Arterial stiffness and its association with dyslipidemia

Arterial stiffness and its association with dyslipidemia

Background: Cardiovascular diseases (CVD) are the leading cause of mortality in Malaysia as well as in other countries. It is associated with, inter alia, many risk factors, such as increasing age, hypertension, diabetes, dyslipidemia, oxidative stress and autonomic dysfunction and arterial stiffnes...

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Main Authors: Mohd Rus, Razman, Ab Rahman, Jamalludin, Muhammed Nordin, Ellyda, Akter, Seikh Farid Uddin
Format: Article
Language:English
Published: Faculty of Medicine, International Islamic University Malaysia 2013
Subjects:
RA0421 Public health. Hygiene. Preventive Medicine
Online Access:http://irep.iium.edu.my/33672/
http://irep.iium.edu.my/33672/
http://irep.iium.edu.my/33672/1/2013_-_Arterial_stiffness_%26_dyslipidemia_e-IMJ_Vol12No2_Page_59-66.pdf
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recordtype eprints
spelling iium-336722019-05-24T03:22:14Z http://irep.iium.edu.my/33672/ Arterial stiffness and its association with dyslipidemia Mohd Rus, Razman Ab Rahman, Jamalludin Muhammed Nordin, Ellyda Akter, Seikh Farid Uddin RA0421 Public health. Hygiene. Preventive Medicine Background: Cardiovascular diseases (CVD) are the leading cause of mortality in Malaysia as well as in other countries. It is associated with, inter alia, many risk factors, such as increasing age, hypertension, diabetes, dyslipidemia, oxidative stress and autonomic dysfunction and arterial stiffness. Objective: The focussed objectives of this study were to measure the prevalence of arterial stiffness and to assess its association with dyslipidemia. Methodology: A cross sectional study was conducted in a rural community in Malaysia. Data were collected using an interviewer administered questionnaire which included three sections – sociodemographic characteristics, personal profile, and past medical history. In addition, Seca Body Meter (Seca 220) was used to measure height and weight. Sphygmomanometer (OMRON Automatic Blood Pressure Monitor HEM 907) and SphygmoCor-AtCor MM3 SERIAL/RS-232 were used for blood pressure and augmentation index (AIx) measurement. Data were analysed using the SPSS for Windows, Version 18.0. Results: The mean age of respondents was 49.5 years, SD±15.6. The prevalence of arterial stiffness was 23.3% (95% Confidence Interval (CI): 16.44 – 30.16). The prevalence of dyslipidemia was 82.9% (95% CI: 76.79 – 89.01). Multivariate logistic regression revealed that total cholesterol was significantly associated with arterial stiffness (OR=4.56, CI 1.10-18.90). Conclusion: The prevalence of dyslipidemia was high. Despite an insignificant association between dyslipidemia and AIx, there is a significant association between TC level and Aix. Faculty of Medicine, International Islamic University Malaysia 2013-12 Article PeerReviewed application/pdf en http://irep.iium.edu.my/33672/1/2013_-_Arterial_stiffness_%26_dyslipidemia_e-IMJ_Vol12No2_Page_59-66.pdf Mohd Rus, Razman and Ab Rahman, Jamalludin and Muhammed Nordin, Ellyda and Akter, Seikh Farid Uddin (2013) Arterial stiffness and its association with dyslipidemia. International Medical Journal Malaysia, 12 (2). pp. 59-65. ISSN 1823-4631 Background: Cardiovascular diseases (CVD) are the leading cause of mortality in Malaysia as well as in other countries. It is associated with, inter alia, many risk factors, such as increasing age, hypertension, diabetes, dyslipidemia, oxidative stress an
repository_type Digital Repository
institution_category Local University
institution International Islamic University Malaysia
building IIUM Repository
collection Online Access
language English
topic RA0421 Public health. Hygiene. Preventive Medicine
spellingShingle RA0421 Public health. Hygiene. Preventive Medicine
Mohd Rus, Razman
Ab Rahman, Jamalludin
Muhammed Nordin, Ellyda
Akter, Seikh Farid Uddin
Arterial stiffness and its association with dyslipidemia
description Background: Cardiovascular diseases (CVD) are the leading cause of mortality in Malaysia as well as in other countries. It is associated with, inter alia, many risk factors, such as increasing age, hypertension, diabetes, dyslipidemia, oxidative stress and autonomic dysfunction and arterial stiffness. Objective: The focussed objectives of this study were to measure the prevalence of arterial stiffness and to assess its association with dyslipidemia. Methodology: A cross sectional study was conducted in a rural community in Malaysia. Data were collected using an interviewer administered questionnaire which included three sections – sociodemographic characteristics, personal profile, and past medical history. In addition, Seca Body Meter (Seca 220) was used to measure height and weight. Sphygmomanometer (OMRON Automatic Blood Pressure Monitor HEM 907) and SphygmoCor-AtCor MM3 SERIAL/RS-232 were used for blood pressure and augmentation index (AIx) measurement. Data were analysed using the SPSS for Windows, Version 18.0. Results: The mean age of respondents was 49.5 years, SD±15.6. The prevalence of arterial stiffness was 23.3% (95% Confidence Interval (CI): 16.44 – 30.16). The prevalence of dyslipidemia was 82.9% (95% CI: 76.79 – 89.01). Multivariate logistic regression revealed that total cholesterol was significantly associated with arterial stiffness (OR=4.56, CI 1.10-18.90). Conclusion: The prevalence of dyslipidemia was high. Despite an insignificant association between dyslipidemia and AIx, there is a significant association between TC level and Aix.
format Article
author Mohd Rus, Razman
Ab Rahman, Jamalludin
Muhammed Nordin, Ellyda
Akter, Seikh Farid Uddin
author_facet Mohd Rus, Razman
Ab Rahman, Jamalludin
Muhammed Nordin, Ellyda
Akter, Seikh Farid Uddin
author_sort Mohd Rus, Razman
title Arterial stiffness and its association with dyslipidemia
title_short Arterial stiffness and its association with dyslipidemia
title_full Arterial stiffness and its association with dyslipidemia
title_fullStr Arterial stiffness and its association with dyslipidemia
title_full_unstemmed Arterial stiffness and its association with dyslipidemia
title_sort arterial stiffness and its association with dyslipidemia
publisher Faculty of Medicine, International Islamic University Malaysia
publishDate 2013
url http://irep.iium.edu.my/33672/
http://irep.iium.edu.my/33672/
http://irep.iium.edu.my/33672/1/2013_-_Arterial_stiffness_%26_dyslipidemia_e-IMJ_Vol12No2_Page_59-66.pdf
first_indexed 2023-09-18T20:48:41Z
last_indexed 2023-09-18T20:48:41Z
_version_ 1777409847671652352

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