Chronic khat consumption and its effect on ovarian structure in mice and their offspring

Khat is considered a psychoactive drug and has many side effects on different parts of the body organs. In this study the effects of khat on ovarian structure in parental mice and their offspring were investigated. Twelve male and twelve female mice were given orally a dose of 50mg/kg body weight...

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Main Authors: AlBadri, Cinaria, Al-Ani, Imad Matloub Dally, Hiba, Hassan
Format: Article
Language:English
Published: Department of Anatomy, National University of Singapore 2014
Subjects:
Online Access:http://irep.iium.edu.my/36823/
http://irep.iium.edu.my/36823/
http://irep.iium.edu.my/36823/1/Chronic_Khat_Consumption.pdf
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recordtype eprints
spelling iium-368232018-06-20T01:33:01Z http://irep.iium.edu.my/36823/ Chronic khat consumption and its effect on ovarian structure in mice and their offspring AlBadri, Cinaria Al-Ani, Imad Matloub Dally Hiba, Hassan QL Zoology Khat is considered a psychoactive drug and has many side effects on different parts of the body organs. In this study the effects of khat on ovarian structure in parental mice and their offspring were investigated. Twelve male and twelve female mice were given orally a dose of 50mg/kg body weight of khat extract by gastric gavage for 4 and 8 weeks. After four weeks of treatment, the male and female mice were allowed to mate. Khat treatment continued for the male mice and for the female mice during pregnancy and after giving birth to their offsprings up to 8 weeks. Adult offspring and their parent were killed at the 4th and 8th weeks of treatment. Histological examination of the ovaries showed many corpus luteum and developing Graafi an follicles with mononuclear infi ltration. Department of Anatomy, National University of Singapore 2014-04 Article PeerReviewed application/pdf en http://irep.iium.edu.my/36823/1/Chronic_Khat_Consumption.pdf AlBadri, Cinaria and Al-Ani, Imad Matloub Dally and Hiba, Hassan (2014) Chronic khat consumption and its effect on ovarian structure in mice and their offspring. Annals of Microscopy, 14. pp. 64-69. ISSN 0219-2209 http://www.microscopy.org.sg/journal/vol_14/Annals%20of%20Microscopy%20Vol%2014-Web.pdf
repository_type Digital Repository
institution_category Local University
institution International Islamic University Malaysia
building IIUM Repository
collection Online Access
language English
topic QL Zoology
spellingShingle QL Zoology
AlBadri, Cinaria
Al-Ani, Imad Matloub Dally
Hiba, Hassan
Chronic khat consumption and its effect on ovarian structure in mice and their offspring
description Khat is considered a psychoactive drug and has many side effects on different parts of the body organs. In this study the effects of khat on ovarian structure in parental mice and their offspring were investigated. Twelve male and twelve female mice were given orally a dose of 50mg/kg body weight of khat extract by gastric gavage for 4 and 8 weeks. After four weeks of treatment, the male and female mice were allowed to mate. Khat treatment continued for the male mice and for the female mice during pregnancy and after giving birth to their offsprings up to 8 weeks. Adult offspring and their parent were killed at the 4th and 8th weeks of treatment. Histological examination of the ovaries showed many corpus luteum and developing Graafi an follicles with mononuclear infi ltration.
format Article
author AlBadri, Cinaria
Al-Ani, Imad Matloub Dally
Hiba, Hassan
author_facet AlBadri, Cinaria
Al-Ani, Imad Matloub Dally
Hiba, Hassan
author_sort AlBadri, Cinaria
title Chronic khat consumption and its effect on ovarian structure in mice and their offspring
title_short Chronic khat consumption and its effect on ovarian structure in mice and their offspring
title_full Chronic khat consumption and its effect on ovarian structure in mice and their offspring
title_fullStr Chronic khat consumption and its effect on ovarian structure in mice and their offspring
title_full_unstemmed Chronic khat consumption and its effect on ovarian structure in mice and their offspring
title_sort chronic khat consumption and its effect on ovarian structure in mice and their offspring
publisher Department of Anatomy, National University of Singapore
publishDate 2014
url http://irep.iium.edu.my/36823/
http://irep.iium.edu.my/36823/
http://irep.iium.edu.my/36823/1/Chronic_Khat_Consumption.pdf
first_indexed 2023-09-18T20:52:47Z
last_indexed 2023-09-18T20:52:47Z
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