Pharmaceutical application of solid dispersion technology in improving solubility of poorly soluble drugd : a review
Together with the permeability, the solubility of a drug plays an important role in determining its oral bioavailability. Nowadays, a majority of the new chemical entities are poorly water soluble candidates. For formulation scientists, it is a big deal to handle those drug candidates in order to fo...
Main Author: | Mandal, Uttam Kumar |
---|---|
Format: | Book Chapter |
Language: | English |
Published: |
IIUM Press
2011
|
Subjects: | |
Online Access: | http://irep.iium.edu.my/25605/ http://irep.iium.edu.my/25605/ http://irep.iium.edu.my/25605/1/CHAPTER_9%5B1%5D.pdf |
Similar Items
-
Polymer selection for nisoldipine solid dispersion to enhance solubility
by: Kyaw Oo, May, et al.
Published: (2015) -
Improved dissolution, flow property and compressibility of poor soluble API by co-grinding with fine silica
by: Chatterjee, Bappaditya
Published: (2017) -
Improved solubility of telmisartan by using freeze-dried solid dispersion method
by: Aljapairai, Khater Ahmed Saeed, et al.
Published: (2017) -
Polymeric behavior evaluation of PVP K30- poloxamer binary carrier for solid dispersed nisoldipine by experimental design
by: Kyaw Oo, May, et al.
Published: (2015) -
Evaluation of solvents’ effect on solubility, intermolecular interaction energies and habit of ascorbic acid crystals
by: Hassan, Syajaratul Jahriah, et al.
Published: (2019)