Anti-inflammatory activities of Cinnomomum burmanni Bl
Anti-inflammatory assay was conducted on 20 kinds of traditional Indonesian medicinal herbs using soybean lipxygenase (SLO) and hyaluronidase (HAse). C. burmanni Bl showed highest anti-inflammatory activity. Ethyl acetate fraction from methanol extract of C. burmanni Bl bark showing highest SLO inhi...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
The Korean Society of Food Science and Technology
2005
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| Subjects: | |
| Online Access: | http://irep.iium.edu.my/33756/ http://irep.iium.edu.my/33756/ http://irep.iium.edu.my/33756/1/Khatib_et_al%2C_2005.pdf |
| Summary: | Anti-inflammatory assay was conducted on 20 kinds of traditional Indonesian medicinal herbs using soybean lipxygenase (SLO) and hyaluronidase (HAse). C. burmanni Bl showed highest anti-inflammatory activity. Ethyl acetate fraction from methanol extract of C. burmanni Bl bark showing highest SLO inhibitory activity was isolated using silica gel-60 column chromatography. Two compounds were isolated and purified through preparative HPLC. Through analysis of UV, 1H-NMR, 13-C NMR, EI-MS and FAB+-MS, compounds 1 and 2 were identified as coumarin and 2-hydroxy cinnamaldehyde, respectively, among which 2-hydroxy cinnamaldehyde showed SLO inhibitory activity of IC50=60mikroM. Both compounds did not exhibit HAse inhibitory activity. |
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