Antimicrobial activity of Acalypha indica Linn. extract
The objective for this research undertaken was to evaluate Acalypha indica extracts for their antimicrobial potential. Fresh plant samples were extracted via maceration in increasing polarity using petroleum ether, chloroform and methanol. Antimicrobial activity of the extracts was assessed usi...
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| Language: | English English English |
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2013
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| Online Access: | http://irep.iium.edu.my/29440/ http://irep.iium.edu.my/29440/1/P-138_Farah_Dayana_Ishak.pdf http://irep.iium.edu.my/29440/3/PosterAntimicrob%28rev%29.pdf http://irep.iium.edu.my/29440/2/ANTIMICROBIAL_ACTIVITY_OF_ACALYPHA_INDICA_%281%29.pdf |
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iium-294402013-09-20T03:53:09Z http://irep.iium.edu.my/29440/ Antimicrobial activity of Acalypha indica Linn. extract Ishak, Farah Dayana Mat So'ad, Siti Zaiton Asmali Jauhari, Anis Hazirah Mashud, Nini Nadira Mohd Hassan, Norazian QD Chemistry The objective for this research undertaken was to evaluate Acalypha indica extracts for their antimicrobial potential. Fresh plant samples were extracted via maceration in increasing polarity using petroleum ether, chloroform and methanol. Antimicrobial activity of the extracts was assessed using disc diffusion assay and minimum inhibitory concentration. It was observed that the crude methanol leaves, stembark and chloroform stembark extracts exhibit antimicrobial activity towards both Staphylococcus aureus bacteria and Candida albicans fungi. The inhibition zones recorded in milimeters by the chloroform stembark extracts were 9.57±0.51 (200 mg/mL), 8.33±0.58 (100 mg/mL) and 7.33±0.58 (50 mg/mL) while methanol stembark extract recorded inhibition zones at 13.67±0.58 (200 mg/mL), 10.00±1.00 (100 mg/mL) and 9.33±0.58 (50 mg/mL) against S. aureus. Antifungal activity was also detected against C. albicans as the chloroform stembark extract produced inhibition zones of 14.33±0.58 (200 mg/mL), 13.33±0.58 (100 mg/mL) and 12.67±0.58 (50 mg/mL) while the methanol stembark extract resulted in inhibition zones of 15.33±0.58 (200 mg/mL), 14.33±0.58 (100 mg/mL) and 13.0±0.00 (50 mg/mL). In the case of crude methanol leaves extract, the extract produced inhibition zones of 19±0.58 (200 mg/mL), 13±1.00 (100 mg/mL) and 10±1.00 (50 mg/mL) against S. aureus while against C. albicans, the extract recorded inhibition zones of 15±0.58 (200 mg/mL), 14±0.00 (100 mg/mL) and 13±0.00 (50 mg/mL). The chloroform stembark crude extract developed a medium MIC value of 0.938 mg/mL while both methanol crude extracts produced a strong MIC value of 0.469 mg/mL during the minimum inhibition concentration screening against Candida albicans. 2013 Conference or Workshop Item PeerReviewed application/pdf en http://irep.iium.edu.my/29440/1/P-138_Farah_Dayana_Ishak.pdf application/pdf en http://irep.iium.edu.my/29440/3/PosterAntimicrob%28rev%29.pdf application/pdf en http://irep.iium.edu.my/29440/2/ANTIMICROBIAL_ACTIVITY_OF_ACALYPHA_INDICA_%281%29.pdf Ishak, Farah Dayana and Mat So'ad, Siti Zaiton and Asmali Jauhari, Anis Hazirah and Mashud, Nini Nadira and Mohd Hassan, Norazian (2013) Antimicrobial activity of Acalypha indica Linn. extract. In: International Conference on Natural Products 2013, 4-6 March 2013, Shah Alam Convention Centre, Selangor. (In Press) |
| repository_type |
Digital Repository |
| institution_category |
Local University |
| institution |
International Islamic University Malaysia |
| building |
IIUM Repository |
| collection |
Online Access |
| language |
English English English |
| topic |
QD Chemistry |
| spellingShingle |
QD Chemistry Ishak, Farah Dayana Mat So'ad, Siti Zaiton Asmali Jauhari, Anis Hazirah Mashud, Nini Nadira Mohd Hassan, Norazian Antimicrobial activity of Acalypha indica Linn. extract |
| description |
The objective for this research undertaken was to evaluate Acalypha indica extracts for their
antimicrobial potential. Fresh plant samples were extracted via maceration in increasing
polarity using petroleum ether, chloroform and methanol. Antimicrobial activity of the
extracts was assessed using disc diffusion assay and minimum inhibitory concentration. It
was observed that the crude methanol leaves, stembark and chloroform stembark extracts
exhibit antimicrobial activity towards both Staphylococcus aureus bacteria and Candida
albicans fungi. The inhibition zones recorded in milimeters by the chloroform stembark
extracts were 9.57±0.51 (200 mg/mL), 8.33±0.58 (100 mg/mL) and 7.33±0.58 (50 mg/mL)
while methanol stembark extract recorded inhibition zones at 13.67±0.58 (200 mg/mL),
10.00±1.00 (100 mg/mL) and 9.33±0.58 (50 mg/mL) against S. aureus. Antifungal activity
was also detected against C. albicans as the chloroform stembark extract produced inhibition
zones of 14.33±0.58 (200 mg/mL), 13.33±0.58 (100 mg/mL) and 12.67±0.58 (50 mg/mL)
while the methanol stembark extract resulted in inhibition zones of 15.33±0.58 (200 mg/mL),
14.33±0.58 (100 mg/mL) and 13.0±0.00 (50 mg/mL). In the case of crude methanol leaves
extract, the extract produced inhibition zones of 19±0.58 (200 mg/mL), 13±1.00 (100
mg/mL) and 10±1.00 (50 mg/mL) against S. aureus while against C. albicans, the extract
recorded inhibition zones of 15±0.58 (200 mg/mL), 14±0.00 (100 mg/mL) and 13±0.00 (50
mg/mL). The chloroform stembark crude extract developed a medium MIC value of 0.938
mg/mL while both methanol crude extracts produced a strong MIC value of 0.469 mg/mL
during the minimum inhibition concentration screening against Candida albicans. |
| format |
Conference or Workshop Item |
| author |
Ishak, Farah Dayana Mat So'ad, Siti Zaiton Asmali Jauhari, Anis Hazirah Mashud, Nini Nadira Mohd Hassan, Norazian |
| author_facet |
Ishak, Farah Dayana Mat So'ad, Siti Zaiton Asmali Jauhari, Anis Hazirah Mashud, Nini Nadira Mohd Hassan, Norazian |
| author_sort |
Ishak, Farah Dayana |
| title |
Antimicrobial activity of Acalypha indica Linn. extract |
| title_short |
Antimicrobial activity of Acalypha indica Linn. extract |
| title_full |
Antimicrobial activity of Acalypha indica Linn. extract |
| title_fullStr |
Antimicrobial activity of Acalypha indica Linn. extract |
| title_full_unstemmed |
Antimicrobial activity of Acalypha indica Linn. extract |
| title_sort |
antimicrobial activity of acalypha indica linn. extract |
| publishDate |
2013 |
| url |
http://irep.iium.edu.my/29440/ http://irep.iium.edu.my/29440/1/P-138_Farah_Dayana_Ishak.pdf http://irep.iium.edu.my/29440/3/PosterAntimicrob%28rev%29.pdf http://irep.iium.edu.my/29440/2/ANTIMICROBIAL_ACTIVITY_OF_ACALYPHA_INDICA_%281%29.pdf |
| first_indexed |
2023-09-18T20:43:13Z |
| last_indexed |
2023-09-18T20:43:13Z |
| _version_ |
1777409503510134784 |