Histopathological evaluation of skin wound healing in rabbits treated by systemic dexamethasone

The present study was designed to evalurate the effect of dexamethasone on skin wound healing. Fifteen albino rabbits of 6.5 months age were used; an incision and suture was performed on the back skin of ten experimental rabbits previously treated with daily intramuscular injection of 2ml ampoule...

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Main Authors:	Kashmola, Muhanad Ali Hamdon, Al-Ani, Imad Matloub Dally, Mustafa, Nazih Shaban, Mustafa Al-Ahmad, Basma Ezzat
Format:	Article
Language:	English
Published:	Department of Anatomy, National University of Singapore 2012
Subjects:	QM Human anatomy QP Physiology RL Dermatology RM300 Drugs and their action
Online Access:	http://irep.iium.edu.my/24867/ http://irep.iium.edu.my/24867/ http://irep.iium.edu.my/24867/1/Skin_Wound_Healing.pdf

id	iium-24867
recordtype	eprints
spelling	iium-248672015-12-18T02:43:08Z http://irep.iium.edu.my/24867/ Histopathological evaluation of skin wound healing in rabbits treated by systemic dexamethasone Kashmola, Muhanad Ali Hamdon Al-Ani, Imad Matloub Dally Mustafa, Nazih Shaban Mustafa Al-Ahmad, Basma Ezzat QM Human anatomy QP Physiology RL Dermatology RM300 Drugs and their action The present study was designed to evalurate the effect of dexamethasone on skin wound healing. Fifteen albino rabbits of 6.5 months age were used; an incision and suture was performed on the back skin of ten experimental rabbits previously treated with daily intramuscular injection of 2ml ampoule containing 4 mg dexamethasone for one month and on fi ve control rabbits received 2ml normal saline for the same period. Biopsies of operated skin after 10 days of incision were processed for histopathological evaluation. Histological examination showed delay healing in experimental group in comparison to control group. It is concluded that prolonged use of dexamethasone or misuse of this drug suppress wound healing. Department of Anatomy, National University of Singapore 2012-04 Article PeerReviewed application/pdf en http://irep.iium.edu.my/24867/1/Skin_Wound_Healing.pdf Kashmola, Muhanad Ali Hamdon and Al-Ani, Imad Matloub Dally and Mustafa, Nazih Shaban and Mustafa Al-Ahmad, Basma Ezzat (2012) Histopathological evaluation of skin wound healing in rabbits treated by systemic dexamethasone. Annals of Microscopy, 12. pp. 27-33. ISSN 0219-2209 http://www.microscopy.org.sg/journal/vol_12/Annals%20of%20Microscopy%20Vol%2012-Web.pdf
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English
topic	QM Human anatomy QP Physiology RL Dermatology RM300 Drugs and their action
spellingShingle	QM Human anatomy QP Physiology RL Dermatology RM300 Drugs and their action Kashmola, Muhanad Ali Hamdon Al-Ani, Imad Matloub Dally Mustafa, Nazih Shaban Mustafa Al-Ahmad, Basma Ezzat Histopathological evaluation of skin wound healing in rabbits treated by systemic dexamethasone
description	The present study was designed to evalurate the effect of dexamethasone on skin wound healing. Fifteen albino rabbits of 6.5 months age were used; an incision and suture was performed on the back skin of ten experimental rabbits previously treated with daily intramuscular injection of 2ml ampoule containing 4 mg dexamethasone for one month and on fi ve control rabbits received 2ml normal saline for the same period. Biopsies of operated skin after 10 days of incision were processed for histopathological evaluation. Histological examination showed delay healing in experimental group in comparison to control group. It is concluded that prolonged use of dexamethasone or misuse of this drug suppress wound healing.
format	Article
author	Kashmola, Muhanad Ali Hamdon Al-Ani, Imad Matloub Dally Mustafa, Nazih Shaban Mustafa Al-Ahmad, Basma Ezzat
author_facet	Kashmola, Muhanad Ali Hamdon Al-Ani, Imad Matloub Dally Mustafa, Nazih Shaban Mustafa Al-Ahmad, Basma Ezzat
author_sort	Kashmola, Muhanad Ali Hamdon
title	Histopathological evaluation of skin wound healing in rabbits treated by systemic dexamethasone
title_short	Histopathological evaluation of skin wound healing in rabbits treated by systemic dexamethasone
title_full	Histopathological evaluation of skin wound healing in rabbits treated by systemic dexamethasone
title_fullStr	Histopathological evaluation of skin wound healing in rabbits treated by systemic dexamethasone
title_full_unstemmed	Histopathological evaluation of skin wound healing in rabbits treated by systemic dexamethasone
title_sort	histopathological evaluation of skin wound healing in rabbits treated by systemic dexamethasone
publisher	Department of Anatomy, National University of Singapore
publishDate	2012
url	http://irep.iium.edu.my/24867/ http://irep.iium.edu.my/24867/ http://irep.iium.edu.my/24867/1/Skin_Wound_Healing.pdf
first_indexed	2023-09-18T20:37:11Z
last_indexed	2023-09-18T20:37:11Z
_version_	1777409124431036416

Histopathological evaluation of skin wound healing in rabbits treated by systemic dexamethasone

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