Synthesis and characterization of various type of Azines as potential bioactive agents

Five Azines (HMB, ANGDA, HHS, HBrS and EMB) were successfully synthesized and evaluated for their antimicrobial activities against various strains of microbes and cytotoxic activities against human breast adenocarcinoma (MCF-7) and non-small lung carcinoma (H1299) cell lines. All the compounds were...

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Main Authors:	How, Fiona Ni Foong, Abdul Malek, Nurfathiah, Solachuddin Jauhari, Arief Ichwan
Format:	Conference or Workshop Item
Language:	English
Published:	2013
Subjects:	QD Chemistry
Online Access:	http://irep.iium.edu.my/34700/ http://irep.iium.edu.my/34700/ http://irep.iium.edu.my/34700/1/rp011_ICECB2013-C0023.pdf

id	iium-34700
recordtype	eprints
spelling	iium-347002014-02-24T06:16:21Z http://irep.iium.edu.my/34700/ Synthesis and characterization of various type of Azines as potential bioactive agents How, Fiona Ni Foong Abdul Malek, Nurfathiah Solachuddin Jauhari, Arief Ichwan QD Chemistry Five Azines (HMB, ANGDA, HHS, HBrS and EMB) were successfully synthesized and evaluated for their antimicrobial activities against various strains of microbes and cytotoxic activities against human breast adenocarcinoma (MCF-7) and non-small lung carcinoma (H1299) cell lines. All the compounds were characterized with FTIR spectroscopy and further confirmed with single crystal X-Ray diffraction analyses. Screening of antimicrobial activities showed HMB was selectively against K. pneumonia and C. albicans. Cytotoxic activity was evaluated against breast adenocarcinoma, MCF-7 and non-small lung, H1299 cancer cell lines. All of the compounds were active, particularly ANGDA and HMB were tested to be most potent against both MCF-7 and H1299 cell lines. 2013 Conference or Workshop Item PeerReviewed application/pdf en http://irep.iium.edu.my/34700/1/rp011_ICECB2013-C0023.pdf How, Fiona Ni Foong and Abdul Malek, Nurfathiah and Solachuddin Jauhari, Arief Ichwan (2013) Synthesis and characterization of various type of Azines as potential bioactive agents. In: 2013 2nd International Conference on Environment, Chemistry and Biology (IPCBEE), 13th - 14th Dec. 2013, Stockholm, Sweden. http://www.ipcbee.com/vol59/009-ICECB2013-C0023.pdf
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English
topic	QD Chemistry
spellingShingle	QD Chemistry How, Fiona Ni Foong Abdul Malek, Nurfathiah Solachuddin Jauhari, Arief Ichwan Synthesis and characterization of various type of Azines as potential bioactive agents
description	Five Azines (HMB, ANGDA, HHS, HBrS and EMB) were successfully synthesized and evaluated for their antimicrobial activities against various strains of microbes and cytotoxic activities against human breast adenocarcinoma (MCF-7) and non-small lung carcinoma (H1299) cell lines. All the compounds were characterized with FTIR spectroscopy and further confirmed with single crystal X-Ray diffraction analyses. Screening of antimicrobial activities showed HMB was selectively against K. pneumonia and C. albicans. Cytotoxic activity was evaluated against breast adenocarcinoma, MCF-7 and non-small lung, H1299 cancer cell lines. All of the compounds were active, particularly ANGDA and HMB were tested to be most potent against both MCF-7 and H1299 cell lines.
format	Conference or Workshop Item
author	How, Fiona Ni Foong Abdul Malek, Nurfathiah Solachuddin Jauhari, Arief Ichwan
author_facet	How, Fiona Ni Foong Abdul Malek, Nurfathiah Solachuddin Jauhari, Arief Ichwan
author_sort	How, Fiona Ni Foong
title	Synthesis and characterization of various type of Azines as potential bioactive agents
title_short	Synthesis and characterization of various type of Azines as potential bioactive agents
title_full	Synthesis and characterization of various type of Azines as potential bioactive agents
title_fullStr	Synthesis and characterization of various type of Azines as potential bioactive agents
title_full_unstemmed	Synthesis and characterization of various type of Azines as potential bioactive agents
title_sort	synthesis and characterization of various type of azines as potential bioactive agents
publishDate	2013
url	http://irep.iium.edu.my/34700/ http://irep.iium.edu.my/34700/ http://irep.iium.edu.my/34700/1/rp011_ICECB2013-C0023.pdf
first_indexed	2023-09-18T20:49:56Z
last_indexed	2023-09-18T20:49:56Z
_version_	1777409926642008064

Synthesis and characterization of various type of Azines as potential bioactive agents

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