Antioxidant, antimicrobial and total phenolic contents of Calophyllum symingtonianum

Objectives: To determine the total phenolic content, antioxidant and antimicrobial activities of the extracts from Calophyllum symingtonianum. Methods: The extracts were tested for their antioxidant activity by the DPPH radical scavenging assay and the β-carotene bleaching assay, while the anti...

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Main Authors: Nissad, Attoumani, Darnis, Deny Susanti, Bakhtiar, M. Taher
Format: Article
Language:English
Published: Coastal Life Medicine Media co., Limited 2013
Subjects:
Online Access:http://irep.iium.edu.my/32204/
http://irep.iium.edu.my/32204/
http://irep.iium.edu.my/32204/1/Journal_of_coastal_medicine.pdf
id iium-32204
recordtype eprints
spelling iium-322042018-06-12T00:31:04Z http://irep.iium.edu.my/32204/ Antioxidant, antimicrobial and total phenolic contents of Calophyllum symingtonianum Nissad, Attoumani Darnis, Deny Susanti Bakhtiar, M. Taher RS Pharmacy and materia medica Objectives: To determine the total phenolic content, antioxidant and antimicrobial activities of the extracts from Calophyllum symingtonianum. Methods: The extracts were tested for their antioxidant activity by the DPPH radical scavenging assay and the β-carotene bleaching assay, while the antimicrobial activity was determined by disc diffusion method. Results: All the tested extracts showed antioxidant and antimicrobial properties. The extracts showed moderate antimicrobial activity against S. aureus with zone of inhibition values of 10, 11 and 12 mm for n-hexane, DCM and methanol extracts respectively at 30 µg/disc. n-Hexane showed low antimicrobial activity against P. aeruginosa (5 mm) at 30 µg/disc. The total phenolic test showed that methanol has high phenolic content (162.25 mg GAE/g of extract) compared to the other extracts. Conclusion: The ability of the extracts to inhibit microbial growth at a concentration of 30 µg/disc indicated the its potent antimicrobial activity. Coastal Life Medicine Media co., Limited 2013 Article PeerReviewed application/pdf en http://irep.iium.edu.my/32204/1/Journal_of_coastal_medicine.pdf Nissad, Attoumani and Darnis, Deny Susanti and Bakhtiar, M. Taher (2013) Antioxidant, antimicrobial and total phenolic contents of Calophyllum symingtonianum. Journal of Coastal Life Medicine, 3 (2). pp. 1-5. ISSN 2309-6152 (O), 2309-5288 (P) http://jclmm.net/20131.htm
repository_type Digital Repository
institution_category Local University
institution International Islamic University Malaysia
building IIUM Repository
collection Online Access
language English
topic RS Pharmacy and materia medica
spellingShingle RS Pharmacy and materia medica
Nissad, Attoumani
Darnis, Deny Susanti
Bakhtiar, M. Taher
Antioxidant, antimicrobial and total phenolic contents of Calophyllum symingtonianum
description Objectives: To determine the total phenolic content, antioxidant and antimicrobial activities of the extracts from Calophyllum symingtonianum. Methods: The extracts were tested for their antioxidant activity by the DPPH radical scavenging assay and the β-carotene bleaching assay, while the antimicrobial activity was determined by disc diffusion method. Results: All the tested extracts showed antioxidant and antimicrobial properties. The extracts showed moderate antimicrobial activity against S. aureus with zone of inhibition values of 10, 11 and 12 mm for n-hexane, DCM and methanol extracts respectively at 30 µg/disc. n-Hexane showed low antimicrobial activity against P. aeruginosa (5 mm) at 30 µg/disc. The total phenolic test showed that methanol has high phenolic content (162.25 mg GAE/g of extract) compared to the other extracts. Conclusion: The ability of the extracts to inhibit microbial growth at a concentration of 30 µg/disc indicated the its potent antimicrobial activity.
format Article
author Nissad, Attoumani
Darnis, Deny Susanti
Bakhtiar, M. Taher
author_facet Nissad, Attoumani
Darnis, Deny Susanti
Bakhtiar, M. Taher
author_sort Nissad, Attoumani
title Antioxidant, antimicrobial and total phenolic contents of Calophyllum symingtonianum
title_short Antioxidant, antimicrobial and total phenolic contents of Calophyllum symingtonianum
title_full Antioxidant, antimicrobial and total phenolic contents of Calophyllum symingtonianum
title_fullStr Antioxidant, antimicrobial and total phenolic contents of Calophyllum symingtonianum
title_full_unstemmed Antioxidant, antimicrobial and total phenolic contents of Calophyllum symingtonianum
title_sort antioxidant, antimicrobial and total phenolic contents of calophyllum symingtonianum
publisher Coastal Life Medicine Media co., Limited
publishDate 2013
url http://irep.iium.edu.my/32204/
http://irep.iium.edu.my/32204/
http://irep.iium.edu.my/32204/1/Journal_of_coastal_medicine.pdf
first_indexed 2023-09-18T20:46:29Z
last_indexed 2023-09-18T20:46:29Z
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