Assessment of cytotoxicity and toxicity for phosphonium-based deep eutectic solvents

In this work, the cytotoxicity and toxicity of phosphonium-based deep eutectic solvents (DESs) with three hydrogen bond donors, namely glycerine, ethylene glycol, and triethylene glycol were investigated. The cytotoxicity effect was tested using brine shrimp (Artemia salina). The toxicity was inve...

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Main Authors: Hayyan, Maan, Hashim, Mohd. Ali, Al-Saadi, Mohammed A., Hayyan, Adeeb, Alnashef, Inas Muen, Mirghani, Mohamed Elwathig Saeed
Format: Article
Language:English
Published: Elsevier Inc. 2013
Subjects:
Online Access:http://irep.iium.edu.my/32301/
http://irep.iium.edu.my/32301/
http://irep.iium.edu.my/32301/
http://irep.iium.edu.my/32301/1/Assessment_of_cytotoxicity.pdf
id iium-32301
recordtype eprints
spelling iium-323012015-03-16T02:29:43Z http://irep.iium.edu.my/32301/ Assessment of cytotoxicity and toxicity for phosphonium-based deep eutectic solvents Hayyan, Maan Hashim, Mohd. Ali Al-Saadi, Mohammed A. Hayyan, Adeeb Alnashef, Inas Muen Mirghani, Mohamed Elwathig Saeed T Technology (General) In this work, the cytotoxicity and toxicity of phosphonium-based deep eutectic solvents (DESs) with three hydrogen bond donors, namely glycerine, ethylene glycol, and triethylene glycol were investigated. The cytotoxicity effect was tested using brine shrimp (Artemia salina). The toxicity was investigated using the two Gram positive bacteria Bacillus subtilis and Staphylococcus aureus, and two Gram negative bacteria Escherichia coli and Pseudomonas aeruginosa. The cytotoxicity of tested DESs was much higher than that of their individual components, indicating their toxicological behavior was different. It was also found that there was toxic effect on the studied bacteria, indicating their potential application as anti-bacterial agents. To the best of our knowledge, this is the first time the cytotoxicity and toxicity of phosphoniumbased DESs were studied. Elsevier Inc. 2013-09-02 Article PeerReviewed application/pdf en http://irep.iium.edu.my/32301/1/Assessment_of_cytotoxicity.pdf Hayyan, Maan and Hashim, Mohd. Ali and Al-Saadi, Mohammed A. and Hayyan, Adeeb and Alnashef, Inas Muen and Mirghani, Mohamed Elwathig Saeed (2013) Assessment of cytotoxicity and toxicity for phosphonium-based deep eutectic solvents. Chemosphere, 93 (2). pp. 455-459. ISSN 0045-6535 http://www.sciencedirect.com/science/article/pii/S0045653513007480# 10.1016/j.chemosphere.2013.05.013
repository_type Digital Repository
institution_category Local University
institution International Islamic University Malaysia
building IIUM Repository
collection Online Access
language English
topic T Technology (General)
spellingShingle T Technology (General)
Hayyan, Maan
Hashim, Mohd. Ali
Al-Saadi, Mohammed A.
Hayyan, Adeeb
Alnashef, Inas Muen
Mirghani, Mohamed Elwathig Saeed
Assessment of cytotoxicity and toxicity for phosphonium-based deep eutectic solvents
description In this work, the cytotoxicity and toxicity of phosphonium-based deep eutectic solvents (DESs) with three hydrogen bond donors, namely glycerine, ethylene glycol, and triethylene glycol were investigated. The cytotoxicity effect was tested using brine shrimp (Artemia salina). The toxicity was investigated using the two Gram positive bacteria Bacillus subtilis and Staphylococcus aureus, and two Gram negative bacteria Escherichia coli and Pseudomonas aeruginosa. The cytotoxicity of tested DESs was much higher than that of their individual components, indicating their toxicological behavior was different. It was also found that there was toxic effect on the studied bacteria, indicating their potential application as anti-bacterial agents. To the best of our knowledge, this is the first time the cytotoxicity and toxicity of phosphoniumbased DESs were studied.
format Article
author Hayyan, Maan
Hashim, Mohd. Ali
Al-Saadi, Mohammed A.
Hayyan, Adeeb
Alnashef, Inas Muen
Mirghani, Mohamed Elwathig Saeed
author_facet Hayyan, Maan
Hashim, Mohd. Ali
Al-Saadi, Mohammed A.
Hayyan, Adeeb
Alnashef, Inas Muen
Mirghani, Mohamed Elwathig Saeed
author_sort Hayyan, Maan
title Assessment of cytotoxicity and toxicity for phosphonium-based deep eutectic solvents
title_short Assessment of cytotoxicity and toxicity for phosphonium-based deep eutectic solvents
title_full Assessment of cytotoxicity and toxicity for phosphonium-based deep eutectic solvents
title_fullStr Assessment of cytotoxicity and toxicity for phosphonium-based deep eutectic solvents
title_full_unstemmed Assessment of cytotoxicity and toxicity for phosphonium-based deep eutectic solvents
title_sort assessment of cytotoxicity and toxicity for phosphonium-based deep eutectic solvents
publisher Elsevier Inc.
publishDate 2013
url http://irep.iium.edu.my/32301/
http://irep.iium.edu.my/32301/
http://irep.iium.edu.my/32301/
http://irep.iium.edu.my/32301/1/Assessment_of_cytotoxicity.pdf
first_indexed 2023-09-18T20:46:38Z
last_indexed 2023-09-18T20:46:38Z
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