Evaluation of antimicrobial activity of Artocarpus altilis on pathogenic microorganisms

The study was aimed to evaluate the antimicrobial, MIC and MBC/MFC activities of Artocarpus altilis (twigs). In vitro antimicrobial activity was evaluated against six pathogenic microorganisms (two gram positive strains: Staphylococcus aureus (ATCC-25923) and Bacillus cereus (ATCC-11778), the Gram n...

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Main Authors:	Kamal, Tara, Muzammil, Ahmad, Omar, Muhammad Nor
Format:	Article
Language:	English
Published:	Academic Information Press 2012
Subjects:	QK Botany
Online Access:	http://irep.iium.edu.my/26213/ http://irep.iium.edu.my/26213/ http://irep.iium.edu.my/26213/1/Tara_Evaluation_of_antimicrobial_Artocarpus_altilis_Science_Series_Data_Report.pdf

id	iium-26213
recordtype	eprints
spelling	iium-262132014-07-16T07:56:09Z http://irep.iium.edu.my/26213/ Evaluation of antimicrobial activity of Artocarpus altilis on pathogenic microorganisms Kamal, Tara Muzammil, Ahmad Omar, Muhammad Nor QK Botany The study was aimed to evaluate the antimicrobial, MIC and MBC/MFC activities of Artocarpus altilis (twigs). In vitro antimicrobial activity was evaluated against six pathogenic microorganisms (two gram positive strains: Staphylococcus aureus (ATCC-25923) and Bacillus cereus (ATCC-11778), the Gram negative strains Escherichia coli (ATCC- 35218) and Pseudomonas aeruginosa (ATCC -27853), and two fungal strains: Candida albicans (ATCC -10231) and Cryptococcus neoformans (ATCC- 90112)) using the disc diffusion method at 2mg/disc by indicating the presence of the clear inhibition zones around each disc compared with the positive control (Streptomycin and Nystatin), while the MIC and MBC/MFC were ranged from (250-1000μg/ml) assayed by using the 96 well plates. The dried twigs of A. altilis were extracted by using the Soxhlet apparatus. The extracts of hexane and DCM were observed a moderate antimicrobial activity at (14.6±0.2mm) against Bacillus cereus, whereas 11.8±0.3mm and 11.5±0.2mm values for C. albicans respectively. The least MIC of 250μg/ml was obtained by DCM extract against S. aureus for bacteria and C. albicans and C. neoformans for fungus respectively. The results suggested that Artocarpus altilis extracts have promising therapeutic potential against bacteria and fungi. Academic Information Press 2012-09 Article PeerReviewed application/pdf en http://irep.iium.edu.my/26213/1/Tara_Evaluation_of_antimicrobial_Artocarpus_altilis_Science_Series_Data_Report.pdf Kamal, Tara and Muzammil, Ahmad and Omar, Muhammad Nor (2012) Evaluation of antimicrobial activity of Artocarpus altilis on pathogenic microorganisms. Science Series Data Report, 4 (9). pp. 41-48. ISSN 1307-119X http://www.ssdr.sciencerecord.com/auto/index.php/archive/part/4/9/2/?currentVol=4&currentissue=9
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English
topic	QK Botany
spellingShingle	QK Botany Kamal, Tara Muzammil, Ahmad Omar, Muhammad Nor Evaluation of antimicrobial activity of Artocarpus altilis on pathogenic microorganisms
description	The study was aimed to evaluate the antimicrobial, MIC and MBC/MFC activities of Artocarpus altilis (twigs). In vitro antimicrobial activity was evaluated against six pathogenic microorganisms (two gram positive strains: Staphylococcus aureus (ATCC-25923) and Bacillus cereus (ATCC-11778), the Gram negative strains Escherichia coli (ATCC- 35218) and Pseudomonas aeruginosa (ATCC -27853), and two fungal strains: Candida albicans (ATCC -10231) and Cryptococcus neoformans (ATCC- 90112)) using the disc diffusion method at 2mg/disc by indicating the presence of the clear inhibition zones around each disc compared with the positive control (Streptomycin and Nystatin), while the MIC and MBC/MFC were ranged from (250-1000μg/ml) assayed by using the 96 well plates. The dried twigs of A. altilis were extracted by using the Soxhlet apparatus. The extracts of hexane and DCM were observed a moderate antimicrobial activity at (14.6±0.2mm) against Bacillus cereus, whereas 11.8±0.3mm and 11.5±0.2mm values for C. albicans respectively. The least MIC of 250μg/ml was obtained by DCM extract against S. aureus for bacteria and C. albicans and C. neoformans for fungus respectively. The results suggested that Artocarpus altilis extracts have promising therapeutic potential against bacteria and fungi.
format	Article
author	Kamal, Tara Muzammil, Ahmad Omar, Muhammad Nor
author_facet	Kamal, Tara Muzammil, Ahmad Omar, Muhammad Nor
author_sort	Kamal, Tara
title	Evaluation of antimicrobial activity of Artocarpus altilis on pathogenic microorganisms
title_short	Evaluation of antimicrobial activity of Artocarpus altilis on pathogenic microorganisms
title_full	Evaluation of antimicrobial activity of Artocarpus altilis on pathogenic microorganisms
title_fullStr	Evaluation of antimicrobial activity of Artocarpus altilis on pathogenic microorganisms
title_full_unstemmed	Evaluation of antimicrobial activity of Artocarpus altilis on pathogenic microorganisms
title_sort	evaluation of antimicrobial activity of artocarpus altilis on pathogenic microorganisms
publisher	Academic Information Press
publishDate	2012
url	http://irep.iium.edu.my/26213/ http://irep.iium.edu.my/26213/ http://irep.iium.edu.my/26213/1/Tara_Evaluation_of_antimicrobial_Artocarpus_altilis_Science_Series_Data_Report.pdf
first_indexed	2023-09-18T20:39:03Z
last_indexed	2023-09-18T20:39:03Z
_version_	1777409241896714240

Evaluation of antimicrobial activity of Artocarpus altilis on pathogenic microorganisms

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