In vitro antimicrobial and cytotoxic activity of Tamarix dioica Roxb. leaves

Medicinal plants have been in use for thousands of years for treatment of different types of diseases and a large inventory of useful drugs has been isolated from them. The aim of our study is to investigate a new and effective plant possessing antimicrobial activity. The crude extracts of Tamarix...

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Main Authors: Khan, Saifullah, Ullah, Farman, Mahmood, Tahir
Format: Article
Language:English
Published: TUBITAK Scientific & Technical Research Council Turkey 2013
Subjects:
Online Access:http://irep.iium.edu.my/30335/
http://irep.iium.edu.my/30335/
http://irep.iium.edu.my/30335/
http://irep.iium.edu.my/30335/1/n_vitro_antimicrobial.pdf
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spelling iium-303352013-07-16T01:28:38Z http://irep.iium.edu.my/30335/ In vitro antimicrobial and cytotoxic activity of Tamarix dioica Roxb. leaves Khan, Saifullah Ullah, Farman Mahmood, Tahir RS Pharmacy and materia medica Medicinal plants have been in use for thousands of years for treatment of different types of diseases and a large inventory of useful drugs has been isolated from them. The aim of our study is to investigate a new and effective plant possessing antimicrobial activity. The crude extracts of Tamarix dioica Roxb. leaves, as well as fractions of the extract in various solvents, were investigated against standard strains of bacteria Pseudomonas aeruginosa, Escherichia coli, Klebsiella pneumoniae, Shigella flexneri, Bacillus subtilis, Salmonella typhi, and Staphylococcus aureus and fungi Candida glabrata, Aspergillus niger, Trichophyton rubrum, Candida tropicalis, and Aspergillus fumigatus. For in vitro antibacterial and antifungal studies of T. dioica extracts, the agar well diffusion technique was used. For cytotoxic study, brine shrimp (Artemia salina) larvae were used. Results of the crude extract and some fractionated samples showed significant antifungal properties, but low antibacterial response and negligible cytotoxic activity. It was recognized that Tamarix dioica has the potential for future development of new antifungal drugs/medicine. TUBITAK Scientific & Technical Research Council Turkey 2013-05-16 Article PeerReviewed application/pdf en http://irep.iium.edu.my/30335/1/n_vitro_antimicrobial.pdf Khan, Saifullah and Ullah, Farman and Mahmood, Tahir (2013) In vitro antimicrobial and cytotoxic activity of Tamarix dioica Roxb. leaves. Turkish Journal of Biology, 37 (3). pp. 329-335. ISSN 1300-0152 http://journals.tubitak.gov.tr/biology/issues/biy-13-37-3/biy-37-3-11-1204-18.pdf 10.3906/biy-1204-18
repository_type Digital Repository
institution_category Local University
institution International Islamic University Malaysia
building IIUM Repository
collection Online Access
language English
topic RS Pharmacy and materia medica
spellingShingle RS Pharmacy and materia medica
Khan, Saifullah
Ullah, Farman
Mahmood, Tahir
In vitro antimicrobial and cytotoxic activity of Tamarix dioica Roxb. leaves
description Medicinal plants have been in use for thousands of years for treatment of different types of diseases and a large inventory of useful drugs has been isolated from them. The aim of our study is to investigate a new and effective plant possessing antimicrobial activity. The crude extracts of Tamarix dioica Roxb. leaves, as well as fractions of the extract in various solvents, were investigated against standard strains of bacteria Pseudomonas aeruginosa, Escherichia coli, Klebsiella pneumoniae, Shigella flexneri, Bacillus subtilis, Salmonella typhi, and Staphylococcus aureus and fungi Candida glabrata, Aspergillus niger, Trichophyton rubrum, Candida tropicalis, and Aspergillus fumigatus. For in vitro antibacterial and antifungal studies of T. dioica extracts, the agar well diffusion technique was used. For cytotoxic study, brine shrimp (Artemia salina) larvae were used. Results of the crude extract and some fractionated samples showed significant antifungal properties, but low antibacterial response and negligible cytotoxic activity. It was recognized that Tamarix dioica has the potential for future development of new antifungal drugs/medicine.
format Article
author Khan, Saifullah
Ullah, Farman
Mahmood, Tahir
author_facet Khan, Saifullah
Ullah, Farman
Mahmood, Tahir
author_sort Khan, Saifullah
title In vitro antimicrobial and cytotoxic activity of Tamarix dioica Roxb. leaves
title_short In vitro antimicrobial and cytotoxic activity of Tamarix dioica Roxb. leaves
title_full In vitro antimicrobial and cytotoxic activity of Tamarix dioica Roxb. leaves
title_fullStr In vitro antimicrobial and cytotoxic activity of Tamarix dioica Roxb. leaves
title_full_unstemmed In vitro antimicrobial and cytotoxic activity of Tamarix dioica Roxb. leaves
title_sort in vitro antimicrobial and cytotoxic activity of tamarix dioica roxb. leaves
publisher TUBITAK Scientific & Technical Research Council Turkey
publishDate 2013
url http://irep.iium.edu.my/30335/
http://irep.iium.edu.my/30335/
http://irep.iium.edu.my/30335/
http://irep.iium.edu.my/30335/1/n_vitro_antimicrobial.pdf
first_indexed 2023-09-18T20:44:29Z
last_indexed 2023-09-18T20:44:29Z
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