Perioperative blood loss evaluation in tumour-related limb salvage pelvic resections

Introduction and Objectives: Pelvic tumour resections are associated with extensive blood loss. Various options of blood management in surgery are available but limited use particularly for such procedures. Identifying predictive factors for extensive blood loss is essential. This study aims to eval...

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Main Authors:	Sharifudin, Mohd Ariff, Wan, Zulmi, Wan Ismail, Wan Faisham Numan, Mat Zin, Nor Azman, Mohamed Amin, Mohamed Azril, Goh, Kian Liang
Format:	Conference or Workshop Item
Language:	English English
Published:	2014
Subjects:	RB Pathology RC0254 Neoplasms. Tumors. Oncology (including Cancer) RD701 Orthopedics
Online Access:	http://irep.iium.edu.my/36354/ http://irep.iium.edu.my/36354/2/APMSTS_2014_-_POSTER_-_PELVIC_BLEEDING.pdf http://irep.iium.edu.my/36354/5/perioperative_blood.pdf

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spelling	iium-363542018-12-20T00:24:42Z http://irep.iium.edu.my/36354/ Perioperative blood loss evaluation in tumour-related limb salvage pelvic resections Sharifudin, Mohd Ariff Wan, Zulmi Wan Ismail, Wan Faisham Numan Mat Zin, Nor Azman Mohamed Amin, Mohamed Azril Goh, Kian Liang RB Pathology RC0254 Neoplasms. Tumors. Oncology (including Cancer) RD701 Orthopedics Introduction and Objectives: Pelvic tumour resections are associated with extensive blood loss. Various options of blood management in surgery are available but limited use particularly for such procedures. Identifying predictive factors for extensive blood loss is essential. This study aims to evaluate the volume of blood loss in limb salvage pelvic resections and identify the risk factors for large amount of perioperative blood loss. Methodology: Twenty-five cases of pelvic tumours of various types, whom underwent resections performed between year 2000 and 2010 in a single tumour referral centre were reviewed. External hemipelvectomies and sacral resections were not included. Total perioperative blood loss consisted of estimated intra-operative blood loss and the drainage volume on the first day post-surgery. Large amount of blood loss was defined as total loss of more than 3000ml. Statistical analysis performed using Fisher’s exact test. Results: Six (24.0%) patients had total blood loss greater than 3000ml. Resections of primary bone sarcomas (osteosarcoma and chondrosarcoma) have the highest mean blood loss volume (6556.67ml and 1768.57ml, respectively). Large amount of blood loss is significantly associated with the involvement of the acetabulum. Other associated factors include tumour recurrence and duration of surgery. Extensive blood loss was not significantly associated with neo-adjuvant therapies and pre-operative embolization. Conclusion: Large amount of blood loss should be anticipated when planning for resections of tumours involving the acetabular region. Radiation therapy prior to surgery was believed to increase the risk of bleeding intra-operatively, was not observed in this study. 2014-04 Conference or Workshop Item PeerReviewed application/pdf en http://irep.iium.edu.my/36354/2/APMSTS_2014_-_POSTER_-_PELVIC_BLEEDING.pdf application/pdf en http://irep.iium.edu.my/36354/5/perioperative_blood.pdf Sharifudin, Mohd Ariff and Wan, Zulmi and Wan Ismail, Wan Faisham Numan and Mat Zin, Nor Azman and Mohamed Amin, Mohamed Azril and Goh, Kian Liang (2014) Perioperative blood loss evaluation in tumour-related limb salvage pelvic resections. In: 10th Annual Asia Pacific Musculoskeletal Tumour Society (APMSTS) Scientific Meeting, 9-11 April 2014, Grand Hyatt Melbourne Australia.
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English English
topic	RB Pathology RC0254 Neoplasms. Tumors. Oncology (including Cancer) RD701 Orthopedics
spellingShingle	RB Pathology RC0254 Neoplasms. Tumors. Oncology (including Cancer) RD701 Orthopedics Sharifudin, Mohd Ariff Wan, Zulmi Wan Ismail, Wan Faisham Numan Mat Zin, Nor Azman Mohamed Amin, Mohamed Azril Goh, Kian Liang Perioperative blood loss evaluation in tumour-related limb salvage pelvic resections
description	Introduction and Objectives: Pelvic tumour resections are associated with extensive blood loss. Various options of blood management in surgery are available but limited use particularly for such procedures. Identifying predictive factors for extensive blood loss is essential. This study aims to evaluate the volume of blood loss in limb salvage pelvic resections and identify the risk factors for large amount of perioperative blood loss. Methodology: Twenty-five cases of pelvic tumours of various types, whom underwent resections performed between year 2000 and 2010 in a single tumour referral centre were reviewed. External hemipelvectomies and sacral resections were not included. Total perioperative blood loss consisted of estimated intra-operative blood loss and the drainage volume on the first day post-surgery. Large amount of blood loss was defined as total loss of more than 3000ml. Statistical analysis performed using Fisher’s exact test. Results: Six (24.0%) patients had total blood loss greater than 3000ml. Resections of primary bone sarcomas (osteosarcoma and chondrosarcoma) have the highest mean blood loss volume (6556.67ml and 1768.57ml, respectively). Large amount of blood loss is significantly associated with the involvement of the acetabulum. Other associated factors include tumour recurrence and duration of surgery. Extensive blood loss was not significantly associated with neo-adjuvant therapies and pre-operative embolization. Conclusion: Large amount of blood loss should be anticipated when planning for resections of tumours involving the acetabular region. Radiation therapy prior to surgery was believed to increase the risk of bleeding intra-operatively, was not observed in this study.
format	Conference or Workshop Item
author	Sharifudin, Mohd Ariff Wan, Zulmi Wan Ismail, Wan Faisham Numan Mat Zin, Nor Azman Mohamed Amin, Mohamed Azril Goh, Kian Liang
author_facet	Sharifudin, Mohd Ariff Wan, Zulmi Wan Ismail, Wan Faisham Numan Mat Zin, Nor Azman Mohamed Amin, Mohamed Azril Goh, Kian Liang
author_sort	Sharifudin, Mohd Ariff
title	Perioperative blood loss evaluation in tumour-related limb salvage pelvic resections
title_short	Perioperative blood loss evaluation in tumour-related limb salvage pelvic resections
title_full	Perioperative blood loss evaluation in tumour-related limb salvage pelvic resections
title_fullStr	Perioperative blood loss evaluation in tumour-related limb salvage pelvic resections
title_full_unstemmed	Perioperative blood loss evaluation in tumour-related limb salvage pelvic resections
title_sort	perioperative blood loss evaluation in tumour-related limb salvage pelvic resections
publishDate	2014
url	http://irep.iium.edu.my/36354/ http://irep.iium.edu.my/36354/2/APMSTS_2014_-_POSTER_-_PELVIC_BLEEDING.pdf http://irep.iium.edu.my/36354/5/perioperative_blood.pdf
first_indexed	2023-09-18T20:52:04Z
last_indexed	2023-09-18T20:52:04Z
_version_	1777410060893290496

Perioperative blood loss evaluation in tumour-related limb salvage pelvic resections

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