QSAR study of platelet-activating factor (PAF) receptor binding antagonist

The aim of this study was to find the structure activity relationship between the platelet-activating factor (PAF) receptor binding antagonist activity and the psychochemical properties of flavonoids 1-11 by using quantum chemical QSAR approach. The semi-empirical method quantum method was used t...

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Main Authors:	Abdullah, Nor Hayati, Ibrahim Ali , Noorbatcha, Ling, Sui Kiong
Format:	Conference or Workshop Item
Language:	English English English
Published:	2013
Subjects:	TP248.13 Biotechnology
Online Access:	http://irep.iium.edu.my/34147/ http://irep.iium.edu.my/34147/9/QSAR_-_ICBioE2013_proceedings_paper_pp-684-690.pdf http://irep.iium.edu.my/34147/2/Brochure.pdf http://irep.iium.edu.my/34147/3/ICBIOE_2013_Cover_Page_till_Table_of_contents.pdf

id	iium-34147
recordtype	eprints
spelling	iium-341472014-01-15T02:45:41Z http://irep.iium.edu.my/34147/ QSAR study of platelet-activating factor (PAF) receptor binding antagonist Abdullah, Nor Hayati Ibrahim Ali , Noorbatcha Ling, Sui Kiong TP248.13 Biotechnology The aim of this study was to find the structure activity relationship between the platelet-activating factor (PAF) receptor binding antagonist activity and the psychochemical properties of flavonoids 1-11 by using quantum chemical QSAR approach. The semi-empirical method quantum method was used to optimize the molecular structures of the flavanoids and various quantum chemical descriptors were calculated from the optimized structures. Heuristic and multi-linear regression methods were used to determine the correlation between the quantum chemical properties and the experimental PAF receptor binding inhibitory activity. The best correlation equation was obtained using three descriptors and multi-linear correlation method with R2= 0.9632 2013-07-02 Conference or Workshop Item PeerReviewed application/pdf en http://irep.iium.edu.my/34147/9/QSAR_-_ICBioE2013_proceedings_paper_pp-684-690.pdf application/pdf en http://irep.iium.edu.my/34147/2/Brochure.pdf application/pdf en http://irep.iium.edu.my/34147/3/ICBIOE_2013_Cover_Page_till_Table_of_contents.pdf Abdullah, Nor Hayati and Ibrahim Ali , Noorbatcha and Ling, Sui Kiong (2013) QSAR study of platelet-activating factor (PAF) receptor binding antagonist. In: International Conference on Biotechnology Engineering (ICBioE 2013), 2 – 4 Jul 2013, Kuala Lumpur, Malaysia.
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English English English
topic	TP248.13 Biotechnology
spellingShingle	TP248.13 Biotechnology Abdullah, Nor Hayati Ibrahim Ali , Noorbatcha Ling, Sui Kiong QSAR study of platelet-activating factor (PAF) receptor binding antagonist
description	The aim of this study was to find the structure activity relationship between the platelet-activating factor (PAF) receptor binding antagonist activity and the psychochemical properties of flavonoids 1-11 by using quantum chemical QSAR approach. The semi-empirical method quantum method was used to optimize the molecular structures of the flavanoids and various quantum chemical descriptors were calculated from the optimized structures. Heuristic and multi-linear regression methods were used to determine the correlation between the quantum chemical properties and the experimental PAF receptor binding inhibitory activity. The best correlation equation was obtained using three descriptors and multi-linear correlation method with R2= 0.9632
format	Conference or Workshop Item
author	Abdullah, Nor Hayati Ibrahim Ali , Noorbatcha Ling, Sui Kiong
author_facet	Abdullah, Nor Hayati Ibrahim Ali , Noorbatcha Ling, Sui Kiong
author_sort	Abdullah, Nor Hayati
title	QSAR study of platelet-activating factor (PAF) receptor binding antagonist
title_short	QSAR study of platelet-activating factor (PAF) receptor binding antagonist
title_full	QSAR study of platelet-activating factor (PAF) receptor binding antagonist
title_fullStr	QSAR study of platelet-activating factor (PAF) receptor binding antagonist
title_full_unstemmed	QSAR study of platelet-activating factor (PAF) receptor binding antagonist
title_sort	qsar study of platelet-activating factor (paf) receptor binding antagonist
publishDate	2013
url	http://irep.iium.edu.my/34147/ http://irep.iium.edu.my/34147/9/QSAR_-_ICBioE2013_proceedings_paper_pp-684-690.pdf http://irep.iium.edu.my/34147/2/Brochure.pdf http://irep.iium.edu.my/34147/3/ICBIOE_2013_Cover_Page_till_Table_of_contents.pdf
first_indexed	2023-09-18T20:49:16Z
last_indexed	2023-09-18T20:49:16Z
_version_	1777409884408512512

QSAR study of platelet-activating factor (PAF) receptor binding antagonist

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