Transcriptional regulation of tumour necrosis factor-related apoptosis-inducing ligand

Tumour necrosis factor-related apoptosis-inducing ligand (TRAIL) has dual functions mediating both apoptosis and survival of cells. This review focusses on the current regulatory factors that control TRAIL transcription. Here, we also highlight the role of distinct transcription factors that co-oper...

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Main Authors:	Md. Azahri, Nor Saadah, Kavurma, Mary M.
Format:	Article
Language:	English
Published:	Birkhauser Verlag Basel 2013
Subjects:	Q Science (General)
Online Access:	http://irep.iium.edu.my/31734/ http://irep.iium.edu.my/31734/ http://irep.iium.edu.my/31734/ http://irep.iium.edu.my/31734/1/tumour.pdf

id	iium-31734
recordtype	eprints
spelling	iium-317342014-07-14T07:40:17Z http://irep.iium.edu.my/31734/ Transcriptional regulation of tumour necrosis factor-related apoptosis-inducing ligand Md. Azahri, Nor Saadah Kavurma, Mary M. Q Science (General) Tumour necrosis factor-related apoptosis-inducing ligand (TRAIL) has dual functions mediating both apoptosis and survival of cells. This review focusses on the current regulatory factors that control TRAIL transcription. Here, we also highlight the role of distinct transcription factors that co-operate and regulate TRAIL in different pathological states. A better understanding of the molecular signalling pathways of TRAIL-induced cell death and survival in disease may lead to more sophisticated technologies for novel therapeutic targets. © 2013 Springer Basel. Birkhauser Verlag Basel 2013 Article PeerReviewed application/pdf en http://irep.iium.edu.my/31734/1/tumour.pdf Md. Azahri, Nor Saadah and Kavurma, Mary M. (2013) Transcriptional regulation of tumour necrosis factor-related apoptosis-inducing ligand. Cellular and Molecular Life Sciences, 70 (19). pp. 3617-3629. ISSN 1420-682X http://dx.doi.org/10.1007/s00018-013-1264-x doi:10.1007/s00018-013-1264-x
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English
topic	Q Science (General)
spellingShingle	Q Science (General) Md. Azahri, Nor Saadah Kavurma, Mary M. Transcriptional regulation of tumour necrosis factor-related apoptosis-inducing ligand
description	Tumour necrosis factor-related apoptosis-inducing ligand (TRAIL) has dual functions mediating both apoptosis and survival of cells. This review focusses on the current regulatory factors that control TRAIL transcription. Here, we also highlight the role of distinct transcription factors that co-operate and regulate TRAIL in different pathological states. A better understanding of the molecular signalling pathways of TRAIL-induced cell death and survival in disease may lead to more sophisticated technologies for novel therapeutic targets. © 2013 Springer Basel.
format	Article
author	Md. Azahri, Nor Saadah Kavurma, Mary M.
author_facet	Md. Azahri, Nor Saadah Kavurma, Mary M.
author_sort	Md. Azahri, Nor Saadah
title	Transcriptional regulation of tumour necrosis factor-related apoptosis-inducing ligand
title_short	Transcriptional regulation of tumour necrosis factor-related apoptosis-inducing ligand
title_full	Transcriptional regulation of tumour necrosis factor-related apoptosis-inducing ligand
title_fullStr	Transcriptional regulation of tumour necrosis factor-related apoptosis-inducing ligand
title_full_unstemmed	Transcriptional regulation of tumour necrosis factor-related apoptosis-inducing ligand
title_sort	transcriptional regulation of tumour necrosis factor-related apoptosis-inducing ligand
publisher	Birkhauser Verlag Basel
publishDate	2013
url	http://irep.iium.edu.my/31734/ http://irep.iium.edu.my/31734/ http://irep.iium.edu.my/31734/ http://irep.iium.edu.my/31734/1/tumour.pdf
first_indexed	2023-09-18T20:45:52Z
last_indexed	2023-09-18T20:45:52Z
_version_	1777409670860767232

Transcriptional regulation of tumour necrosis factor-related apoptosis-inducing ligand

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