patients with chronic diseases and for the healthcare system.
format	Conference or Workshop Item
author	Zin, Che Suraya Alias, Nor Elina Ball, Patrick
author_facet	Zin, Che Suraya Alias, Nor Elina Ball, Patrick
author_sort	Zin, Che Suraya
title	The impact of Home Medication Review (HMR) in patients with type 2 Diabetes Mellitus (T2DM) living in rural areas in Kuantan, MALAYSIA
title_short	The impact of Home Medication Review (HMR) in patients with type 2 Diabetes Mellitus (T2DM) living in rural areas in Kuantan, MALAYSIA
title_full	The impact of Home Medication Review (HMR) in patients with type 2 Diabetes Mellitus (T2DM) living in rural areas in Kuantan, MALAYSIA
title_fullStr	The impact of Home Medication Review (HMR) in patients with type 2 Diabetes Mellitus (T2DM) living in rural areas in Kuantan, MALAYSIA
title_full_unstemmed	The impact of Home Medication Review (HMR) in patients with type 2 Diabetes Mellitus (T2DM) living in rural areas in Kuantan, MALAYSIA
title_sort	impact of home medication review (hmr) in patients with type 2 diabetes mellitus (t2dm) living in rural areas in kuantan, malaysia
publishDate	2014
url	http://irep.iium.edu.my/36934/ http://irep.iium.edu.my/36934/1/140616_Ispor_montreal_June_2014.pdf
first_indexed	2023-09-18T20:52:58Z
last_indexed	2023-09-18T20:52:58Z
_version_	1777410117593989120

The impact of Home Medication Review (HMR) in patients with type 2 Diabetes Mellitus (T2DM) living in rural areas in Kuantan, MALAYSIA

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