Mammographic breast density : is there any association with positive family history of breast cancer?

INTRODUCTION: Breast cancer is the commonest overall cancer as well as the commonest cancer in women amongst all races. A higher incidence of breast cancer has been reported in women with dense breast parenchyma visible on mammogram and individuals with a family history of cancer. Previous study h...

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Main Authors:	Muhammed Nordin, Ellyda, Mohd Rus, Razman, Che Mohamed, Siti Kamariah, Hassan, Radhiana
Format:	Conference or Workshop Item
Language:	English
Published:	2012
Subjects:	R Medicine (General)
Online Access:	http://irep.iium.edu.my/23374/ http://irep.iium.edu.my/23374/ http://irep.iium.edu.my/23374/1/Poster_CoR_April__FINAL.pdf

id	iium-23374
recordtype	eprints
spelling	iium-233742012-08-08T03:27:21Z http://irep.iium.edu.my/23374/ Mammographic breast density : is there any association with positive family history of breast cancer? Muhammed Nordin, Ellyda Mohd Rus, Razman Che Mohamed, Siti Kamariah Hassan, Radhiana R Medicine (General) INTRODUCTION: Breast cancer is the commonest overall cancer as well as the commonest cancer in women amongst all races. A higher incidence of breast cancer has been reported in women with dense breast parenchyma visible on mammogram and individuals with a family history of cancer. Previous study has reported that women with a family history of breast cancer tend to have dense breasts and this partially explains their increased risk of breast cancer. OBJECTIVES: The aim of this study was to determine the distribution of mammographic density using Tabar classification and association between mammographic density and family history of breast cancer. METHODOLOGY: A retrospective review of data collected from women presenting for screening mammogram at IIUM Breast Centre from January 2008 until December 2009. A total of 506 subjects fulfilled the inclusion criteria. Both cranio-caudal and medio-lateral oblique views were reviewed on the BARCO monitor and the mammographic densities were classified by the interpreting radiologist, using Tabar’s classification system. Family history of breast cancer was defined as having at least one first degree relative (parent, sibling or child) with breast cancer. RESULTS: Out of 506 patients participated, 43.3% of the patients belong to Tabar pattern I; 19.6% Tabar pattern IV; 17.8% Tabar pattern II; 16.8% Tabar pattern III and 2.6% Tabar pattern V. Our result also revealed a significant association between mammographic density and positive family history of breast cancer (p= 0.006). CONCLUSION These results show the population variation in the percentage of dense tissue on mammography and women with higher breast density were more likely to have positive family history of breast cancer. Thus, the genetic factors that determine breast density may determine breast cancer risk. 2012-03-30 Conference or Workshop Item NonPeerReviewed application/pdf en http://irep.iium.edu.my/23374/1/Poster_CoR_April__FINAL.pdf Muhammed Nordin, Ellyda and Mohd Rus, Razman and Che Mohamed, Siti Kamariah and Hassan, Radhiana (2012) Mammographic breast density : is there any association with positive family history of breast cancer? In: College of Radiology Scientific Meeting 2012; Cancer Imaging, 30th March-1st April 2012, Equtorial Hotel, Penang. (Unpublished) http://www.ams.edu.sg/chapter/crs/2012%20ASM%20%281st%20Ann%29%20-%20Final.pdf
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English
topic	R Medicine (General)
spellingShingle	R Medicine (General) Muhammed Nordin, Ellyda Mohd Rus, Razman Che Mohamed, Siti Kamariah Hassan, Radhiana Mammographic breast density : is there any association with positive family history of breast cancer?
description	INTRODUCTION: Breast cancer is the commonest overall cancer as well as the commonest cancer in women amongst all races. A higher incidence of breast cancer has been reported in women with dense breast parenchyma visible on mammogram and individuals with a family history of cancer. Previous study has reported that women with a family history of breast cancer tend to have dense breasts and this partially explains their increased risk of breast cancer. OBJECTIVES: The aim of this study was to determine the distribution of mammographic density using Tabar classification and association between mammographic density and family history of breast cancer. METHODOLOGY: A retrospective review of data collected from women presenting for screening mammogram at IIUM Breast Centre from January 2008 until December 2009. A total of 506 subjects fulfilled the inclusion criteria. Both cranio-caudal and medio-lateral oblique views were reviewed on the BARCO monitor and the mammographic densities were classified by the interpreting radiologist, using Tabar’s classification system. Family history of breast cancer was defined as having at least one first degree relative (parent, sibling or child) with breast cancer. RESULTS: Out of 506 patients participated, 43.3% of the patients belong to Tabar pattern I; 19.6% Tabar pattern IV; 17.8% Tabar pattern II; 16.8% Tabar pattern III and 2.6% Tabar pattern V. Our result also revealed a significant association between mammographic density and positive family history of breast cancer (p= 0.006). CONCLUSION These results show the population variation in the percentage of dense tissue on mammography and women with higher breast density were more likely to have positive family history of breast cancer. Thus, the genetic factors that determine breast density may determine breast cancer risk.
format	Conference or Workshop Item
author	Muhammed Nordin, Ellyda Mohd Rus, Razman Che Mohamed, Siti Kamariah Hassan, Radhiana
author_facet	Muhammed Nordin, Ellyda Mohd Rus, Razman Che Mohamed, Siti Kamariah Hassan, Radhiana
author_sort	Muhammed Nordin, Ellyda
title	Mammographic breast density : is there any association with positive family history of breast cancer?
title_short	Mammographic breast density : is there any association with positive family history of breast cancer?
title_full	Mammographic breast density : is there any association with positive family history of breast cancer?
title_fullStr	Mammographic breast density : is there any association with positive family history of breast cancer?
title_full_unstemmed	Mammographic breast density : is there any association with positive family history of breast cancer?
title_sort	mammographic breast density : is there any association with positive family history of breast cancer?
publishDate	2012
url	http://irep.iium.edu.my/23374/ http://irep.iium.edu.my/23374/ http://irep.iium.edu.my/23374/1/Poster_CoR_April__FINAL.pdf
first_indexed	2023-09-18T20:35:24Z
last_indexed	2023-09-18T20:35:24Z
_version_	1777409011955531776

Mammographic breast density : is there any association with positive family history of breast cancer?

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