Antimicrobial activity and synergic effect of cinnamomum burmannii’s essential oil & its isolated compound (Cinnamaldehyde)

Cinnamomum burmannii is one of the species in Cinnamomum genus and belongs to the Lauraceae family. It has a common name called Indonesian Cassia. The aims of the present study were to investigate the antimicrobial activity of C. burmannii’s essential oil and its major compound, cinnamaldehyde again...

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Main Authors: Awang, Anis Fadhlina Izyani, Darnis, Deny Susanti, Bakhtiar, M. Taher
Format: Conference or Workshop Item
Language:English
Published: 2013
Subjects:
Online Access:http://irep.iium.edu.my/33935/
http://irep.iium.edu.my/33935/
http://irep.iium.edu.my/33935/13/C1213073-2.pdf
id iium-33935
recordtype eprints
spelling iium-339352014-04-16T02:04:19Z http://irep.iium.edu.my/33935/ Antimicrobial activity and synergic effect of cinnamomum burmannii’s essential oil & its isolated compound (Cinnamaldehyde) Awang, Anis Fadhlina Izyani Darnis, Deny Susanti Bakhtiar, M. Taher RS Pharmacy and materia medica Cinnamomum burmannii is one of the species in Cinnamomum genus and belongs to the Lauraceae family. It has a common name called Indonesian Cassia. The aims of the present study were to investigate the antimicrobial activity of C. burmannii’s essential oil and its major compound, cinnamaldehyde against selected microorganisms. This study also aimed to study the synergic effect of C. burmannii’s essential oil as well as cinnamaldehyde upon combining with the current antibiotics. Steam distillation was used for extraction of the essential oil. The isolation of cinnamaldehyde from the essential oil was conducted using column chromatography and the characterization of the compound was analyzed using spectroscopic techniques. The antimicrobial assay was done using micro-dilution methods against three microorganisms in triplicate. The MIC value of essential oil and cinnamaldehyde was found to be 0.33 mg/mL against E. coli, S. aureus and C. albicans. The FIC index upon combination was in the range of 1 < FIC ≤2 which was evaluated as indifference effect. The present study was able to clarify the crucial role of cinnamaldehyde as a potent antimicrobial compound of the C. burmannii’s essential oil. 2013 Conference or Workshop Item NonPeerReviewed application/pdf en http://irep.iium.edu.my/33935/13/C1213073-2.pdf Awang, Anis Fadhlina Izyani and Darnis, Deny Susanti and Bakhtiar, M. Taher (2013) Antimicrobial activity and synergic effect of cinnamomum burmannii’s essential oil & its isolated compound (Cinnamaldehyde). In: International Conference on Chemical, Agricultural and Medical Sciences (CAMS-2013), 29th-30th Dec. 2013, Grand Seasons Hotel, Kuala Lumpur. http://iicbe.org
repository_type Digital Repository
institution_category Local University
institution International Islamic University Malaysia
building IIUM Repository
collection Online Access
language English
topic RS Pharmacy and materia medica
spellingShingle RS Pharmacy and materia medica
Awang, Anis Fadhlina Izyani
Darnis, Deny Susanti
Bakhtiar, M. Taher
Antimicrobial activity and synergic effect of cinnamomum burmannii’s essential oil & its isolated compound (Cinnamaldehyde)
description Cinnamomum burmannii is one of the species in Cinnamomum genus and belongs to the Lauraceae family. It has a common name called Indonesian Cassia. The aims of the present study were to investigate the antimicrobial activity of C. burmannii’s essential oil and its major compound, cinnamaldehyde against selected microorganisms. This study also aimed to study the synergic effect of C. burmannii’s essential oil as well as cinnamaldehyde upon combining with the current antibiotics. Steam distillation was used for extraction of the essential oil. The isolation of cinnamaldehyde from the essential oil was conducted using column chromatography and the characterization of the compound was analyzed using spectroscopic techniques. The antimicrobial assay was done using micro-dilution methods against three microorganisms in triplicate. The MIC value of essential oil and cinnamaldehyde was found to be 0.33 mg/mL against E. coli, S. aureus and C. albicans. The FIC index upon combination was in the range of 1 < FIC ≤2 which was evaluated as indifference effect. The present study was able to clarify the crucial role of cinnamaldehyde as a potent antimicrobial compound of the C. burmannii’s essential oil.
format Conference or Workshop Item
author Awang, Anis Fadhlina Izyani
Darnis, Deny Susanti
Bakhtiar, M. Taher
author_facet Awang, Anis Fadhlina Izyani
Darnis, Deny Susanti
Bakhtiar, M. Taher
author_sort Awang, Anis Fadhlina Izyani
title Antimicrobial activity and synergic effect of cinnamomum burmannii’s essential oil & its isolated compound (Cinnamaldehyde)
title_short Antimicrobial activity and synergic effect of cinnamomum burmannii’s essential oil & its isolated compound (Cinnamaldehyde)
title_full Antimicrobial activity and synergic effect of cinnamomum burmannii’s essential oil & its isolated compound (Cinnamaldehyde)
title_fullStr Antimicrobial activity and synergic effect of cinnamomum burmannii’s essential oil & its isolated compound (Cinnamaldehyde)
title_full_unstemmed Antimicrobial activity and synergic effect of cinnamomum burmannii’s essential oil & its isolated compound (Cinnamaldehyde)
title_sort antimicrobial activity and synergic effect of cinnamomum burmannii’s essential oil & its isolated compound (cinnamaldehyde)
publishDate 2013
url http://irep.iium.edu.my/33935/
http://irep.iium.edu.my/33935/
http://irep.iium.edu.my/33935/13/C1213073-2.pdf
first_indexed 2023-09-18T20:48:59Z
last_indexed 2023-09-18T20:48:59Z
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