Studies on the action of Tamarind (Tamarindus indica) seed extract against some biological properties of King Copra (Ohiophagus Hannah) venom

Annually it has been reported that there are 1.25 million deaths due to snake bite. With the aims of finding herbal remedies that could work synergistically with ant-snack venom, many studies were conducted. It has been shown that ethanolic extract of Tamarind (Tamarindus indica) seed (TSE) has inhi...

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Main Authors:	Maung, Khin Maung, Oothumann , Paakeer, Al-Ani, Imad Matloub Dally
Format:	Conference or Workshop Item
Language:	English
Published:	2013
Subjects:	QM Human anatomy QP Physiology RB Pathology RM300 Drugs and their action
Online Access:	http://irep.iium.edu.my/33645/ http://irep.iium.edu.my/33645/9/Studies_on_the_action_of_Tamarind_%28Tamarindus_indica%29_seed_extract_against_some_biological_properties_of_King_Copra_%28Ohiophagus_Hannah%29_venom.pdf

id	iium-33645
recordtype	eprints
spelling	iium-336452014-01-06T04:15:23Z http://irep.iium.edu.my/33645/ Studies on the action of Tamarind (Tamarindus indica) seed extract against some biological properties of King Copra (Ohiophagus Hannah) venom Maung, Khin Maung Oothumann , Paakeer Al-Ani, Imad Matloub Dally QM Human anatomy QP Physiology RB Pathology RM300 Drugs and their action Annually it has been reported that there are 1.25 million deaths due to snake bite. With the aims of finding herbal remedies that could work synergistically with ant-snack venom, many studies were conducted. It has been shown that ethanolic extract of Tamarind (Tamarindus indica) seed (TSE) has inhibitory effects against lethal action of Vipera russelli and Doboia russelli siamensis. Thus the action of TSE on some biological properties of King Copra (Ohiophagus Hannah) venom (KCV) was studied. KCV was injected subcutaneously into skin of mice and after30 minutes and one hour. TSE was injected subcutaneously near the same site where the venom was injected. None of the mice died, however 4 out of 5 mice of the control group die. To test the effects of myonecrotic action, KCV was injected into the thigh muscles and after one hour, TSE was injected near the same site. Out of 4 mice of each group, 2 mice die before 24 hour. After 24 hour of venom injection, serum creatinine kinase enzyme activity of the surviving mice was measured. The enzyme activity of the TSE treated group was lower than that of the venom control group, but was not statistically significant. Histological study of the muscle was also conducted and found that TSE treated group showed less muscle necrosis than the control group. Thus TSE can neutralize some biological properties of the KCF. 2013 Conference or Workshop Item PeerReviewed application/pdf en http://irep.iium.edu.my/33645/9/Studies_on_the_action_of_Tamarind_%28Tamarindus_indica%29_seed_extract_against_some_biological_properties_of_King_Copra_%28Ohiophagus_Hannah%29_venom.pdf Maung, Khin Maung and Oothumann , Paakeer and Al-Ani, Imad Matloub Dally (2013) Studies on the action of Tamarind (Tamarindus indica) seed extract against some biological properties of King Copra (Ohiophagus Hannah) venom. In: 27th Scientific Meeting of Malaysian Society of Pharmacology and Physiology (MSPP2013), 6-8 September 2013, MS Garden Kuantan. (Unpublished)
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English
topic	QM Human anatomy QP Physiology RB Pathology RM300 Drugs and their action
spellingShingle	QM Human anatomy QP Physiology RB Pathology RM300 Drugs and their action Maung, Khin Maung Oothumann , Paakeer Al-Ani, Imad Matloub Dally Studies on the action of Tamarind (Tamarindus indica) seed extract against some biological properties of King Copra (Ohiophagus Hannah) venom
description	Annually it has been reported that there are 1.25 million deaths due to snake bite. With the aims of finding herbal remedies that could work synergistically with ant-snack venom, many studies were conducted. It has been shown that ethanolic extract of Tamarind (Tamarindus indica) seed (TSE) has inhibitory effects against lethal action of Vipera russelli and Doboia russelli siamensis. Thus the action of TSE on some biological properties of King Copra (Ohiophagus Hannah) venom (KCV) was studied. KCV was injected subcutaneously into skin of mice and after30 minutes and one hour. TSE was injected subcutaneously near the same site where the venom was injected. None of the mice died, however 4 out of 5 mice of the control group die. To test the effects of myonecrotic action, KCV was injected into the thigh muscles and after one hour, TSE was injected near the same site. Out of 4 mice of each group, 2 mice die before 24 hour. After 24 hour of venom injection, serum creatinine kinase enzyme activity of the surviving mice was measured. The enzyme activity of the TSE treated group was lower than that of the venom control group, but was not statistically significant. Histological study of the muscle was also conducted and found that TSE treated group showed less muscle necrosis than the control group. Thus TSE can neutralize some biological properties of the KCF.
format	Conference or Workshop Item
author	Maung, Khin Maung Oothumann , Paakeer Al-Ani, Imad Matloub Dally
author_facet	Maung, Khin Maung Oothumann , Paakeer Al-Ani, Imad Matloub Dally
author_sort	Maung, Khin Maung
title	Studies on the action of Tamarind (Tamarindus indica) seed extract against some biological properties of King Copra (Ohiophagus Hannah) venom
title_short	Studies on the action of Tamarind (Tamarindus indica) seed extract against some biological properties of King Copra (Ohiophagus Hannah) venom
title_full	Studies on the action of Tamarind (Tamarindus indica) seed extract against some biological properties of King Copra (Ohiophagus Hannah) venom
title_fullStr	Studies on the action of Tamarind (Tamarindus indica) seed extract against some biological properties of King Copra (Ohiophagus Hannah) venom
title_full_unstemmed	Studies on the action of Tamarind (Tamarindus indica) seed extract against some biological properties of King Copra (Ohiophagus Hannah) venom
title_sort	studies on the action of tamarind (tamarindus indica) seed extract against some biological properties of king copra (ohiophagus hannah) venom
publishDate	2013
url	http://irep.iium.edu.my/33645/ http://irep.iium.edu.my/33645/9/Studies_on_the_action_of_Tamarind_%28Tamarindus_indica%29_seed_extract_against_some_biological_properties_of_King_Copra_%28Ohiophagus_Hannah%29_venom.pdf
first_indexed	2023-09-18T20:48:38Z
last_indexed	2023-09-18T20:48:38Z
_version_	1777409844761853952

Studies on the action of Tamarind (Tamarindus indica) seed extract against some biological properties of King Copra (Ohiophagus Hannah) venom

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