Diabetic induced mice treated with olive leaves (Olea europaea) aqueous extract

Due to the widespread prevalence of diabetes and the severity of complication, extensive research are underway to find more effective remedies to improve the life of those affected by the disease. Diabetes mellitus is chronic disease caused by inhered and/or acquired deficiency in production of insu...

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Main Authors:	AlBadri, Cinaria T., Al-Ani, Imad Matloub Dally
Format:	Conference or Workshop Item
Language:	English
Published:	2011
Subjects:	QM Human anatomy QP Physiology R Medicine (General) RB Pathology RM300 Drugs and their action
Online Access:	http://irep.iium.edu.my/34360/ http://irep.iium.edu.my/34360/1/Produced_by_convert-jpg-to-pdf.net_%284%29.pdf

id	iium-34360
recordtype	eprints
spelling	iium-343602015-12-18T02:45:23Z http://irep.iium.edu.my/34360/ Diabetic induced mice treated with olive leaves (Olea europaea) aqueous extract AlBadri, Cinaria T. Al-Ani, Imad Matloub Dally QM Human anatomy QP Physiology R Medicine (General) RB Pathology RM300 Drugs and their action Due to the widespread prevalence of diabetes and the severity of complication, extensive research are underway to find more effective remedies to improve the life of those affected by the disease. Diabetes mellitus is chronic disease caused by inhered and/or acquired deficiency in production of insulin by the pancreas which results in increase concentration of blood glucose level (1).The objectives of this study were to investigate the effects of the aqueous extract of Olea europaea on serum glucose level and histopathological changes in islets of Langerhans in an induced-diabetic mellitus in mice (2, 3). Animals were anaesthetized by diethyl ether after fasting for up to 13 hours and on day 7, 14, 21 and 28 the blood specimens were collected and the serum separated. Serum glucose levels were determined by the glucose oxidase method. The pancreas was excised, ﬁxed in the Boon’s solution and processed for histological studies. The results showed that administration of the aqueous extract exhibited a signiﬁcant increase in the average size of islets of Langerhans of the streptozotocin diabetic animals, while the treatment with Olea europaea aqueous extract showed a marked reduction in the islet size. 1.Sexton WJ, Jarow JP. J.Urology, 1997; 49: 508-515. 2.Hardman JG, Limbird LE. The Pharmacological basis of Therapeutics. 10th Ed. New York. 2011; P 1399. 3.Weir GC, Clore ET, Zmachinski CJ, Bonner-Weir S. Diabetes. 1981; 30: 590-595. 2011-11-12 Conference or Workshop Item PeerReviewed application/pdf en http://irep.iium.edu.my/34360/1/Produced_by_convert-jpg-to-pdf.net_%284%29.pdf AlBadri, Cinaria T. and Al-Ani, Imad Matloub Dally (2011) Diabetic induced mice treated with olive leaves (Olea europaea) aqueous extract. In: Young Life Scientists Symposium Ireland 2011, 12 November 2011, Dublin. (Unpublished)
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English
topic	QM Human anatomy QP Physiology R Medicine (General) RB Pathology RM300 Drugs and their action
spellingShingle	QM Human anatomy QP Physiology R Medicine (General) RB Pathology RM300 Drugs and their action AlBadri, Cinaria T. Al-Ani, Imad Matloub Dally Diabetic induced mice treated with olive leaves (Olea europaea) aqueous extract
description	Due to the widespread prevalence of diabetes and the severity of complication, extensive research are underway to find more effective remedies to improve the life of those affected by the disease. Diabetes mellitus is chronic disease caused by inhered and/or acquired deficiency in production of insulin by the pancreas which results in increase concentration of blood glucose level (1).The objectives of this study were to investigate the effects of the aqueous extract of Olea europaea on serum glucose level and histopathological changes in islets of Langerhans in an induced-diabetic mellitus in mice (2, 3). Animals were anaesthetized by diethyl ether after fasting for up to 13 hours and on day 7, 14, 21 and 28 the blood specimens were collected and the serum separated. Serum glucose levels were determined by the glucose oxidase method. The pancreas was excised, ﬁxed in the Boon’s solution and processed for histological studies. The results showed that administration of the aqueous extract exhibited a signiﬁcant increase in the average size of islets of Langerhans of the streptozotocin diabetic animals, while the treatment with Olea europaea aqueous extract showed a marked reduction in the islet size. 1.Sexton WJ, Jarow JP. J.Urology, 1997; 49: 508-515. 2.Hardman JG, Limbird LE. The Pharmacological basis of Therapeutics. 10th Ed. New York. 2011; P 1399. 3.Weir GC, Clore ET, Zmachinski CJ, Bonner-Weir S. Diabetes. 1981; 30: 590-595.
format	Conference or Workshop Item
author	AlBadri, Cinaria T. Al-Ani, Imad Matloub Dally
author_facet	AlBadri, Cinaria T. Al-Ani, Imad Matloub Dally
author_sort	AlBadri, Cinaria T.
title	Diabetic induced mice treated with olive leaves (Olea europaea) aqueous extract
title_short	Diabetic induced mice treated with olive leaves (Olea europaea) aqueous extract
title_full	Diabetic induced mice treated with olive leaves (Olea europaea) aqueous extract
title_fullStr	Diabetic induced mice treated with olive leaves (Olea europaea) aqueous extract
title_full_unstemmed	Diabetic induced mice treated with olive leaves (Olea europaea) aqueous extract
title_sort	diabetic induced mice treated with olive leaves (olea europaea) aqueous extract
publishDate	2011
url	http://irep.iium.edu.my/34360/ http://irep.iium.edu.my/34360/1/Produced_by_convert-jpg-to-pdf.net_%284%29.pdf
first_indexed	2023-09-18T20:49:32Z
last_indexed	2023-09-18T20:49:32Z
_version_	1777409901361889280

Diabetic induced mice treated with olive leaves (Olea europaea) aqueous extract

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