β-Cyclodextrin conjugated magnetic, fluorescent silica core-shell nanoparticles for biomedical applications

We present synthesis of highly uniform magnetic nanocomposite material possessing an assortment of important functionalities: magnetism, luminescence, cell-targeting, and hydrophobic drug delivery. Magnetic particle Fe 3O4 is encapsulated within a shell of SiO2 that ensures biocompatibility of the n...

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Main Authors: Md. Badruddoza , Abu Zayed, Rahman , Md. Taifur, Ghosh , Sudipa, Hossain , Md. Zakir, Shi , Jizhong, Hidajat , Kus, Uddin, Mohammad Shahab
Format: Article
Language:English
Published: Elsevier Ltd. 2013
Subjects:
Online Access:http://irep.iium.edu.my/29307/
http://irep.iium.edu.my/29307/
http://irep.iium.edu.my/29307/1/shahab__%CE%B2-Cyclodextrin_1-s2.0-S0144861713001859-main.pdf
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recordtype eprints
spelling iium-293072014-02-14T03:05:31Z http://irep.iium.edu.my/29307/ β-Cyclodextrin conjugated magnetic, fluorescent silica core-shell nanoparticles for biomedical applications Md. Badruddoza , Abu Zayed Rahman , Md. Taifur Ghosh , Sudipa Hossain , Md. Zakir Shi , Jizhong Hidajat , Kus Uddin, Mohammad Shahab TP155 Chemical engineering TP248.13 Biotechnology We present synthesis of highly uniform magnetic nanocomposite material possessing an assortment of important functionalities: magnetism, luminescence, cell-targeting, and hydrophobic drug delivery. Magnetic particle Fe 3O4 is encapsulated within a shell of SiO2 that ensures biocompatibility of the nanocomposite as well as act as a host for fluorescent dye (FITC), cancer-targeting ligand (folic acid), and a hydrophobic drug storage-delivering vehicle (β-cyclodextrin). Our preliminary results suggest that such core-shell nanocomposite can be a smart theranostic candidate for simultaneous fluorescence imaging, magnetic manipulation, cancer cell-targeting and hydrophobic drug delivery. Elsevier Ltd. 2013-06-05 Article PeerReviewed application/pdf en http://irep.iium.edu.my/29307/1/shahab__%CE%B2-Cyclodextrin_1-s2.0-S0144861713001859-main.pdf Md. Badruddoza , Abu Zayed and Rahman , Md. Taifur and Ghosh , Sudipa and Hossain , Md. Zakir and Shi , Jizhong and Hidajat , Kus and Uddin, Mohammad Shahab (2013) β-Cyclodextrin conjugated magnetic, fluorescent silica core-shell nanoparticles for biomedical applications. Carbohydrate Polymers, 95 (1). pp. 449-457. ISSN 0144-8617 (O) 10.1016/j.carbpol.2013.02.046
repository_type Digital Repository
institution_category Local University
institution International Islamic University Malaysia
building IIUM Repository
collection Online Access
language English
topic TP155 Chemical engineering
TP248.13 Biotechnology
spellingShingle TP155 Chemical engineering
TP248.13 Biotechnology
Md. Badruddoza , Abu Zayed
Rahman , Md. Taifur
Ghosh , Sudipa
Hossain , Md. Zakir
Shi , Jizhong
Hidajat , Kus
Uddin, Mohammad Shahab
β-Cyclodextrin conjugated magnetic, fluorescent silica core-shell nanoparticles for biomedical applications
description We present synthesis of highly uniform magnetic nanocomposite material possessing an assortment of important functionalities: magnetism, luminescence, cell-targeting, and hydrophobic drug delivery. Magnetic particle Fe 3O4 is encapsulated within a shell of SiO2 that ensures biocompatibility of the nanocomposite as well as act as a host for fluorescent dye (FITC), cancer-targeting ligand (folic acid), and a hydrophobic drug storage-delivering vehicle (β-cyclodextrin). Our preliminary results suggest that such core-shell nanocomposite can be a smart theranostic candidate for simultaneous fluorescence imaging, magnetic manipulation, cancer cell-targeting and hydrophobic drug delivery.
format Article
author Md. Badruddoza , Abu Zayed
Rahman , Md. Taifur
Ghosh , Sudipa
Hossain , Md. Zakir
Shi , Jizhong
Hidajat , Kus
Uddin, Mohammad Shahab
author_facet Md. Badruddoza , Abu Zayed
Rahman , Md. Taifur
Ghosh , Sudipa
Hossain , Md. Zakir
Shi , Jizhong
Hidajat , Kus
Uddin, Mohammad Shahab
author_sort Md. Badruddoza , Abu Zayed
title β-Cyclodextrin conjugated magnetic, fluorescent silica core-shell nanoparticles for biomedical applications
title_short β-Cyclodextrin conjugated magnetic, fluorescent silica core-shell nanoparticles for biomedical applications
title_full β-Cyclodextrin conjugated magnetic, fluorescent silica core-shell nanoparticles for biomedical applications
title_fullStr β-Cyclodextrin conjugated magnetic, fluorescent silica core-shell nanoparticles for biomedical applications
title_full_unstemmed β-Cyclodextrin conjugated magnetic, fluorescent silica core-shell nanoparticles for biomedical applications
title_sort β-cyclodextrin conjugated magnetic, fluorescent silica core-shell nanoparticles for biomedical applications
publisher Elsevier Ltd.
publishDate 2013
url http://irep.iium.edu.my/29307/
http://irep.iium.edu.my/29307/
http://irep.iium.edu.my/29307/1/shahab__%CE%B2-Cyclodextrin_1-s2.0-S0144861713001859-main.pdf
first_indexed 2023-09-18T20:43:00Z
last_indexed 2023-09-18T20:43:00Z
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