The effect of khat on sperm count and motility in parental mice and their offspring
Khat is considered a psychoactive drug and has many side effects on different parts of the body organs. In this study the effects of khat on sperm count and motility in parent mice and their offspring were investigated. Animals were divided into two groups, Group 1 (khat group)contained twelve male...
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2011
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iium-338642015-12-18T02:47:22Z http://irep.iium.edu.my/33864/ The effect of khat on sperm count and motility in parental mice and their offspring AlBadri, Cinaria T. Al-Ani, Imad Matloub Dally Hiba , Hassan M. QM Human anatomy QP Physiology RB Pathology RM300 Drugs and their action Khat is considered a psychoactive drug and has many side effects on different parts of the body organs. In this study the effects of khat on sperm count and motility in parent mice and their offspring were investigated. Animals were divided into two groups, Group 1 (khat group)contained twelve male and twelve female mice, and they were given a daily dose of (50mg/kg) body weight khat extract by gastric gavage for four and eight weeks.Group 2 (control group)also contained twelve male and twelve female mice and received normal access of food and water. After four weeks of treatment, the males and females were allowed to mate and khat treatment continued for up to another four weeks. Twenty four male offspring from group 1 and group 2 were selected randomly and allowed to become mature. Male parent mice were killed at the 4th and 8th weeks of treatment, and their male offspring were killed when they reached maturity age (6-8weeks). Physiologicalexamination of the sperm solution showed that there was a significant increase in sperm count and motility after 4 and 8 weeks of khat treatment, and in their adult offspring.Furthermore, histological changes were found in testicular sections of the adult male mice. Keywords: Khat, offspring, sperm, testes 2011 Conference or Workshop Item PeerReviewed application/pdf en http://irep.iium.edu.my/33864/1/Cinaria_1.jpg application/pdf en http://irep.iium.edu.my/33864/2/copy_cinaria_poster.jpg application/pdf en http://irep.iium.edu.my/33864/3/cover.jpg AlBadri, Cinaria T. and Al-Ani, Imad Matloub Dally and Hiba , Hassan M. (2011) The effect of khat on sperm count and motility in parental mice and their offspring. In: Young Life Scientists Symposium Ireland 2011, 12th November 2011, University College Dublin. |
| repository_type |
Digital Repository |
| institution_category |
Local University |
| institution |
International Islamic University Malaysia |
| building |
IIUM Repository |
| collection |
Online Access |
| language |
English English English |
| topic |
QM Human anatomy QP Physiology RB Pathology RM300 Drugs and their action |
| spellingShingle |
QM Human anatomy QP Physiology RB Pathology RM300 Drugs and their action AlBadri, Cinaria T. Al-Ani, Imad Matloub Dally Hiba , Hassan M. The effect of khat on sperm count and motility in parental mice and their offspring |
| description |
Khat is considered a psychoactive drug and has many side effects on different parts of the body organs. In this study the effects of khat on sperm count and motility in parent mice and their offspring were investigated. Animals were divided into two groups, Group 1 (khat group)contained twelve male and twelve female mice, and they were given a daily dose of (50mg/kg) body weight khat extract by gastric gavage for four and eight weeks.Group 2 (control group)also contained twelve male and twelve female mice and received
normal access of food and water. After four weeks of treatment, the males and females were allowed to mate and khat treatment continued for up to another four weeks. Twenty four male offspring from group 1 and group 2 were selected randomly and allowed to become mature. Male parent mice were killed at the 4th and 8th weeks of treatment, and
their male offspring were killed when they reached maturity age (6-8weeks). Physiologicalexamination of the sperm solution showed that there was a significant increase in sperm count and motility after 4 and 8 weeks of khat treatment, and in their adult offspring.Furthermore, histological changes were found in testicular sections of the adult male mice.
Keywords: Khat, offspring, sperm, testes |
| format |
Conference or Workshop Item |
| author |
AlBadri, Cinaria T. Al-Ani, Imad Matloub Dally Hiba , Hassan M. |
| author_facet |
AlBadri, Cinaria T. Al-Ani, Imad Matloub Dally Hiba , Hassan M. |
| author_sort |
AlBadri, Cinaria T. |
| title |
The effect of khat on sperm count and motility in parental mice and their offspring |
| title_short |
The effect of khat on sperm count and motility in parental mice and their offspring |
| title_full |
The effect of khat on sperm count and motility in parental mice and their offspring |
| title_fullStr |
The effect of khat on sperm count and motility in parental mice and their offspring |
| title_full_unstemmed |
The effect of khat on sperm count and motility in parental mice and their offspring |
| title_sort |
effect of khat on sperm count and motility in parental mice and their offspring |
| publishDate |
2011 |
| url |
http://irep.iium.edu.my/33864/ http://irep.iium.edu.my/33864/1/Cinaria_1.jpg http://irep.iium.edu.my/33864/2/copy_cinaria_poster.jpg http://irep.iium.edu.my/33864/3/cover.jpg |
| first_indexed |
2023-09-18T20:48:57Z |
| last_indexed |
2023-09-18T20:48:57Z |
| _version_ |
1777409864836841472 |