Back pain and osteolysis of the thoracic spine in an adult: a case of monostotic fibrous dysplasia masquerading as spinal metastasis

Isolated involvement of vertebra with fibrous dysplasia is rarely seen. We present a case of a 53 year old lady who presented with an 8-month history of pain in the thoracic region with paraparesis which required assistance for ambulation. She had a history of papillary thyroid carcinoma underwent t...

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Main Authors:	Zakaria@Mohamad, Zamzuri, Sharifudin, Mohd Ariff, Mohamed Amin, Mohamed Azril, Abd. Aziz, Azian, Khan, Ed Simor, Goh, Kian Liang
Format:	Conference or Workshop Item
Language:	English English
Published:	2013
Subjects:	RB Pathology RC0254 Neoplasms. Tumors. Oncology (including Cancer) RD701 Orthopedics
Online Access:	http://irep.iium.edu.my/31837/ http://irep.iium.edu.my/31837/ http://irep.iium.edu.my/31837/1/APOA_2013_-_Spinal_Fibrous_Dysplasia_-_Dr_Ariff.pdf http://irep.iium.edu.my/31837/17/Back_Pain_and_Osteolysis_of_the_Thoracic_Spine_in_an_Adult_%E2%80%93_a_Case_of_Monostotic_Fibrous_Dysplasia_Masquerading_as_Spinal_Metastasis.pdf

id	iium-31837
recordtype	eprints
spelling	iium-318372018-12-20T00:11:04Z http://irep.iium.edu.my/31837/ Back pain and osteolysis of the thoracic spine in an adult: a case of monostotic fibrous dysplasia masquerading as spinal metastasis Zakaria@Mohamad, Zamzuri Sharifudin, Mohd Ariff Mohamed Amin, Mohamed Azril Abd. Aziz, Azian Khan, Ed Simor Goh, Kian Liang RB Pathology RC0254 Neoplasms. Tumors. Oncology (including Cancer) RD701 Orthopedics Isolated involvement of vertebra with fibrous dysplasia is rarely seen. We present a case of a 53 year old lady who presented with an 8-month history of pain in the thoracic region with paraparesis which required assistance for ambulation. She had a history of papillary thyroid carcinoma underwent total thyroidectomy 1 year prior to her current problem. MR imaging revealed isolated osteolytic lesion over posterior element of T12 vertebra with narrowing of the spinal canal causing compression to the cord. CT-guided biopsy did not obtain any malignant cells. Patient underwent posterior decompression with fusion and stabilization between T10 to L2 with pedicle screw system. Posterior element of T12 and bilateral erector spinae muscles sent for histopathological evaluation. The diagnosis of fibrous dysplasia was made histologically. Five months post-surgery, the patient’s condition improved gradually. Fibrous dysplasia occurs rarely in axial bones than peripheral bones. This case illustrate that osteolytic lesion of the vertebrae should be evaluated with detailed radiological and histopathological examination before an empirical diagnosis of spinal metastasis is made in an adult with a background history of primary malignancy well-known to spread to the bone. 2013-08-29 Conference or Workshop Item PeerReviewed application/pdf en http://irep.iium.edu.my/31837/1/APOA_2013_-_Spinal_Fibrous_Dysplasia_-_Dr_Ariff.pdf application/pdf en http://irep.iium.edu.my/31837/17/Back_Pain_and_Osteolysis_of_the_Thoracic_Spine_in_an_Adult_%E2%80%93_a_Case_of_Monostotic_Fibrous_Dysplasia_Masquerading_as_Spinal_Metastasis.pdf Zakaria@Mohamad, Zamzuri and Sharifudin, Mohd Ariff and Mohamed Amin, Mohamed Azril and Abd. Aziz, Azian and Khan, Ed Simor and Goh, Kian Liang (2013) Back pain and osteolysis of the thoracic spine in an adult: a case of monostotic fibrous dysplasia masquerading as spinal metastasis. In: 9th Asia Pacific Spine Society Congress, 29-31 Aug 2013, Pullman Kuching, Sarawak, Malaysia. http://www.apoa2013.org/
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English English
topic	RB Pathology RC0254 Neoplasms. Tumors. Oncology (including Cancer) RD701 Orthopedics
spellingShingle	RB Pathology RC0254 Neoplasms. Tumors. Oncology (including Cancer) RD701 Orthopedics Zakaria@Mohamad, Zamzuri Sharifudin, Mohd Ariff Mohamed Amin, Mohamed Azril Abd. Aziz, Azian Khan, Ed Simor Goh, Kian Liang Back pain and osteolysis of the thoracic spine in an adult: a case of monostotic fibrous dysplasia masquerading as spinal metastasis
description	Isolated involvement of vertebra with fibrous dysplasia is rarely seen. We present a case of a 53 year old lady who presented with an 8-month history of pain in the thoracic region with paraparesis which required assistance for ambulation. She had a history of papillary thyroid carcinoma underwent total thyroidectomy 1 year prior to her current problem. MR imaging revealed isolated osteolytic lesion over posterior element of T12 vertebra with narrowing of the spinal canal causing compression to the cord. CT-guided biopsy did not obtain any malignant cells. Patient underwent posterior decompression with fusion and stabilization between T10 to L2 with pedicle screw system. Posterior element of T12 and bilateral erector spinae muscles sent for histopathological evaluation. The diagnosis of fibrous dysplasia was made histologically. Five months post-surgery, the patient’s condition improved gradually. Fibrous dysplasia occurs rarely in axial bones than peripheral bones. This case illustrate that osteolytic lesion of the vertebrae should be evaluated with detailed radiological and histopathological examination before an empirical diagnosis of spinal metastasis is made in an adult with a background history of primary malignancy well-known to spread to the bone.
format	Conference or Workshop Item
author	Zakaria@Mohamad, Zamzuri Sharifudin, Mohd Ariff Mohamed Amin, Mohamed Azril Abd. Aziz, Azian Khan, Ed Simor Goh, Kian Liang
author_facet	Zakaria@Mohamad, Zamzuri Sharifudin, Mohd Ariff Mohamed Amin, Mohamed Azril Abd. Aziz, Azian Khan, Ed Simor Goh, Kian Liang
author_sort	Zakaria@Mohamad, Zamzuri
title	Back pain and osteolysis of the thoracic spine in an adult: a case of monostotic fibrous dysplasia masquerading as spinal metastasis
title_short	Back pain and osteolysis of the thoracic spine in an adult: a case of monostotic fibrous dysplasia masquerading as spinal metastasis
title_full	Back pain and osteolysis of the thoracic spine in an adult: a case of monostotic fibrous dysplasia masquerading as spinal metastasis
title_fullStr	Back pain and osteolysis of the thoracic spine in an adult: a case of monostotic fibrous dysplasia masquerading as spinal metastasis
title_full_unstemmed	Back pain and osteolysis of the thoracic spine in an adult: a case of monostotic fibrous dysplasia masquerading as spinal metastasis
title_sort	back pain and osteolysis of the thoracic spine in an adult: a case of monostotic fibrous dysplasia masquerading as spinal metastasis
publishDate	2013
url	http://irep.iium.edu.my/31837/ http://irep.iium.edu.my/31837/ http://irep.iium.edu.my/31837/1/APOA_2013_-_Spinal_Fibrous_Dysplasia_-_Dr_Ariff.pdf http://irep.iium.edu.my/31837/17/Back_Pain_and_Osteolysis_of_the_Thoracic_Spine_in_an_Adult_%E2%80%93_a_Case_of_Monostotic_Fibrous_Dysplasia_Masquerading_as_Spinal_Metastasis.pdf
first_indexed	2023-09-18T20:46:00Z
last_indexed	2023-09-18T20:46:00Z
_version_	1777409678748155904

Back pain and osteolysis of the thoracic spine in an adult: a case of monostotic fibrous dysplasia masquerading as spinal metastasis

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