Gender differences in fasting serum leptin level among Malaysian population

Serum leptin increases with progressive obesity in both genders. However, for any given measure of obesity, leptin levels are higher in women than men. This research is to study the gender differences of the fasting plasma leptin concentration in Malaysian people from east coast Malaysia with a ba...

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Main Authors:	Abdulwahab, Dalia F, Ezzat Mustafa, Basma, Abbas, Abdul Razaq, Mustafa, Nazih Shaban, Y., Osama, Ramli, Roszaman
Format:	Conference or Workshop Item
Language:	English English English English English
Published:	2013
Subjects:	RG Gynecology and obstetrics
Online Access:	http://irep.iium.edu.my/31325/ http://irep.iium.edu.my/31325/1/Gender_differences_in_serum_Leptin_level__in_Malaysian_people.pdf http://irep.iium.edu.my/31325/5/Gender_differences_in_fasting_serum_Leptin_level__among_%282%29.pdf http://irep.iium.edu.my/31325/9/dalia_reciept.jpeg http://irep.iium.edu.my/31325/10/drdalia592013.pdf http://irep.iium.edu.my/31325/15/MRMC2013_Abstract_Submission_%281%29_DaliaF.pdf

id	iium-31325
recordtype	eprints
spelling	iium-313252013-09-06T09:06:21Z http://irep.iium.edu.my/31325/ Gender differences in fasting serum leptin level among Malaysian population Abdulwahab, Dalia F Ezzat Mustafa, Basma Abbas, Abdul Razaq Mustafa, Nazih Shaban Y., Osama Ramli, Roszaman RG Gynecology and obstetrics Serum leptin increases with progressive obesity in both genders. However, for any given measure of obesity, leptin levels are higher in women than men. This research is to study the gender differences of the fasting plasma leptin concentration in Malaysian people from east coast Malaysia with a back ground knowledge of ethnic variation. To be as a baseline for future research, and to consolidate our knowledge regarding leptin and it’s correlation with endocrine disorders. Objective: To study the gender differences of the plasma leptin and its relationship to the ethnic group, so that can establish a base line for future studies regarding leptin hormone and it’s association with different endocrine and fertility issues Method: This was a cross sectional study included 100 consented Malaysian people(50 male and female) were recruited from Kulliyyah of dentistry, International Islamic University Malaysia and medical department, Hospital Tengku Ampuan Afzan, Kuantan, those with endocrine, diabetic illness, abnormal BMI, chronic illness and any patient on hormonal treatment were excluded from the study. Individual venous blood was taken between 0800–0900 am after an overnight fasting. Determination of serum leptin was done by enzyme linked immune-sorbent assay (ELISA)and measured in ng/ml. Data were analyzed using SPSS 18 Result:. Mean age were, 34.5±6.4 and 31.2± 4.3 for male and female respectively, there was no significant difference between the age of both groups. Mean body mass index for male was 23 ± 1.91 Kg / m2 which were not significantly different from the female BMI which was 22 ± 0.87 Kg / m2. data were analysed by Mann-Whitney U-test, found that serum leptin levels in females are significantly higher (Z= 6.0, p<0.001) than those in males, 7.29 ng/ml vs 3.94 ng/ml respectively. Correlation coefficient of serum leptin level with female body mass index (kg/m2) is 0.693 in a value of <.0001 conclusion: Serum leptin is significantly affected by gender, with women have significantly higher serum leptin level than man, further study is required to measure the fat mass in addition to serum leptin in both genders as a possible reason for this difference,. Keywords LEPTIN , GENDER, Ethnic variation 2013 Conference or Workshop Item PeerReviewed application/pdf en http://irep.iium.edu.my/31325/1/Gender_differences_in_serum_Leptin_level__in_Malaysian_people.pdf application/pdf en http://irep.iium.edu.my/31325/5/Gender_differences_in_fasting_serum_Leptin_level__among_%282%29.pdf application/pdf en http://irep.iium.edu.my/31325/9/dalia_reciept.jpeg application/pdf en http://irep.iium.edu.my/31325/10/drdalia592013.pdf application/pdf en http://irep.iium.edu.my/31325/15/MRMC2013_Abstract_Submission_%281%29_DaliaF.pdf Abdulwahab, Dalia F and Ezzat Mustafa, Basma and Abbas, Abdul Razaq and Mustafa, Nazih Shaban and Y., Osama and Ramli, Roszaman (2013) Gender differences in fasting serum leptin level among Malaysian population. In: MRMC 3rd Malaysian Reproductive Medicine Congress, 17th-19th April 2013, Kuala Lumpur Convention Centre. (Unpublished)
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English English English English English
topic	RG Gynecology and obstetrics
spellingShingle	RG Gynecology and obstetrics Abdulwahab, Dalia F Ezzat Mustafa, Basma Abbas, Abdul Razaq Mustafa, Nazih Shaban Y., Osama Ramli, Roszaman Gender differences in fasting serum leptin level among Malaysian population
description	Serum leptin increases with progressive obesity in both genders. However, for any given measure of obesity, leptin levels are higher in women than men. This research is to study the gender differences of the fasting plasma leptin concentration in Malaysian people from east coast Malaysia with a back ground knowledge of ethnic variation. To be as a baseline for future research, and to consolidate our knowledge regarding leptin and it’s correlation with endocrine disorders. Objective: To study the gender differences of the plasma leptin and its relationship to the ethnic group, so that can establish a base line for future studies regarding leptin hormone and it’s association with different endocrine and fertility issues Method: This was a cross sectional study included 100 consented Malaysian people(50 male and female) were recruited from Kulliyyah of dentistry, International Islamic University Malaysia and medical department, Hospital Tengku Ampuan Afzan, Kuantan, those with endocrine, diabetic illness, abnormal BMI, chronic illness and any patient on hormonal treatment were excluded from the study. Individual venous blood was taken between 0800–0900 am after an overnight fasting. Determination of serum leptin was done by enzyme linked immune-sorbent assay (ELISA)and measured in ng/ml. Data were analyzed using SPSS 18 Result:. Mean age were, 34.5±6.4 and 31.2± 4.3 for male and female respectively, there was no significant difference between the age of both groups. Mean body mass index for male was 23 ± 1.91 Kg / m2 which were not significantly different from the female BMI which was 22 ± 0.87 Kg / m2. data were analysed by Mann-Whitney U-test, found that serum leptin levels in females are significantly higher (Z= 6.0, p<0.001) than those in males, 7.29 ng/ml vs 3.94 ng/ml respectively. Correlation coefficient of serum leptin level with female body mass index (kg/m2) is 0.693 in a value of <.0001 conclusion: Serum leptin is significantly affected by gender, with women have significantly higher serum leptin level than man, further study is required to measure the fat mass in addition to serum leptin in both genders as a possible reason for this difference,. Keywords LEPTIN , GENDER, Ethnic variation
format	Conference or Workshop Item
author	Abdulwahab, Dalia F Ezzat Mustafa, Basma Abbas, Abdul Razaq Mustafa, Nazih Shaban Y., Osama Ramli, Roszaman
author_facet	Abdulwahab, Dalia F Ezzat Mustafa, Basma Abbas, Abdul Razaq Mustafa, Nazih Shaban Y., Osama Ramli, Roszaman
author_sort	Abdulwahab, Dalia F
title	Gender differences in fasting serum leptin level among Malaysian population
title_short	Gender differences in fasting serum leptin level among Malaysian population
title_full	Gender differences in fasting serum leptin level among Malaysian population
title_fullStr	Gender differences in fasting serum leptin level among Malaysian population
title_full_unstemmed	Gender differences in fasting serum leptin level among Malaysian population
title_sort	gender differences in fasting serum leptin level among malaysian population
publishDate	2013
url	http://irep.iium.edu.my/31325/ http://irep.iium.edu.my/31325/1/Gender_differences_in_serum_Leptin_level__in_Malaysian_people.pdf http://irep.iium.edu.my/31325/5/Gender_differences_in_fasting_serum_Leptin_level__among_%282%29.pdf http://irep.iium.edu.my/31325/9/dalia_reciept.jpeg http://irep.iium.edu.my/31325/10/drdalia592013.pdf http://irep.iium.edu.my/31325/15/MRMC2013_Abstract_Submission_%281%29_DaliaF.pdf
first_indexed	2023-09-18T20:45:33Z
last_indexed	2023-09-18T20:45:33Z
_version_	1777409650388369408

Gender differences in fasting serum leptin level among Malaysian population

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