Anti bacterial activity of pyranocoumarins and crude extracts of Calophyllum symingtonianum

The genus Calophyllum which belongs to Guttderae family is known as ‘bintangor’ by Malay local folks. Previous phytochemicals studies on several Calophyllum species successfully isolated group of pyranocoumarins. In this study, a phytochemical analysis of C. symingtonianum M. R. Hend & Wyatt-Sm....

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Main Authors:	Aminudin, Nurul Iman, Ahmad, Farediah, Bakhtiar, M. Taher
Format:	Conference or Workshop Item
Language:	English
Published:	2014
Subjects:	RS Pharmacy and materia medica
Online Access:	http://irep.iium.edu.my/36159/ http://irep.iium.edu.my/36159/ http://irep.iium.edu.my/36159/1/Binder1.pdf

id	iium-36159
recordtype	eprints
spelling	iium-361592018-06-20T06:41:43Z http://irep.iium.edu.my/36159/ Anti bacterial activity of pyranocoumarins and crude extracts of Calophyllum symingtonianum Aminudin, Nurul Iman Ahmad, Farediah Bakhtiar, M. Taher RS Pharmacy and materia medica The genus Calophyllum which belongs to Guttderae family is known as ‘bintangor’ by Malay local folks. Previous phytochemicals studies on several Calophyllum species successfully isolated group of pyranocoumarins. In this study, a phytochemical analysis of C. symingtonianum M. R. Hend & Wyatt-Sm. was conducted involving stem barks, leaves and heartwood. Cold extraction method was employed by using dichloromethane and methanol to give the respective crude extracts. Two pyranocoumarins were successfully isolated from stem bark dichloromethane crude extract identified as inophyllum D and isocordato-oblongic acid. Screening on their antibacterial activities were evaluated against B. subtilis, S. aureus, P. aeruginosa, P. putida and E. coli by using disc diffusion (DD), minimum inhibition concentration (MIC) and minimum bactericidal concentration (MBC) methods. The MBC values showed only the methanol stem bark crude extract inhibited P. aeruginosa and E. coli growth each at 225 ug/mI. The methanol heartwood crude extract moderately inhibited the growth of S. aureus, P. aeruginosa and P. putida each at 450 ug/mL. 2014-03 Conference or Workshop Item NonPeerReviewed application/pdf en http://irep.iium.edu.my/36159/1/Binder1.pdf Aminudin, Nurul Iman and Ahmad, Farediah and Bakhtiar, M. Taher (2014) Anti bacterial activity of pyranocoumarins and crude extracts of Calophyllum symingtonianum. In: International Conference on Natural Products 2014, 18th-19th March 2014, Palm Garden Hotel, IOI Resorts, Putrajaya, Malaysia. http://www.ukm.my/icnp2014/
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English
topic	RS Pharmacy and materia medica
spellingShingle	RS Pharmacy and materia medica Aminudin, Nurul Iman Ahmad, Farediah Bakhtiar, M. Taher Anti bacterial activity of pyranocoumarins and crude extracts of Calophyllum symingtonianum
description	The genus Calophyllum which belongs to Guttderae family is known as ‘bintangor’ by Malay local folks. Previous phytochemicals studies on several Calophyllum species successfully isolated group of pyranocoumarins. In this study, a phytochemical analysis of C. symingtonianum M. R. Hend & Wyatt-Sm. was conducted involving stem barks, leaves and heartwood. Cold extraction method was employed by using dichloromethane and methanol to give the respective crude extracts. Two pyranocoumarins were successfully isolated from stem bark dichloromethane crude extract identified as inophyllum D and isocordato-oblongic acid. Screening on their antibacterial activities were evaluated against B. subtilis, S. aureus, P. aeruginosa, P. putida and E. coli by using disc diffusion (DD), minimum inhibition concentration (MIC) and minimum bactericidal concentration (MBC) methods. The MBC values showed only the methanol stem bark crude extract inhibited P. aeruginosa and E. coli growth each at 225 ug/mI. The methanol heartwood crude extract moderately inhibited the growth of S. aureus, P. aeruginosa and P. putida each at 450 ug/mL.
format	Conference or Workshop Item
author	Aminudin, Nurul Iman Ahmad, Farediah Bakhtiar, M. Taher
author_facet	Aminudin, Nurul Iman Ahmad, Farediah Bakhtiar, M. Taher
author_sort	Aminudin, Nurul Iman
title	Anti bacterial activity of pyranocoumarins and crude extracts of Calophyllum symingtonianum
title_short	Anti bacterial activity of pyranocoumarins and crude extracts of Calophyllum symingtonianum
title_full	Anti bacterial activity of pyranocoumarins and crude extracts of Calophyllum symingtonianum
title_fullStr	Anti bacterial activity of pyranocoumarins and crude extracts of Calophyllum symingtonianum
title_full_unstemmed	Anti bacterial activity of pyranocoumarins and crude extracts of Calophyllum symingtonianum
title_sort	anti bacterial activity of pyranocoumarins and crude extracts of calophyllum symingtonianum
publishDate	2014
url	http://irep.iium.edu.my/36159/ http://irep.iium.edu.my/36159/ http://irep.iium.edu.my/36159/1/Binder1.pdf
first_indexed	2023-09-18T20:51:46Z
last_indexed	2023-09-18T20:51:46Z
_version_	1777410041674989568

Anti bacterial activity of pyranocoumarins and crude extracts of Calophyllum symingtonianum

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