A review on the formulation and analysis of anti-diabetic agent: Gliclazide
Gliclazide is a second generation sulfonylurea, which is used as antidiabetics drug. It is orally administrated and used for the treatment of non-insulin-dependent diabetes mellitus (NIDDM) and has duration of action of 12 h or more. Beside its hypoglycaemic effects, gliclazide was reported to ha...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Trans Tech Publications, Switzerland
2013
|
| Subjects: | |
| Online Access: | http://irep.iium.edu.my/32319/ http://irep.iium.edu.my/32319/ http://irep.iium.edu.my/32319/ http://irep.iium.edu.my/32319/1/Glaclizide-paper.pdf |
| Summary: | Gliclazide is a second generation sulfonylurea, which is used as antidiabetics drug. It is
orally administrated and used for the treatment of non-insulin-dependent diabetes mellitus (NIDDM)
and has duration of action of 12 h or more. Beside its hypoglycaemic effects, gliclazide was reported
to have many other important effects, such as: suppression of platelet functions, antithrombotic
actions, decreased the production of tumour necrosis factor (TNF) รก by endothelial cells and other
effects. The unique activities of gliclazide has open a new avenue for the drug development research.
This work is aimed to provide comprehensive information about gliclazide and its current research
activities. |
|---|