Are deep eutectic solvents benign or toxic?

In continuation of investigation for environmentally benign protocol for new solvents termed deep eutectic solvents (DESs), it is herein reported results concerning the toxicity and cytotoxicity of choline chloride (ChCl) based DESs with four hydrogen bond donors including glycerine, ethylene glycol...

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Main Authors:	Hayyan, Maan, Hashim, Mohd Ali, Hayyan, Adeeb, Al-Saadi, Mohammed A., Alnashef, Inas Muen, Mirghani, Mohamed Elwathig Saeed, Saheed, Olorunnisola Kola
Format:	Article
Language:	English
Published:	Elsevier Inc. 2013
Subjects:	TD Environmental technology. Sanitary engineering
Online Access:	http://irep.iium.edu.my/29509/ http://irep.iium.edu.my/29509/ http://irep.iium.edu.my/29509/ http://irep.iium.edu.my/29509/1/CHEM13334.pdf

id	iium-29509
recordtype	eprints
spelling	iium-295092013-05-27T06:24:27Z http://irep.iium.edu.my/29509/ Are deep eutectic solvents benign or toxic? Hayyan, Maan Hashim, Mohd Ali Hayyan, Adeeb Al-Saadi, Mohammed A. Alnashef, Inas Muen Mirghani, Mohamed Elwathig Saeed Saheed, Olorunnisola Kola TD Environmental technology. Sanitary engineering In continuation of investigation for environmentally benign protocol for new solvents termed deep eutectic solvents (DESs), it is herein reported results concerning the toxicity and cytotoxicity of choline chloride (ChCl) based DESs with four hydrogen bond donors including glycerine, ethylene glycol, triethylene glycol and urea. The toxicity was investigated using two Gram positive bacteria Bacillus subtilis and Staphylococcus aureus, and two Gram negative bacteria Escherichia coli and Pseudomonas aeruginosa. The cytotoxicity effect was tested using the Artemia salina leach. It was found that there was no toxic effect for the tested DESs on all of the studied bacteria confirming their benign effects on these bacteria. Nevertheless, it was found that the cytotoxicity of DESs was much higher than their individual components (e.g. glycerine, ChCl) indicating that their toxicological behavior is different. For our best knowledge this is the first time that toxicity and cytotoxicity of DESs were studied. The toxicity and cytotoxicity of DESs varied depending on the structure of components. Careful usage of the terms non-toxicity and biodegradability must be considered. More investigation on this matter is required. Elsevier Inc. 2013-02 Article PeerReviewed application/pdf en http://irep.iium.edu.my/29509/1/CHEM13334.pdf Hayyan, Maan and Hashim, Mohd Ali and Hayyan, Adeeb and Al-Saadi, Mohammed A. and Alnashef, Inas Muen and Mirghani, Mohamed Elwathig Saeed and Saheed, Olorunnisola Kola (2013) Are deep eutectic solvents benign or toxic? Chemosphere, 90 (7). pp. 2193-2195. ISSN 0045-6535 http://www.sciencedirect.com/science/article/pii/S0045653512013513 10.1016/j.chemosphere.2012.11.004
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English
topic	TD Environmental technology. Sanitary engineering
spellingShingle	TD Environmental technology. Sanitary engineering Hayyan, Maan Hashim, Mohd Ali Hayyan, Adeeb Al-Saadi, Mohammed A. Alnashef, Inas Muen Mirghani, Mohamed Elwathig Saeed Saheed, Olorunnisola Kola Are deep eutectic solvents benign or toxic?
description	In continuation of investigation for environmentally benign protocol for new solvents termed deep eutectic solvents (DESs), it is herein reported results concerning the toxicity and cytotoxicity of choline chloride (ChCl) based DESs with four hydrogen bond donors including glycerine, ethylene glycol, triethylene glycol and urea. The toxicity was investigated using two Gram positive bacteria Bacillus subtilis and Staphylococcus aureus, and two Gram negative bacteria Escherichia coli and Pseudomonas aeruginosa. The cytotoxicity effect was tested using the Artemia salina leach. It was found that there was no toxic effect for the tested DESs on all of the studied bacteria confirming their benign effects on these bacteria. Nevertheless, it was found that the cytotoxicity of DESs was much higher than their individual components (e.g. glycerine, ChCl) indicating that their toxicological behavior is different. For our best knowledge this is the first time that toxicity and cytotoxicity of DESs were studied. The toxicity and cytotoxicity of DESs varied depending on the structure of components. Careful usage of the terms non-toxicity and biodegradability must be considered. More investigation on this matter is required.
format	Article
author	Hayyan, Maan Hashim, Mohd Ali Hayyan, Adeeb Al-Saadi, Mohammed A. Alnashef, Inas Muen Mirghani, Mohamed Elwathig Saeed Saheed, Olorunnisola Kola
author_facet	Hayyan, Maan Hashim, Mohd Ali Hayyan, Adeeb Al-Saadi, Mohammed A. Alnashef, Inas Muen Mirghani, Mohamed Elwathig Saeed Saheed, Olorunnisola Kola
author_sort	Hayyan, Maan
title	Are deep eutectic solvents benign or toxic?
title_short	Are deep eutectic solvents benign or toxic?
title_full	Are deep eutectic solvents benign or toxic?
title_fullStr	Are deep eutectic solvents benign or toxic?
title_full_unstemmed	Are deep eutectic solvents benign or toxic?
title_sort	are deep eutectic solvents benign or toxic?
publisher	Elsevier Inc.
publishDate	2013
url	http://irep.iium.edu.my/29509/ http://irep.iium.edu.my/29509/ http://irep.iium.edu.my/29509/ http://irep.iium.edu.my/29509/1/CHEM13334.pdf
first_indexed	2023-09-18T20:43:19Z
last_indexed	2023-09-18T20:43:19Z
_version_	1777409510271352832

Are deep eutectic solvents benign or toxic?

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