The effect of chronic khat consumption on sperm count and motility in parent mice and their offspring

Khat is considered a psychoactive drug and has many side effects on different parts of the body organs. In this study the effects of khat on sperm count and motility in parent mice and their offspring were investigated. Animals were divided into two groups, Group 1 (khat group) contained twelve m...

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Main Authors: AlBadri, Cinaria Tarik, Al-Ani, Imad Matloub Dally, Hiba, Hassan Mohamed
Format: Article
Language:English
Published: EuroJournals Publishing, Inc. 2012
Subjects:
Online Access:http://irep.iium.edu.my/24866/
http://irep.iium.edu.my/24866/
http://irep.iium.edu.my/24866/1/Effect_of_Chronic_Khat_on_sperm_in_offspring.pdf
id iium-24866
recordtype eprints
spelling iium-248662015-12-18T02:44:52Z http://irep.iium.edu.my/24866/ The effect of chronic khat consumption on sperm count and motility in parent mice and their offspring AlBadri, Cinaria Tarik Al-Ani, Imad Matloub Dally Hiba, Hassan Mohamed QL Zoology QM Human anatomy QP Physiology Khat is considered a psychoactive drug and has many side effects on different parts of the body organs. In this study the effects of khat on sperm count and motility in parent mice and their offspring were investigated. Animals were divided into two groups, Group 1 (khat group) contained twelve male and twelve female mice, and they were given a daily dose of (50mg/kg) body weight khat extract by gastric gavage for four and eight weeks. Group 2 (control group) also contained twelve male and twelve female mice and received normal access of food and water. After four weeks of treatment, the males and females were allowed to mate and khat treatment continued for up to another four weeks. Twenty four male offspring from group 1 and group 2 were selected randomly and allowed to become mature. Male parent mice were killed at the 4th and 8th weeks of treatment, and their male offspring were killed when they reached maturity age (6-8weeks). Physiological examination of the sperm solution showed that there was a significant increase in sperm count and motility after 4 and 8 weeks of khat treatment, and in their adult offspring. Furthermore, histological changes were found in testicular sections of the adult male mice. EuroJournals Publishing, Inc. 2012 Article PeerReviewed application/pdf en http://irep.iium.edu.my/24866/1/Effect_of_Chronic_Khat_on_sperm_in_offspring.pdf AlBadri, Cinaria Tarik and Al-Ani, Imad Matloub Dally and Hiba, Hassan Mohamed (2012) The effect of chronic khat consumption on sperm count and motility in parent mice and their offspring. European Journal of Scientific Research, 69 (1). pp. 90-95. ISSN 1450-216X, 1450-202X http://www.europeanjournalofscientificresearch.com/ISSUES/EJSR_69_1_08.pdf
repository_type Digital Repository
institution_category Local University
institution International Islamic University Malaysia
building IIUM Repository
collection Online Access
language English
topic QL Zoology
QM Human anatomy
QP Physiology
spellingShingle QL Zoology
QM Human anatomy
QP Physiology
AlBadri, Cinaria Tarik
Al-Ani, Imad Matloub Dally
Hiba, Hassan Mohamed
The effect of chronic khat consumption on sperm count and motility in parent mice and their offspring
description Khat is considered a psychoactive drug and has many side effects on different parts of the body organs. In this study the effects of khat on sperm count and motility in parent mice and their offspring were investigated. Animals were divided into two groups, Group 1 (khat group) contained twelve male and twelve female mice, and they were given a daily dose of (50mg/kg) body weight khat extract by gastric gavage for four and eight weeks. Group 2 (control group) also contained twelve male and twelve female mice and received normal access of food and water. After four weeks of treatment, the males and females were allowed to mate and khat treatment continued for up to another four weeks. Twenty four male offspring from group 1 and group 2 were selected randomly and allowed to become mature. Male parent mice were killed at the 4th and 8th weeks of treatment, and their male offspring were killed when they reached maturity age (6-8weeks). Physiological examination of the sperm solution showed that there was a significant increase in sperm count and motility after 4 and 8 weeks of khat treatment, and in their adult offspring. Furthermore, histological changes were found in testicular sections of the adult male mice.
format Article
author AlBadri, Cinaria Tarik
Al-Ani, Imad Matloub Dally
Hiba, Hassan Mohamed
author_facet AlBadri, Cinaria Tarik
Al-Ani, Imad Matloub Dally
Hiba, Hassan Mohamed
author_sort AlBadri, Cinaria Tarik
title The effect of chronic khat consumption on sperm count and motility in parent mice and their offspring
title_short The effect of chronic khat consumption on sperm count and motility in parent mice and their offspring
title_full The effect of chronic khat consumption on sperm count and motility in parent mice and their offspring
title_fullStr The effect of chronic khat consumption on sperm count and motility in parent mice and their offspring
title_full_unstemmed The effect of chronic khat consumption on sperm count and motility in parent mice and their offspring
title_sort effect of chronic khat consumption on sperm count and motility in parent mice and their offspring
publisher EuroJournals Publishing, Inc.
publishDate 2012
url http://irep.iium.edu.my/24866/
http://irep.iium.edu.my/24866/
http://irep.iium.edu.my/24866/1/Effect_of_Chronic_Khat_on_sperm_in_offspring.pdf
first_indexed 2023-09-18T20:37:11Z
last_indexed 2023-09-18T20:37:11Z
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