Galactgogue effects on Musa x paradisiaca flower extract on the lactating rats
Objective To investigate the potential of Musaxparadisiaca (M. xparadisiaca) flower extracts in promoting milk production of lactating rats and its effects on growth of the suckling pups. Methods Galactagogue activity was evaluated in terms of quantity of milk produced from the rats treated wit...
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Elsevier
2012
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iium-269732014-07-17T04:49:12Z http://irep.iium.edu.my/26973/ Galactgogue effects on Musa x paradisiaca flower extract on the lactating rats Mahmood, Azizah Omar, Muhammad Nor Ngah, Nurziana Q Science (General) Objective To investigate the potential of Musaxparadisiaca (M. xparadisiaca) flower extracts in promoting milk production of lactating rats and its effects on growth of the suckling pups. Methods Galactagogue activity was evaluated in terms of quantity of milk produced from the rats treated with petroleum ether, ethanol or water extracts of the flower. Lactating rats (n = 5) of Spraque Dawley with six pups each were administered with the extracts in the amount of 500 mg/kg body weight, while the control rats were given an equivalent amount of distilled water. The rats were daily administered via oral feeding starting from Day 5 until Day 14 and the performance of milk production was measured along the experimental period by weight-suckle-weight method. Results were statistically analyzed using SPSS by means of ANOVA at 0.05 and was expressed as their mean?standard deviation. The rates of pups' growth were measured as the weight gain along the experimental period. Results The rats treated with aqueous extract produced higher milk than control and ethanol groups. Aqueous extract was identified to increase milk production by 25%, while petroleum ether extract by 18%. The mean of yields produced by the rats during suckling period for aqueous, petroleum ether, ethanol and control were 4.62±2.45, 4.37±1.93, 3.65±1.89 and 3.69±1.79, respectively. Growth rates of pups for the rats treated with control, aqueous, ethanol extract and petroleum ether were (1.85±0.49), (1.78±0.56), (1.65±0.46) and (1.56±0.42) g/pup, respectively. Conclusions The present study reveals the potential of M. xparadisiacaflower to enhance milk production of nursing mothers which could be exploited for commercialization of the isolated extract. Elsevier 2012-11-20 Article PeerReviewed application/pdf en http://irep.iium.edu.my/26973/1/Azizah_Mahmood_et_al._%282012%29.pdf Mahmood, Azizah and Omar, Muhammad Nor and Ngah, Nurziana (2012) Galactgogue effects on Musa x paradisiaca flower extract on the lactating rats. Asian Pacific Journal of Tropical Medicine, 5 (11). pp. 882-886. ISSN 1995-7645 http://www.sciencedirect.com/science/article/pii/S1995764512601643 10.1016/S1995-7645(12)60164-3 |
| repository_type |
Digital Repository |
| institution_category |
Local University |
| institution |
International Islamic University Malaysia |
| building |
IIUM Repository |
| collection |
Online Access |
| language |
English |
| topic |
Q Science (General) |
| spellingShingle |
Q Science (General) Mahmood, Azizah Omar, Muhammad Nor Ngah, Nurziana Galactgogue effects on Musa x paradisiaca flower extract on the lactating rats |
| description |
Objective
To investigate the potential of Musaxparadisiaca (M. xparadisiaca) flower extracts in promoting milk production of lactating rats and its effects on growth of the suckling pups.
Methods
Galactagogue activity was evaluated in terms of quantity of milk produced from the rats treated with petroleum ether, ethanol or water extracts of the flower. Lactating rats (n = 5) of Spraque Dawley with six pups each were administered with the extracts in the amount of 500 mg/kg body weight, while the control rats were given an equivalent amount of distilled water. The rats were daily administered via oral feeding starting from Day 5 until Day 14 and the performance of milk production was measured along the experimental period by weight-suckle-weight method. Results were statistically analyzed using SPSS by means of ANOVA at 0.05 and was expressed as their mean?standard deviation. The rates of pups' growth were measured as the weight gain along the experimental period.
Results
The rats treated with aqueous extract produced higher milk than control and ethanol groups. Aqueous extract was identified to increase milk production by 25%, while petroleum ether extract by 18%. The mean of yields produced by the rats during suckling period for aqueous, petroleum ether, ethanol and control were 4.62±2.45, 4.37±1.93, 3.65±1.89 and 3.69±1.79, respectively. Growth rates of pups for the rats treated with control, aqueous, ethanol extract and petroleum ether were (1.85±0.49), (1.78±0.56), (1.65±0.46) and (1.56±0.42) g/pup, respectively.
Conclusions
The present study reveals the potential of M. xparadisiacaflower to enhance milk production of nursing mothers which could be exploited for commercialization of the isolated extract. |
| format |
Article |
| author |
Mahmood, Azizah Omar, Muhammad Nor Ngah, Nurziana |
| author_facet |
Mahmood, Azizah Omar, Muhammad Nor Ngah, Nurziana |
| author_sort |
Mahmood, Azizah |
| title |
Galactgogue effects on Musa x paradisiaca flower extract on the lactating rats |
| title_short |
Galactgogue effects on Musa x paradisiaca flower extract on the lactating rats |
| title_full |
Galactgogue effects on Musa x paradisiaca flower extract on the lactating rats |
| title_fullStr |
Galactgogue effects on Musa x paradisiaca flower extract on the lactating rats |
| title_full_unstemmed |
Galactgogue effects on Musa x paradisiaca flower extract on the lactating rats |
| title_sort |
galactgogue effects on musa x paradisiaca flower extract on the lactating rats |
| publisher |
Elsevier |
| publishDate |
2012 |
| url |
http://irep.iium.edu.my/26973/ http://irep.iium.edu.my/26973/ http://irep.iium.edu.my/26973/ http://irep.iium.edu.my/26973/1/Azizah_Mahmood_et_al._%282012%29.pdf |
| first_indexed |
2023-09-18T20:40:06Z |
| last_indexed |
2023-09-18T20:40:06Z |
| _version_ |
1777409307977973760 |