Wound healing properties of ethanolic extract of acrostichum aureum and acrostichum speciosum rhizome in rats

This paper presents the assessment of wound healing properties of ethanolic extract of Acrostichum aureum and A. speciosum in rats. It was carried out on 6 treated groups with 6 rats each group. The excisional wound was made on the dorsal interscapular region of each rat by a 6 mm biopsy punch. T1 a...

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Main Authors: Herman, Hendy Putra, Darnis, Deny Susanti, Saad, Shahbudin, Bakhtiar, M. Taher, Ramli, Norazsida
Format: Article
Language:English
Published: Universiti Malaysia Kelantan Publisher 2013
Subjects:
Online Access:http://irep.iium.edu.my/36864/
http://irep.iium.edu.my/36864/
http://irep.iium.edu.my/36864/1/Taher.pdf
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recordtype eprints
spelling iium-368642016-10-20T04:23:18Z http://irep.iium.edu.my/36864/ Wound healing properties of ethanolic extract of acrostichum aureum and acrostichum speciosum rhizome in rats Herman, Hendy Putra Darnis, Deny Susanti Saad, Shahbudin Bakhtiar, M. Taher Ramli, Norazsida RS Pharmacy and materia medica This paper presents the assessment of wound healing properties of ethanolic extract of Acrostichum aureum and A. speciosum in rats. It was carried out on 6 treated groups with 6 rats each group. The excisional wound was made on the dorsal interscapular region of each rat by a 6 mm biopsy punch. T1 and T2 were treated with 5% and 10% A. aureum ethanolic extract in aqua cream, respectively. Meanwhile, T3 and T4 were treated with 5% and 10% A. speciosum ethanolic extract in aqua cream, respectively. Solcoseryl jelly and aqua cream were used as positive and negative controls. The treatments were applied topically twice daily, wound contraction and period of epithelization were measured every 2 days. The results showed that wound treated with 10% A. speciosum (T4) exerted faster wound contraction significantly (p < 0.05) compared to the negative control. It was also enhanced epithelization period (9.33 ± 3.20 days) of the wounds significantly (p < 0.05). In conclusion, these results strongly suggested the beneficial effects of both plant extracts for enhancing wound healing process. Universiti Malaysia Kelantan Publisher 2013 Article PeerReviewed application/pdf en http://irep.iium.edu.my/36864/1/Taher.pdf Herman, Hendy Putra and Darnis, Deny Susanti and Saad, Shahbudin and Bakhtiar, M. Taher and Ramli, Norazsida (2013) Wound healing properties of ethanolic extract of acrostichum aureum and acrostichum speciosum rhizome in rats. Journal of Tropical Resources and Sustainable Science, 1 (2). pp. 42-48. ISSN 2289-3946 http://jtrss.org/JTRSS/volume1/UN-13/
repository_type Digital Repository
institution_category Local University
institution International Islamic University Malaysia
building IIUM Repository
collection Online Access
language English
topic RS Pharmacy and materia medica
spellingShingle RS Pharmacy and materia medica
Herman, Hendy Putra
Darnis, Deny Susanti
Saad, Shahbudin
Bakhtiar, M. Taher
Ramli, Norazsida
Wound healing properties of ethanolic extract of acrostichum aureum and acrostichum speciosum rhizome in rats
description This paper presents the assessment of wound healing properties of ethanolic extract of Acrostichum aureum and A. speciosum in rats. It was carried out on 6 treated groups with 6 rats each group. The excisional wound was made on the dorsal interscapular region of each rat by a 6 mm biopsy punch. T1 and T2 were treated with 5% and 10% A. aureum ethanolic extract in aqua cream, respectively. Meanwhile, T3 and T4 were treated with 5% and 10% A. speciosum ethanolic extract in aqua cream, respectively. Solcoseryl jelly and aqua cream were used as positive and negative controls. The treatments were applied topically twice daily, wound contraction and period of epithelization were measured every 2 days. The results showed that wound treated with 10% A. speciosum (T4) exerted faster wound contraction significantly (p < 0.05) compared to the negative control. It was also enhanced epithelization period (9.33 ± 3.20 days) of the wounds significantly (p < 0.05). In conclusion, these results strongly suggested the beneficial effects of both plant extracts for enhancing wound healing process.
format Article
author Herman, Hendy Putra
Darnis, Deny Susanti
Saad, Shahbudin
Bakhtiar, M. Taher
Ramli, Norazsida
author_facet Herman, Hendy Putra
Darnis, Deny Susanti
Saad, Shahbudin
Bakhtiar, M. Taher
Ramli, Norazsida
author_sort Herman, Hendy Putra
title Wound healing properties of ethanolic extract of acrostichum aureum and acrostichum speciosum rhizome in rats
title_short Wound healing properties of ethanolic extract of acrostichum aureum and acrostichum speciosum rhizome in rats
title_full Wound healing properties of ethanolic extract of acrostichum aureum and acrostichum speciosum rhizome in rats
title_fullStr Wound healing properties of ethanolic extract of acrostichum aureum and acrostichum speciosum rhizome in rats
title_full_unstemmed Wound healing properties of ethanolic extract of acrostichum aureum and acrostichum speciosum rhizome in rats
title_sort wound healing properties of ethanolic extract of acrostichum aureum and acrostichum speciosum rhizome in rats
publisher Universiti Malaysia Kelantan Publisher
publishDate 2013
url http://irep.iium.edu.my/36864/
http://irep.iium.edu.my/36864/
http://irep.iium.edu.my/36864/1/Taher.pdf
first_indexed 2023-09-18T20:52:52Z
last_indexed 2023-09-18T20:52:52Z
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