Fabrication of porous ceramic scaffolds via polymeric sponge method using sol-gel derived strontium doped hydroxyapatite powder
Recently, development of porous calcium phosphates ceramics have raised considerable interest. A porous structure promotes cell attachment, proliferation and provides pathways for biofluids. Therefore, a high porosity with interconnected pore structure generally favors tissue regeneration. In t...
| Main Authors: | , , |
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| Format: | Conference or Workshop Item |
| Language: | English |
| Published: |
2011
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| Subjects: | |
| Online Access: | http://irep.iium.edu.my/21781/ http://irep.iium.edu.my/21781/1/Fabrication_of_porous_ceramic_scaffolds_via_polymeric_sponge_method_using_sol-gel_derived_strontium_doped_hydroxyapatite_powder.pdf |
| Summary: | Recently, development of porous calcium
phosphates ceramics have raised considerable interest. A
porous structure promotes cell attachment, proliferation and
provides pathways for biofluids. Therefore, a high porosity
with interconnected pore structure generally favors tissue
regeneration. In this work, replication of 0, 2, 5, 10 and 15%
SrHA (strontium-doped hydroxyapatite) porous scaffolds via
polymeric sponge method has been employed using the sol-gel
derived SrHA powders. To prepare the porous samples, the
synthesized SrHA powders was mixed with distilled water and
appropriate amount of dispersing agent followed by drying in
the ambient air and specific sintering process. Morphological
evaluation by FESEM measurement revealed that the SrHA
scaffolds were characterized by macro-micro interconnected
porosity, which replicates the morphology of the cancellous
bone. Compression test on the porous scaffolds revealed that
doping 10 mol% of strontium in HA has increased the
compressive strength by a factor of two compared to the
undoped HA with 1.81±0.26 MPa at 41% porosity. |
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