Study of cytological changes in normal appearing oral mucosa of smokers

Objective: To investigate the cytopathological effects of smoking in normal appearing oral mucosa of smokers namely, inflammation, hyperkeratinisation and dysplasia and to compare with the cytological smear of non-smokers. Materials and methods: Oral smears were obtained from the side of the tongu...

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Main Author:	Faisal, Ghasak Ghazi
Format:	Conference or Workshop Item
Language:	English
Published:	2013
Subjects:	R Medicine (General) RB Pathology RK Dentistry
Online Access:	http://irep.iium.edu.my/31461/ http://irep.iium.edu.my/31461/ http://irep.iium.edu.my/31461/1/IREE_2013_poster.pdf

id	iium-31461
recordtype	eprints
spelling	iium-314612013-09-27T04:03:37Z http://irep.iium.edu.my/31461/ Study of cytological changes in normal appearing oral mucosa of smokers Faisal, Ghasak Ghazi R Medicine (General) RB Pathology RK Dentistry Objective: To investigate the cytopathological effects of smoking in normal appearing oral mucosa of smokers namely, inflammation, hyperkeratinisation and dysplasia and to compare with the cytological smear of non-smokers. Materials and methods: Oral smears were obtained from the side of the tongue and floor of the mouth of 40 smokers with normal oral mucosa and 40 non-smokers were used as controls. Two samples have been collected from each patient by Cytobrush. The smears were histochemically stained by Papanicolaou stain and examined under light microscope for the mentioned cytological changes. Results: The smokers group showed 63% inflammation, 26% mild dysplasia and 36% hyperkeratinisation. The control group showed 35% inflammation, 2% mild dysplasia and 12% hyperkeratinisation. There was a statistically significant difference in the presence of inflammation, hyperkeratinisation and dysplasia (P<0.005) between the smokers and non-smokers groups. Conclusion: Brush biopsy screening can be used in clinic as adjunct in the early diagnosis of premalignant changes that can help prevent the occurrence of oral squamous cell carcinoma. The procedure is fast, painless and inexpensive. 2013 Conference or Workshop Item PeerReviewed application/pdf en http://irep.iium.edu.my/31461/1/IREE_2013_poster.pdf Faisal, Ghasak Ghazi (2013) Study of cytological changes in normal appearing oral mucosa of smokers. In: IIUM Research, Invention and Innovation Exhibition (IRIIE) 2013, 19-20th February 2013, Cultural Activity Centre (CAC) and KAED Gallery, IIUM. http://www.iium.edu.my/irie/13/index.php/component/content/?view=featured
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English
topic	R Medicine (General) RB Pathology RK Dentistry
spellingShingle	R Medicine (General) RB Pathology RK Dentistry Faisal, Ghasak Ghazi Study of cytological changes in normal appearing oral mucosa of smokers
description	Objective: To investigate the cytopathological effects of smoking in normal appearing oral mucosa of smokers namely, inflammation, hyperkeratinisation and dysplasia and to compare with the cytological smear of non-smokers. Materials and methods: Oral smears were obtained from the side of the tongue and floor of the mouth of 40 smokers with normal oral mucosa and 40 non-smokers were used as controls. Two samples have been collected from each patient by Cytobrush. The smears were histochemically stained by Papanicolaou stain and examined under light microscope for the mentioned cytological changes. Results: The smokers group showed 63% inflammation, 26% mild dysplasia and 36% hyperkeratinisation. The control group showed 35% inflammation, 2% mild dysplasia and 12% hyperkeratinisation. There was a statistically significant difference in the presence of inflammation, hyperkeratinisation and dysplasia (P<0.005) between the smokers and non-smokers groups. Conclusion: Brush biopsy screening can be used in clinic as adjunct in the early diagnosis of premalignant changes that can help prevent the occurrence of oral squamous cell carcinoma. The procedure is fast, painless and inexpensive.
format	Conference or Workshop Item
author	Faisal, Ghasak Ghazi
author_facet	Faisal, Ghasak Ghazi
author_sort	Faisal, Ghasak Ghazi
title	Study of cytological changes in normal appearing oral mucosa of smokers
title_short	Study of cytological changes in normal appearing oral mucosa of smokers
title_full	Study of cytological changes in normal appearing oral mucosa of smokers
title_fullStr	Study of cytological changes in normal appearing oral mucosa of smokers
title_full_unstemmed	Study of cytological changes in normal appearing oral mucosa of smokers
title_sort	study of cytological changes in normal appearing oral mucosa of smokers
publishDate	2013
url	http://irep.iium.edu.my/31461/ http://irep.iium.edu.my/31461/ http://irep.iium.edu.my/31461/1/IREE_2013_poster.pdf
first_indexed	2023-09-18T20:45:40Z
last_indexed	2023-09-18T20:45:40Z
_version_	1777409657545949184

Study of cytological changes in normal appearing oral mucosa of smokers

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