The influence of premenopausal hystrectomy on bone mineral density

Objective: To investigate whether premenopausal hysterectomy has an effect on bone mass in women in their fifties . Methods: This cross-sectional study was performed on 25 healthy women who had premenopausal hysterectomy before the age of 45 and at least 2 years before the study with 40 healthy...

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Main Authors:	Abdulwahab, Dalia F, Reyad, B, Chabek, M, Awang, Mokhtar, Abd. Wahab, Noraziana, Muna, Q
Format:	Article
Language:	English
Published:	Elsevier Ireland Ltd. 2012
Subjects:	R Medicine (General)
Online Access:	http://irep.iium.edu.my/29266/ http://irep.iium.edu.my/29266/ http://irep.iium.edu.my/29266/ http://irep.iium.edu.my/29266/1/The_influence_of_premenopausal.pdf

id	iium-29266
recordtype	eprints
spelling	iium-292662014-07-16T05:57:49Z http://irep.iium.edu.my/29266/ The influence of premenopausal hystrectomy on bone mineral density Abdulwahab, Dalia F Reyad, B Chabek, M Awang, Mokhtar Abd. Wahab, Noraziana Muna, Q R Medicine (General) Objective: To investigate whether premenopausal hysterectomy has an effect on bone mass in women in their fifties . Methods: This cross-sectional study was performed on 25 healthy women who had premenopausal hysterectomy before the age of 45 and at least 2 years before the study with 40 healthy natural postmenopausal women 45–60 years old. Evaluation of the menopausal state was done by measuring serum follicular stimulating hormone and serum estradiol. Bone mineral density of the left proximal femur was determined by dual energy X-ray absorptiometry in six regions (femoral neck, greater trochanter, interochantric, ward‘s triangle, shaft, total hip region). Evaluation of bone remodeling done by measuring serum alkaline phosphotase. The result of both groups were compared. Results: The study showed slight increment of BMD among cases with hysterectomy than the control group by an amount ranging between 1.9% in the femoral shaft to 4.8% in the greater trochanter and ward‘s triangle. These differences were not statistically significant and even when they were exceptionally significant as the case with BMD of the femoral neck and intertrochantric area they were too small in magnitude to be of clinical relevance. Conclusion: Hysterectomy had no impact on bone parameters even after adjusting for the duration of menopause. Elsevier Ireland Ltd. 2012-06-04 Article PeerReviewed application/pdf en http://irep.iium.edu.my/29266/1/The_influence_of_premenopausal.pdf Abdulwahab, Dalia F and Reyad, B and Chabek, M and Awang, Mokhtar and Abd. Wahab, Noraziana and Muna, Q (2012) The influence of premenopausal hystrectomy on bone mineral density. BJOG: An International Journal of Obstetrics & Gynaecology, 119 (Oct.). p. 225. ISSN ISSN: 1471-0528 (O), 1470-0328 (P) http://onlinelibrary.wiley.com/doi/10.1111/j.1471-0528.2012.03382.x/pdf 10.1111/j.1471-0528.2012.03382.x
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English
topic	R Medicine (General)
spellingShingle	R Medicine (General) Abdulwahab, Dalia F Reyad, B Chabek, M Awang, Mokhtar Abd. Wahab, Noraziana Muna, Q The influence of premenopausal hystrectomy on bone mineral density
description	Objective: To investigate whether premenopausal hysterectomy has an effect on bone mass in women in their fifties . Methods: This cross-sectional study was performed on 25 healthy women who had premenopausal hysterectomy before the age of 45 and at least 2 years before the study with 40 healthy natural postmenopausal women 45–60 years old. Evaluation of the menopausal state was done by measuring serum follicular stimulating hormone and serum estradiol. Bone mineral density of the left proximal femur was determined by dual energy X-ray absorptiometry in six regions (femoral neck, greater trochanter, interochantric, ward‘s triangle, shaft, total hip region). Evaluation of bone remodeling done by measuring serum alkaline phosphotase. The result of both groups were compared. Results: The study showed slight increment of BMD among cases with hysterectomy than the control group by an amount ranging between 1.9% in the femoral shaft to 4.8% in the greater trochanter and ward‘s triangle. These differences were not statistically significant and even when they were exceptionally significant as the case with BMD of the femoral neck and intertrochantric area they were too small in magnitude to be of clinical relevance. Conclusion: Hysterectomy had no impact on bone parameters even after adjusting for the duration of menopause.
format	Article
author	Abdulwahab, Dalia F Reyad, B Chabek, M Awang, Mokhtar Abd. Wahab, Noraziana Muna, Q
author_facet	Abdulwahab, Dalia F Reyad, B Chabek, M Awang, Mokhtar Abd. Wahab, Noraziana Muna, Q
author_sort	Abdulwahab, Dalia F
title	The influence of premenopausal hystrectomy on bone mineral density
title_short	The influence of premenopausal hystrectomy on bone mineral density
title_full	The influence of premenopausal hystrectomy on bone mineral density
title_fullStr	The influence of premenopausal hystrectomy on bone mineral density
title_full_unstemmed	The influence of premenopausal hystrectomy on bone mineral density
title_sort	influence of premenopausal hystrectomy on bone mineral density
publisher	Elsevier Ireland Ltd.
publishDate	2012
url	http://irep.iium.edu.my/29266/ http://irep.iium.edu.my/29266/ http://irep.iium.edu.my/29266/ http://irep.iium.edu.my/29266/1/The_influence_of_premenopausal.pdf
first_indexed	2023-09-18T20:42:56Z
last_indexed	2023-09-18T20:42:56Z
_version_	1777409486361722880

The influence of premenopausal hystrectomy on bone mineral density

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