Antimicrobial activity and essential oils of Curcuma aeruginosa, Curcuma mangga, and Zingiber cassumunar from Malaysia

OBJECTIVE: To analyze the chemical composition of the essential oils of Curcuma aeruginosa (C. aeruginosa), Curcuma mangga (C. mangga), and Zingiber cassumunar (Z. cassumunar), and study their antimicrobial activity. METHODS: Essential oils obtained by steam distillation were analyzed by gas chro...

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Main Authors:	Tg Kamazeri, Tg Siti Amirah, Abd. Samah, Othman, Bakhtiar, M. Taher, Darnis, Deny Susanti, Qaralleh, Haitham
Format:	Article
Language:	English
Published:	Elsevier 2012
Subjects:	QR Microbiology
Online Access:	http://irep.iium.edu.my/23311/ http://irep.iium.edu.my/23311/ http://irep.iium.edu.my/23311/ http://irep.iium.edu.my/23311/1/Tg_Siti_Amirah_-_APJTM_Published_Article.pdf

id	iium-23311
recordtype	eprints
spelling	iium-233112012-05-16T01:29:46Z http://irep.iium.edu.my/23311/ Antimicrobial activity and essential oils of Curcuma aeruginosa, Curcuma mangga, and Zingiber cassumunar from Malaysia Tg Kamazeri, Tg Siti Amirah Abd. Samah, Othman Bakhtiar, M. Taher Darnis, Deny Susanti Qaralleh, Haitham QR Microbiology OBJECTIVE: To analyze the chemical composition of the essential oils of Curcuma aeruginosa (C. aeruginosa), Curcuma mangga (C. mangga), and Zingiber cassumunar (Z. cassumunar), and study their antimicrobial activity. METHODS: Essential oils obtained by steam distillation were analyzed by gas chromatography-mass spectrometry (GC-MS). The antimicrobial activity of the essential oils was evaluated against four bacteria: Bacillus cereus (B. cereus), Staphylococcus aureus (S. aureus), Escherichia coli (E. coli), and Pseudomonas aeruginosa (P. aeruginosa); and two fungi: Candida albicans (C. albicans) and Cyptococcus neoformans (C. neoformans), using disc-diffusion and broth microdilution methods. RESULTS: Cycloisolongifolene, 8,9-dehydro formyl (35.29%) and dihydrocostunolide (22.51%) were the major compounds in C. aeruginosa oil; whereas caryophyllene oxide (18.71%) and caryophyllene (12.69%) were the major compounds in C. mangga oil; and 2,6,9,9-tetramethyl-2,6,10-cycloundecatrien-1-one (60.77%) and α-caryophyllene (23.92%) were abundant in Z. cassumunar oil. The essential oils displayed varying degrees of antimicrobial activity against all tested microorganisms. C. mangga oil had the highest and most broad-spectrum activity by inhibiting all microorganisms tested, with C. neoformans being the most sensitive microorganism by having the lowest minimum inhibitory concentration (MIC) and minimum fungicidal concentration (MFC) values of 0.1 μL/mL. C. aeruginosa oil showed mild antimicrobial activity, whereas Z. cassumunar had very low or weak activity against the tested microorganisms. CONCLUSIONS: The preliminary results suggest promising antimicrobial properties of C. mangga and C. aeruginosa, which may be useful for food preservation, pharmaceutical treatment and natural therapies Elsevier 2012 Article PeerReviewed application/pdf en http://irep.iium.edu.my/23311/1/Tg_Siti_Amirah_-_APJTM_Published_Article.pdf Tg Kamazeri, Tg Siti Amirah and Abd. Samah, Othman and Bakhtiar, M. Taher and Darnis, Deny Susanti and Qaralleh, Haitham (2012) Antimicrobial activity and essential oils of Curcuma aeruginosa, Curcuma mangga, and Zingiber cassumunar from Malaysia. Asian Pacific Journal of Tropical Medicine, 5 (3). pp. 202-209. ISSN 1995-7645 http://dx.doi.org/10.1016/S1995-7645(12)60025-X doi:10.1016/S1995-7645(12)60025-X
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English
topic	QR Microbiology
spellingShingle	QR Microbiology Tg Kamazeri, Tg Siti Amirah Abd. Samah, Othman Bakhtiar, M. Taher Darnis, Deny Susanti Qaralleh, Haitham Antimicrobial activity and essential oils of Curcuma aeruginosa, Curcuma mangga, and Zingiber cassumunar from Malaysia
description	OBJECTIVE: To analyze the chemical composition of the essential oils of Curcuma aeruginosa (C. aeruginosa), Curcuma mangga (C. mangga), and Zingiber cassumunar (Z. cassumunar), and study their antimicrobial activity. METHODS: Essential oils obtained by steam distillation were analyzed by gas chromatography-mass spectrometry (GC-MS). The antimicrobial activity of the essential oils was evaluated against four bacteria: Bacillus cereus (B. cereus), Staphylococcus aureus (S. aureus), Escherichia coli (E. coli), and Pseudomonas aeruginosa (P. aeruginosa); and two fungi: Candida albicans (C. albicans) and Cyptococcus neoformans (C. neoformans), using disc-diffusion and broth microdilution methods. RESULTS: Cycloisolongifolene, 8,9-dehydro formyl (35.29%) and dihydrocostunolide (22.51%) were the major compounds in C. aeruginosa oil; whereas caryophyllene oxide (18.71%) and caryophyllene (12.69%) were the major compounds in C. mangga oil; and 2,6,9,9-tetramethyl-2,6,10-cycloundecatrien-1-one (60.77%) and α-caryophyllene (23.92%) were abundant in Z. cassumunar oil. The essential oils displayed varying degrees of antimicrobial activity against all tested microorganisms. C. mangga oil had the highest and most broad-spectrum activity by inhibiting all microorganisms tested, with C. neoformans being the most sensitive microorganism by having the lowest minimum inhibitory concentration (MIC) and minimum fungicidal concentration (MFC) values of 0.1 μL/mL. C. aeruginosa oil showed mild antimicrobial activity, whereas Z. cassumunar had very low or weak activity against the tested microorganisms. CONCLUSIONS: The preliminary results suggest promising antimicrobial properties of C. mangga and C. aeruginosa, which may be useful for food preservation, pharmaceutical treatment and natural therapies
format	Article
author	Tg Kamazeri, Tg Siti Amirah Abd. Samah, Othman Bakhtiar, M. Taher Darnis, Deny Susanti Qaralleh, Haitham
author_facet	Tg Kamazeri, Tg Siti Amirah Abd. Samah, Othman Bakhtiar, M. Taher Darnis, Deny Susanti Qaralleh, Haitham
author_sort	Tg Kamazeri, Tg Siti Amirah
title	Antimicrobial activity and essential oils of Curcuma aeruginosa, Curcuma mangga, and Zingiber cassumunar from Malaysia
title_short	Antimicrobial activity and essential oils of Curcuma aeruginosa, Curcuma mangga, and Zingiber cassumunar from Malaysia
title_full	Antimicrobial activity and essential oils of Curcuma aeruginosa, Curcuma mangga, and Zingiber cassumunar from Malaysia
title_fullStr	Antimicrobial activity and essential oils of Curcuma aeruginosa, Curcuma mangga, and Zingiber cassumunar from Malaysia
title_full_unstemmed	Antimicrobial activity and essential oils of Curcuma aeruginosa, Curcuma mangga, and Zingiber cassumunar from Malaysia
title_sort	antimicrobial activity and essential oils of curcuma aeruginosa, curcuma mangga, and zingiber cassumunar from malaysia
publisher	Elsevier
publishDate	2012
url	http://irep.iium.edu.my/23311/ http://irep.iium.edu.my/23311/ http://irep.iium.edu.my/23311/ http://irep.iium.edu.my/23311/1/Tg_Siti_Amirah_-_APJTM_Published_Article.pdf
first_indexed	2023-09-18T20:35:18Z
last_indexed	2023-09-18T20:35:18Z
_version_	1777409006127546368

Antimicrobial activity and essential oils of Curcuma aeruginosa, Curcuma mangga, and Zingiber cassumunar from Malaysia

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