Evaluation of anti-hyperlipidemia activity of Cosmos caudatus leaves in hyperlipidemic induced rat

Background : Hyperlipidemia is known as metabolic disorder in which the prevalence is increasing rapidly worldwide. The objective of this study was to evaluate the effectiveness of C. caudatus leaves in the treatment of hyperlipidemia in obese rats. The induced hyperlipidemic rats were given 200 mg...

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Main Authors:	Perumal, Vikneswari, Abdul Hamid, Azizah, Abas, Faridah, Ismail, Amin, Safinar, Intan, Shaari, Khozirah, Khatib, Alfi
Format:	Conference or Workshop Item
Language:	English English
Published:	2013
Subjects:	RS Pharmacy and materia medica
Online Access:	http://irep.iium.edu.my/32293/ http://irep.iium.edu.my/32293/ http://irep.iium.edu.my/32293/1/cover.pdf http://irep.iium.edu.my/32293/4/proceeding1.pdf

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recordtype	eprints
spelling	iium-322932013-12-16T04:47:58Z http://irep.iium.edu.my/32293/ Evaluation of anti-hyperlipidemia activity of Cosmos caudatus leaves in hyperlipidemic induced rat Perumal, Vikneswari Abdul Hamid, Azizah Abas, Faridah Ismail, Amin Safinar, Intan Shaari, Khozirah Khatib, Alfi RS Pharmacy and materia medica Background : Hyperlipidemia is known as metabolic disorder in which the prevalence is increasing rapidly worldwide. The objective of this study was to evaluate the effectiveness of C. caudatus leaves in the treatment of hyperlipidemia in obese rats. The induced hyperlipidemic rats were given 200 mg /kg BW of C. caudatus leaves ethanolic extract and 35 mg/kg BW of atorvastatin for 4 weeks. The blood was subjected for lipid profile analysis. Results : C. caudatus for 4 weeks showed a significant (P<0.05) reduced of plasma triglyceride, total cholesterol, LDL and plasma glucose, and significantly (P<0.05) increased HDL and AI value. Conclusions : This study suggests that C. caudatus is potential for the treatment of hyperlipidemia. 2013-10 Conference or Workshop Item PeerReviewed application/pdf en http://irep.iium.edu.my/32293/1/cover.pdf application/pdf en http://irep.iium.edu.my/32293/4/proceeding1.pdf Perumal, Vikneswari and Abdul Hamid, Azizah and Abas, Faridah and Ismail, Amin and Safinar, Intan and Shaari, Khozirah and Khatib, Alfi (2013) Evaluation of anti-hyperlipidemia activity of Cosmos caudatus leaves in hyperlipidemic induced rat. In: 2nd Asian Regional Conference on System Biology , 8-9 Oct 2013, Bangi. http://www.inbiosis.ukm.my/arcsb2013/
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English English
topic	RS Pharmacy and materia medica
spellingShingle	RS Pharmacy and materia medica Perumal, Vikneswari Abdul Hamid, Azizah Abas, Faridah Ismail, Amin Safinar, Intan Shaari, Khozirah Khatib, Alfi Evaluation of anti-hyperlipidemia activity of Cosmos caudatus leaves in hyperlipidemic induced rat
description	Background : Hyperlipidemia is known as metabolic disorder in which the prevalence is increasing rapidly worldwide. The objective of this study was to evaluate the effectiveness of C. caudatus leaves in the treatment of hyperlipidemia in obese rats. The induced hyperlipidemic rats were given 200 mg /kg BW of C. caudatus leaves ethanolic extract and 35 mg/kg BW of atorvastatin for 4 weeks. The blood was subjected for lipid profile analysis. Results : C. caudatus for 4 weeks showed a significant (P<0.05) reduced of plasma triglyceride, total cholesterol, LDL and plasma glucose, and significantly (P<0.05) increased HDL and AI value. Conclusions : This study suggests that C. caudatus is potential for the treatment of hyperlipidemia.
format	Conference or Workshop Item
author	Perumal, Vikneswari Abdul Hamid, Azizah Abas, Faridah Ismail, Amin Safinar, Intan Shaari, Khozirah Khatib, Alfi
author_facet	Perumal, Vikneswari Abdul Hamid, Azizah Abas, Faridah Ismail, Amin Safinar, Intan Shaari, Khozirah Khatib, Alfi
author_sort	Perumal, Vikneswari
title	Evaluation of anti-hyperlipidemia activity of Cosmos caudatus leaves in hyperlipidemic induced rat
title_short	Evaluation of anti-hyperlipidemia activity of Cosmos caudatus leaves in hyperlipidemic induced rat
title_full	Evaluation of anti-hyperlipidemia activity of Cosmos caudatus leaves in hyperlipidemic induced rat
title_fullStr	Evaluation of anti-hyperlipidemia activity of Cosmos caudatus leaves in hyperlipidemic induced rat
title_full_unstemmed	Evaluation of anti-hyperlipidemia activity of Cosmos caudatus leaves in hyperlipidemic induced rat
title_sort	evaluation of anti-hyperlipidemia activity of cosmos caudatus leaves in hyperlipidemic induced rat
publishDate	2013
url	http://irep.iium.edu.my/32293/ http://irep.iium.edu.my/32293/ http://irep.iium.edu.my/32293/1/cover.pdf http://irep.iium.edu.my/32293/4/proceeding1.pdf
first_indexed	2023-09-18T20:46:37Z
last_indexed	2023-09-18T20:46:37Z
_version_	1777409717800271872

Evaluation of anti-hyperlipidemia activity of Cosmos caudatus leaves in hyperlipidemic induced rat

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