β-Cyclodextrin conjugated magnetic, fluorescent silica core-shell nanoparticles for biomedical applications
We present synthesis of highly uniform magnetic nanocomposite material possessing an assortment of important functionalities: magnetism, luminescence, cell-targeting, and hydrophobic drug delivery. Magnetic particle Fe 3O4 is encapsulated within a shell of SiO2 that ensures biocompatibility of the n...
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2013
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iium-293072014-02-14T03:05:31Z http://irep.iium.edu.my/29307/ β-Cyclodextrin conjugated magnetic, fluorescent silica core-shell nanoparticles for biomedical applications Md. Badruddoza , Abu Zayed Rahman , Md. Taifur Ghosh , Sudipa Hossain , Md. Zakir Shi , Jizhong Hidajat , Kus Uddin, Mohammad Shahab TP155 Chemical engineering TP248.13 Biotechnology We present synthesis of highly uniform magnetic nanocomposite material possessing an assortment of important functionalities: magnetism, luminescence, cell-targeting, and hydrophobic drug delivery. Magnetic particle Fe 3O4 is encapsulated within a shell of SiO2 that ensures biocompatibility of the nanocomposite as well as act as a host for fluorescent dye (FITC), cancer-targeting ligand (folic acid), and a hydrophobic drug storage-delivering vehicle (β-cyclodextrin). Our preliminary results suggest that such core-shell nanocomposite can be a smart theranostic candidate for simultaneous fluorescence imaging, magnetic manipulation, cancer cell-targeting and hydrophobic drug delivery. Elsevier Ltd. 2013-06-05 Article PeerReviewed application/pdf en http://irep.iium.edu.my/29307/1/shahab__%CE%B2-Cyclodextrin_1-s2.0-S0144861713001859-main.pdf Md. Badruddoza , Abu Zayed and Rahman , Md. Taifur and Ghosh , Sudipa and Hossain , Md. Zakir and Shi , Jizhong and Hidajat , Kus and Uddin, Mohammad Shahab (2013) β-Cyclodextrin conjugated magnetic, fluorescent silica core-shell nanoparticles for biomedical applications. Carbohydrate Polymers, 95 (1). pp. 449-457. ISSN 0144-8617 (O) 10.1016/j.carbpol.2013.02.046 |
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TP155 Chemical engineering TP248.13 Biotechnology |
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TP155 Chemical engineering TP248.13 Biotechnology Md. Badruddoza , Abu Zayed Rahman , Md. Taifur Ghosh , Sudipa Hossain , Md. Zakir Shi , Jizhong Hidajat , Kus Uddin, Mohammad Shahab β-Cyclodextrin conjugated magnetic, fluorescent silica core-shell nanoparticles for biomedical applications |
description |
We present synthesis of highly uniform magnetic nanocomposite material possessing an assortment of important functionalities: magnetism, luminescence, cell-targeting, and hydrophobic drug delivery. Magnetic particle Fe 3O4 is encapsulated within a shell of SiO2 that ensures biocompatibility of the nanocomposite as well as act as a host for fluorescent dye (FITC), cancer-targeting ligand (folic acid), and a hydrophobic drug storage-delivering vehicle (β-cyclodextrin). Our preliminary results suggest that such core-shell nanocomposite can be a smart theranostic candidate for simultaneous fluorescence imaging, magnetic manipulation, cancer cell-targeting and hydrophobic drug delivery. |
format |
Article |
author |
Md. Badruddoza , Abu Zayed Rahman , Md. Taifur Ghosh , Sudipa Hossain , Md. Zakir Shi , Jizhong Hidajat , Kus Uddin, Mohammad Shahab |
author_facet |
Md. Badruddoza , Abu Zayed Rahman , Md. Taifur Ghosh , Sudipa Hossain , Md. Zakir Shi , Jizhong Hidajat , Kus Uddin, Mohammad Shahab |
author_sort |
Md. Badruddoza , Abu Zayed |
title |
β-Cyclodextrin conjugated magnetic, fluorescent silica core-shell nanoparticles for biomedical applications
|
title_short |
β-Cyclodextrin conjugated magnetic, fluorescent silica core-shell nanoparticles for biomedical applications
|
title_full |
β-Cyclodextrin conjugated magnetic, fluorescent silica core-shell nanoparticles for biomedical applications
|
title_fullStr |
β-Cyclodextrin conjugated magnetic, fluorescent silica core-shell nanoparticles for biomedical applications
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title_full_unstemmed |
β-Cyclodextrin conjugated magnetic, fluorescent silica core-shell nanoparticles for biomedical applications
|
title_sort |
β-cyclodextrin conjugated magnetic, fluorescent silica core-shell nanoparticles for biomedical applications |
publisher |
Elsevier Ltd. |
publishDate |
2013 |
url |
http://irep.iium.edu.my/29307/ http://irep.iium.edu.my/29307/ http://irep.iium.edu.my/29307/1/shahab__%CE%B2-Cyclodextrin_1-s2.0-S0144861713001859-main.pdf |
first_indexed |
2023-09-18T20:43:00Z |
last_indexed |
2023-09-18T20:43:00Z |
_version_ |
1777409490593775616 |