Floating porous ceramics for high densiti cell culture in stirred bioreactors

Floating porous ceramics has been successfully developed using protein foaming-consolidation method. This method allows the control of porosity not only by the varied concentration of protein but also by managing the foaming process. Slurries of alumina powders and yolk was prepared by stirring...

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Main Authors:	Sopyan, Iis, Mel, Maizirwan, Fadli, Ahmad, Zulkifli, Nur Izzati
Format:	Conference or Workshop Item
Language:	English
Published:	2010
Subjects:	TP785 Clay industries. Ceramics. Glass. Cement industries
Online Access:	http://irep.iium.edu.my/23106/ http://irep.iium.edu.my/23106/ http://irep.iium.edu.my/23106/1/pp154.pdf

id	iium-23106
recordtype	eprints
spelling	iium-231062013-06-19T03:19:37Z http://irep.iium.edu.my/23106/ Floating porous ceramics for high densiti cell culture in stirred bioreactors Sopyan, Iis Mel, Maizirwan Fadli, Ahmad Zulkifli, Nur Izzati TP785 Clay industries. Ceramics. Glass. Cement industries Floating porous ceramics has been successfully developed using protein foaming-consolidation method. This method allows the control of porosity not only by the varied concentration of protein but also by managing the foaming process. Slurries of alumina powders and yolk was prepared by stirring the mixture and the resulting slip was poured into cylindrical shaped molds. Subsequently, they were subjected to drying for foaming and/or consolidation. Foaming process condition determined mean pore size and pore distribution. The dried green bodies of the samples were then burned to remove the pore creating agent followed by sintering at 1550°C for 2 h. Pore size distribution measurement showed that macropores of the sintered alumina porous bodies increased with the increased time and temperature of the drying process and were found in the range 50 - 800 μm. SEM measurement also confirmed this observation. Less foamed samples show lower shrinkage but higher compressive strength. A shrinkage of as low as 7.8% was observed for the sample dried at 110ºC but it increased significantly to 29.3% when dried at 180ºC. The compressive strength of the 110ºC's sample was 5.72 MPa at 43.6% porosity and it decreased to 4.57 MPa at 50.4% porosity when foamed at 180ºC. Density varied from 0.9 to 1.5 g/cm3 depending on the preparation condition. These results have opened a novel preparative way for porous ceramics especially alumina-based porous materials designed for biomedical applications such as cell culture in stirred bioreactor, drug delivery, bone implant etc. 2010 Conference or Workshop Item PeerReviewed application/pdf en http://irep.iium.edu.my/23106/1/pp154.pdf Sopyan, Iis and Mel, Maizirwan and Fadli, Ahmad and Zulkifli, Nur Izzati (2010) Floating porous ceramics for high densiti cell culture in stirred bioreactors. In: IIUM Research, Innovation & Invention Exhibition (IRIIE 2010), 26 - 27 January 2010, Kuala Lumpur. http://www.iium.edu.my/irie/10/
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English
topic	TP785 Clay industries. Ceramics. Glass. Cement industries
spellingShingle	TP785 Clay industries. Ceramics. Glass. Cement industries Sopyan, Iis Mel, Maizirwan Fadli, Ahmad Zulkifli, Nur Izzati Floating porous ceramics for high densiti cell culture in stirred bioreactors
description	Floating porous ceramics has been successfully developed using protein foaming-consolidation method. This method allows the control of porosity not only by the varied concentration of protein but also by managing the foaming process. Slurries of alumina powders and yolk was prepared by stirring the mixture and the resulting slip was poured into cylindrical shaped molds. Subsequently, they were subjected to drying for foaming and/or consolidation. Foaming process condition determined mean pore size and pore distribution. The dried green bodies of the samples were then burned to remove the pore creating agent followed by sintering at 1550°C for 2 h. Pore size distribution measurement showed that macropores of the sintered alumina porous bodies increased with the increased time and temperature of the drying process and were found in the range 50 - 800 μm. SEM measurement also confirmed this observation. Less foamed samples show lower shrinkage but higher compressive strength. A shrinkage of as low as 7.8% was observed for the sample dried at 110ºC but it increased significantly to 29.3% when dried at 180ºC. The compressive strength of the 110ºC's sample was 5.72 MPa at 43.6% porosity and it decreased to 4.57 MPa at 50.4% porosity when foamed at 180ºC. Density varied from 0.9 to 1.5 g/cm3 depending on the preparation condition. These results have opened a novel preparative way for porous ceramics especially alumina-based porous materials designed for biomedical applications such as cell culture in stirred bioreactor, drug delivery, bone implant etc.
format	Conference or Workshop Item
author	Sopyan, Iis Mel, Maizirwan Fadli, Ahmad Zulkifli, Nur Izzati
author_facet	Sopyan, Iis Mel, Maizirwan Fadli, Ahmad Zulkifli, Nur Izzati
author_sort	Sopyan, Iis
title	Floating porous ceramics for high densiti cell culture in stirred bioreactors
title_short	Floating porous ceramics for high densiti cell culture in stirred bioreactors
title_full	Floating porous ceramics for high densiti cell culture in stirred bioreactors
title_fullStr	Floating porous ceramics for high densiti cell culture in stirred bioreactors
title_full_unstemmed	Floating porous ceramics for high densiti cell culture in stirred bioreactors
title_sort	floating porous ceramics for high densiti cell culture in stirred bioreactors
publishDate	2010
url	http://irep.iium.edu.my/23106/ http://irep.iium.edu.my/23106/ http://irep.iium.edu.my/23106/1/pp154.pdf
first_indexed	2023-09-18T20:35:02Z
last_indexed	2023-09-18T20:35:02Z
_version_	1777408988494692352

Floating porous ceramics for high densiti cell culture in stirred bioreactors

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