Synthesis and characterization of functionalized Se-MCM-41 a new drug carrier mesopore composite

Various nanocomposite materials play a number of important roles in modern science and technology including pharmaceutical science. Among these materials, mesoporous materials cover a large number of applications in drug delivery system. Mesoporous Se-MCM‐41 is one of the mesoporous materials used n...

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Main Authors:	Rahman, Md. Mokhlesur, Yusof, Alias Mohd, Yusan, Sabrie, Ansary , Rezaul H.
Format:	Conference or Workshop Item
Language:	English
Published:	2014
Subjects:	R Medicine (General)
Online Access:	http://irep.iium.edu.my/36595/ http://irep.iium.edu.my/36595/ http://irep.iium.edu.my/36595/1/mokhlesur.pdf

id	iium-36595
recordtype	eprints
spelling	iium-365952018-05-23T03:22:36Z http://irep.iium.edu.my/36595/ Synthesis and characterization of functionalized Se-MCM-41 a new drug carrier mesopore composite Rahman, Md. Mokhlesur Yusof, Alias Mohd Yusan, Sabrie Ansary , Rezaul H. R Medicine (General) Various nanocomposite materials play a number of important roles in modern science and technology including pharmaceutical science. Among these materials, mesoporous materials cover a large number of applications in drug delivery system. Mesoporous Se-MCM‐41 is one of the mesoporous materials used nowadays as a drug carrier. The quantitative incorporation and high dispersion of selenium nanoparticles into MCM-41 has been made possible by the coordination between Se (IV) ion and APTES-anchored MCM-41. The samples were characterized by X-ray powder diffraction, Fourier-transformed infrared spectroscopy (FTIR), scanning electron microscopy (SEM), nitrogen adsorption–desorption via multi point Brunauer, Emmett and Teller (BET) analysis, Raman spectroscopy and UV-Vis diffusion reflection spectroscopy (UV-vis/DRS). X-ray diffraction patterns indicated the existence of the synthesized Se nanoparticles as a crystalline structure with the functionalized material retaining the standard MCM-41 structure. Results from FTIR and Raman spectroscopy demonstrated that the Se and amino groups are incorporated into the Si–O framework. Nitrogen adsorption was used to determine specific surface area, pore diameter and pore volume in the MCM-41 and Se-MCM-41 mesoporous molecular sieves. The increase in cell parameter and the decrease in surface area observed by N2 adsorption–desorption technique were taken as evidence of selenium introduction inside the MCM-41 framework. The presence of a strong absorption band centered at ca. 210 nm in the diffused reflectance UV–vis spectra could explain the presence of hexagonal selenium in the silica network. 2014-12-19 Conference or Workshop Item PeerReviewed application/pdf en http://irep.iium.edu.my/36595/1/mokhlesur.pdf Rahman, Md. Mokhlesur and Yusof, Alias Mohd and Yusan, Sabrie and Ansary , Rezaul H. (2014) Synthesis and characterization of functionalized Se-MCM-41 a new drug carrier mesopore composite. In: International Conference on Nanotechnology in Medicine (NanoMED), 26-28 Feb. 2014, Faculty of Pharmacy, UCL, London. http://www.nanomed.uk.com/publications.html
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English
topic	R Medicine (General)
spellingShingle	R Medicine (General) Rahman, Md. Mokhlesur Yusof, Alias Mohd Yusan, Sabrie Ansary , Rezaul H. Synthesis and characterization of functionalized Se-MCM-41 a new drug carrier mesopore composite
description	Various nanocomposite materials play a number of important roles in modern science and technology including pharmaceutical science. Among these materials, mesoporous materials cover a large number of applications in drug delivery system. Mesoporous Se-MCM‐41 is one of the mesoporous materials used nowadays as a drug carrier. The quantitative incorporation and high dispersion of selenium nanoparticles into MCM-41 has been made possible by the coordination between Se (IV) ion and APTES-anchored MCM-41. The samples were characterized by X-ray powder diffraction, Fourier-transformed infrared spectroscopy (FTIR), scanning electron microscopy (SEM), nitrogen adsorption–desorption via multi point Brunauer, Emmett and Teller (BET) analysis, Raman spectroscopy and UV-Vis diffusion reflection spectroscopy (UV-vis/DRS). X-ray diffraction patterns indicated the existence of the synthesized Se nanoparticles as a crystalline structure with the functionalized material retaining the standard MCM-41 structure. Results from FTIR and Raman spectroscopy demonstrated that the Se and amino groups are incorporated into the Si–O framework. Nitrogen adsorption was used to determine specific surface area, pore diameter and pore volume in the MCM-41 and Se-MCM-41 mesoporous molecular sieves. The increase in cell parameter and the decrease in surface area observed by N2 adsorption–desorption technique were taken as evidence of selenium introduction inside the MCM-41 framework. The presence of a strong absorption band centered at ca. 210 nm in the diffused reflectance UV–vis spectra could explain the presence of hexagonal selenium in the silica network.
format	Conference or Workshop Item
author	Rahman, Md. Mokhlesur Yusof, Alias Mohd Yusan, Sabrie Ansary , Rezaul H.
author_facet	Rahman, Md. Mokhlesur Yusof, Alias Mohd Yusan, Sabrie Ansary , Rezaul H.
author_sort	Rahman, Md. Mokhlesur
title	Synthesis and characterization of functionalized Se-MCM-41 a new drug carrier mesopore composite
title_short	Synthesis and characterization of functionalized Se-MCM-41 a new drug carrier mesopore composite
title_full	Synthesis and characterization of functionalized Se-MCM-41 a new drug carrier mesopore composite
title_fullStr	Synthesis and characterization of functionalized Se-MCM-41 a new drug carrier mesopore composite
title_full_unstemmed	Synthesis and characterization of functionalized Se-MCM-41 a new drug carrier mesopore composite
title_sort	synthesis and characterization of functionalized se-mcm-41 a new drug carrier mesopore composite
publishDate	2014
url	http://irep.iium.edu.my/36595/ http://irep.iium.edu.my/36595/ http://irep.iium.edu.my/36595/1/mokhlesur.pdf
first_indexed	2023-09-18T20:52:25Z
last_indexed	2023-09-18T20:52:25Z
_version_	1777410082388049920

Synthesis and characterization of functionalized Se-MCM-41 a new drug carrier mesopore composite

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