The association between sleep apnea and young adult with hypertension: a case-control study in Malaysia

Objectives: To study the association between sleep apnea and hypertension in a younger age group than previously studied. Methods: We analyzed data on sleep-disordered breathing (based on polysomnography tests), body mass index (BMI), neck circumference, upper airway endoscopy sizes, and habitus an...

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Main Authors: Asha'ari, Zamzil Amin, Hasmoni, Mohamed Hadzri, Ab Rahman, Jamalludin, Yusof, Rosnida Azura, Raja Lope Ahmad, Raja Ahmad Al'konee
Format: Conference or Workshop Item
Language:English
Published: 2012
Subjects:
Online Access:http://irep.iium.edu.my/26076/
http://irep.iium.edu.my/26076/
http://irep.iium.edu.my/26076/1/association_between_sleep_apnea.pdf
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recordtype eprints
spelling iium-260762016-03-10T06:57:06Z http://irep.iium.edu.my/26076/ The association between sleep apnea and young adult with hypertension: a case-control study in Malaysia Asha'ari, Zamzil Amin Hasmoni, Mohamed Hadzri Ab Rahman, Jamalludin Yusof, Rosnida Azura Raja Lope Ahmad, Raja Ahmad Al'konee RF Otorhinolaryngology Objectives: To study the association between sleep apnea and hypertension in a younger age group than previously studied. Methods: We analyzed data on sleep-disordered breathing (based on polysomnography tests), body mass index (BMI), neck circumference, upper airway endoscopy sizes, and habitus and health history in 120 hypertensive and 120 nonhypertensive participants in a clinic-based setting. Independent t test, chi-square, multivariate analysis, and binary logistic regression models were used for case-control comparison. Age group of the participants were 18-40 years. Results: Persons with hypertension had an OR of 2.7 times of having comorbid sleep apnea than patients without hypertension (95% confidence interval [CI] 1.2-6.1). Persons with sleep apnea (AHI [apnea-hypopnea index] 5) had an OR of 2.76 (95% CI 1.57-4.86), and persons with severe sleep apnea (AHI 30) had an OR 7.94 (95% CI 4.21-15.33) for having hypertension than did persons without sleep apnea. Although adjustments for the compounding factors, particularly BMI, decreased the OR to a large degree, subjects with severe sleep apnea were still 72% more likely to have hypertension than subjects without sleep apnea (Table 1). Conclusions: Sleep apnea is related to hypertension in the young adults. The association was more pronounced with the increasing severity of sleep apnea. Screening for sleep apnea should be considered in young adults with hypertension. 2012-08 Conference or Workshop Item PeerReviewed application/pdf en http://irep.iium.edu.my/26076/1/association_between_sleep_apnea.pdf Asha'ari, Zamzil Amin and Hasmoni, Mohamed Hadzri and Ab Rahman, Jamalludin and Yusof, Rosnida Azura and Raja Lope Ahmad, Raja Ahmad Al'konee (2012) The association between sleep apnea and young adult with hypertension: a case-control study in Malaysia. In: X World Congress on Sleep Apnea (ROMA 2012), 27 August- 1 September 2012, Rome, Italy. http://www.wcsa2012.com/
repository_type Digital Repository
institution_category Local University
institution International Islamic University Malaysia
building IIUM Repository
collection Online Access
language English
topic RF Otorhinolaryngology
spellingShingle RF Otorhinolaryngology
Asha'ari, Zamzil Amin
Hasmoni, Mohamed Hadzri
Ab Rahman, Jamalludin
Yusof, Rosnida Azura
Raja Lope Ahmad, Raja Ahmad Al'konee
The association between sleep apnea and young adult with hypertension: a case-control study in Malaysia
description Objectives: To study the association between sleep apnea and hypertension in a younger age group than previously studied. Methods: We analyzed data on sleep-disordered breathing (based on polysomnography tests), body mass index (BMI), neck circumference, upper airway endoscopy sizes, and habitus and health history in 120 hypertensive and 120 nonhypertensive participants in a clinic-based setting. Independent t test, chi-square, multivariate analysis, and binary logistic regression models were used for case-control comparison. Age group of the participants were 18-40 years. Results: Persons with hypertension had an OR of 2.7 times of having comorbid sleep apnea than patients without hypertension (95% confidence interval [CI] 1.2-6.1). Persons with sleep apnea (AHI [apnea-hypopnea index] 5) had an OR of 2.76 (95% CI 1.57-4.86), and persons with severe sleep apnea (AHI 30) had an OR 7.94 (95% CI 4.21-15.33) for having hypertension than did persons without sleep apnea. Although adjustments for the compounding factors, particularly BMI, decreased the OR to a large degree, subjects with severe sleep apnea were still 72% more likely to have hypertension than subjects without sleep apnea (Table 1). Conclusions: Sleep apnea is related to hypertension in the young adults. The association was more pronounced with the increasing severity of sleep apnea. Screening for sleep apnea should be considered in young adults with hypertension.
format Conference or Workshop Item
author Asha'ari, Zamzil Amin
Hasmoni, Mohamed Hadzri
Ab Rahman, Jamalludin
Yusof, Rosnida Azura
Raja Lope Ahmad, Raja Ahmad Al'konee
author_facet Asha'ari, Zamzil Amin
Hasmoni, Mohamed Hadzri
Ab Rahman, Jamalludin
Yusof, Rosnida Azura
Raja Lope Ahmad, Raja Ahmad Al'konee
author_sort Asha'ari, Zamzil Amin
title The association between sleep apnea and young adult with hypertension: a case-control study in Malaysia
title_short The association between sleep apnea and young adult with hypertension: a case-control study in Malaysia
title_full The association between sleep apnea and young adult with hypertension: a case-control study in Malaysia
title_fullStr The association between sleep apnea and young adult with hypertension: a case-control study in Malaysia
title_full_unstemmed The association between sleep apnea and young adult with hypertension: a case-control study in Malaysia
title_sort association between sleep apnea and young adult with hypertension: a case-control study in malaysia
publishDate 2012
url http://irep.iium.edu.my/26076/
http://irep.iium.edu.my/26076/
http://irep.iium.edu.my/26076/1/association_between_sleep_apnea.pdf
first_indexed 2023-09-18T20:38:53Z
last_indexed 2023-09-18T20:38:53Z
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