Transitional changes in the mucosa adjacent to the colorectal carcinoma- A SEM study

Colorectal cancer is the fourth most common cancer worldwide, with about 677,000 deaths each year. The term transitional mucosa™ was coined by Filipe in 1969 to describe alterations in the morphology and mucin histochemistry of the large intestinal mucosa immediately adjacent to colorectal adenocarc...

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Main Authors:	Ansari, Reshma.M., Tun, Ye, Md Nor, Azmi, Myint, Yi Yi
Format:	Article
Language:	English
Published:	Universiti Putra Malaysia 2012
Subjects:	R Medicine (General)
Online Access:	http://irep.iium.edu.my/27233/ http://irep.iium.edu.my/27233/1/Transitional_Mucosa.pdf

id	iium-27233
recordtype	eprints
spelling	iium-272332014-05-30T08:54:43Z http://irep.iium.edu.my/27233/ Transitional changes in the mucosa adjacent to the colorectal carcinoma- A SEM study Ansari, Reshma.M. Tun, Ye Md Nor, Azmi Myint, Yi Yi R Medicine (General) Colorectal cancer is the fourth most common cancer worldwide, with about 677,000 deaths each year. The term transitional mucosa™ was coined by Filipe in 1969 to describe alterations in the morphology and mucin histochemistry of the large intestinal mucosa immediately adjacent to colorectal adenocarcinomas. The TM is considered as an important prognostic marker for patients with large bowel cancer following radical resection because patients with retained TM have a poorer prognosis. 3 samples from the proximal margin of a resected colorectal surgical specimen were taken to study the extent of the transitional changes in them. They were selected approximately 2cms, 5cms and 10cms away from the tumor site. The tissues were then processed and viewed under Scanning Electron microscope (SEM) to gauge the extent of the transitional changes. These changes were compared with the normal colon samples taken from normal patients. Transitional changes were found both near as well as farther away from the tumor and were characterized. Universiti Putra Malaysia 2012-11 Article PeerReviewed application/pdf en http://irep.iium.edu.my/27233/1/Transitional_Mucosa.pdf Ansari, Reshma.M. and Tun, Ye and Md Nor, Azmi and Myint, Yi Yi (2012) Transitional changes in the mucosa adjacent to the colorectal carcinoma- A SEM study. Malaysian Journal of Microscopy, 8. pp. 127-132. ISSN 1823-7010
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English
topic	R Medicine (General)
spellingShingle	R Medicine (General) Ansari, Reshma.M. Tun, Ye Md Nor, Azmi Myint, Yi Yi Transitional changes in the mucosa adjacent to the colorectal carcinoma- A SEM study
description	Colorectal cancer is the fourth most common cancer worldwide, with about 677,000 deaths each year. The term transitional mucosa™ was coined by Filipe in 1969 to describe alterations in the morphology and mucin histochemistry of the large intestinal mucosa immediately adjacent to colorectal adenocarcinomas. The TM is considered as an important prognostic marker for patients with large bowel cancer following radical resection because patients with retained TM have a poorer prognosis. 3 samples from the proximal margin of a resected colorectal surgical specimen were taken to study the extent of the transitional changes in them. They were selected approximately 2cms, 5cms and 10cms away from the tumor site. The tissues were then processed and viewed under Scanning Electron microscope (SEM) to gauge the extent of the transitional changes. These changes were compared with the normal colon samples taken from normal patients. Transitional changes were found both near as well as farther away from the tumor and were characterized.
format	Article
author	Ansari, Reshma.M. Tun, Ye Md Nor, Azmi Myint, Yi Yi
author_facet	Ansari, Reshma.M. Tun, Ye Md Nor, Azmi Myint, Yi Yi
author_sort	Ansari, Reshma.M.
title	Transitional changes in the mucosa adjacent to the colorectal carcinoma- A SEM study
title_short	Transitional changes in the mucosa adjacent to the colorectal carcinoma- A SEM study
title_full	Transitional changes in the mucosa adjacent to the colorectal carcinoma- A SEM study
title_fullStr	Transitional changes in the mucosa adjacent to the colorectal carcinoma- A SEM study
title_full_unstemmed	Transitional changes in the mucosa adjacent to the colorectal carcinoma- A SEM study
title_sort	transitional changes in the mucosa adjacent to the colorectal carcinoma- a sem study
publisher	Universiti Putra Malaysia
publishDate	2012
url	http://irep.iium.edu.my/27233/ http://irep.iium.edu.my/27233/1/Transitional_Mucosa.pdf
first_indexed	2023-09-18T20:40:31Z
last_indexed	2023-09-18T20:40:31Z
_version_	1777409333584199680

Transitional changes in the mucosa adjacent to the colorectal carcinoma- A SEM study

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