Determination of octanol-water partition coefficients of anti-microbial alkaloids from Glycosmis pentaphylla (Retz) DC

Octanol-water partition coefficient (KOW) values of anti-microbial alkaloids, arborine and arborinine of Glycosmis pentaphylla (Retz) DC were determined. The method of extraction by solvents of these alkaloids and the following isolation procedures using column chromatography techniques will adopt t...

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Main Authors:	Ahmad, Kausar, Mohd. Hassan, Norazian, Helaluddin , Abul Bashar Mohammed, Mat Ali, Idura, Mansor, Norhafizah
Format:	Conference or Workshop Item
Language:	English
Published:	2010
Subjects:	R Medicine (General) RB Pathology
Online Access:	http://irep.iium.edu.my/21201/ http://irep.iium.edu.my/21201/ http://irep.iium.edu.my/21201/1/Detrmination_of_octanol-water.pdf

id	iium-21201
recordtype	eprints
spelling	iium-212012013-07-17T01:17:25Z http://irep.iium.edu.my/21201/ Determination of octanol-water partition coefficients of anti-microbial alkaloids from Glycosmis pentaphylla (Retz) DC Ahmad, Kausar Mohd. Hassan, Norazian Helaluddin , Abul Bashar Mohammed Mat Ali, Idura Mansor, Norhafizah R Medicine (General) RB Pathology Octanol-water partition coefficient (KOW) values of anti-microbial alkaloids, arborine and arborinine of Glycosmis pentaphylla (Retz) DC were determined. The method of extraction by solvents of these alkaloids and the following isolation procedures using column chromatography techniques will adopt those ascertained and established earlier (Norazian, 2006). A shake-flask method was used to determine the octanol-water partition coefficients from (298.15, 303.15, 308.15 and 313.15)k. Each compound was dissolved in the octanol to a known concentration and placed in octanol-water system and allowed to equilibrate. The concentration in the octanol phase was then determined by using spectrophotometer. The KOW was calculated as the ratio of the concentration in octanol phase to the concentration in aqueous phase. 2010 Conference or Workshop Item NonPeerReviewed application/pdf en http://irep.iium.edu.my/21201/1/Detrmination_of_octanol-water.pdf Ahmad, Kausar and Mohd. Hassan, Norazian and Helaluddin , Abul Bashar Mohammed and Mat Ali, Idura and Mansor, Norhafizah (2010) Determination of octanol-water partition coefficients of anti-microbial alkaloids from Glycosmis pentaphylla (Retz) DC. In: 3rd International Conference on Advancement in Science and Technology (iCAST) 2010, 27-29 November 2010, Vistana Hotel, Kuantan, Pahang. http://www.iium.edu.my/icast/2010/index.php?option=com_content&view=article&id=14&Itemid=17
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English
topic	R Medicine (General) RB Pathology
spellingShingle	R Medicine (General) RB Pathology Ahmad, Kausar Mohd. Hassan, Norazian Helaluddin , Abul Bashar Mohammed Mat Ali, Idura Mansor, Norhafizah Determination of octanol-water partition coefficients of anti-microbial alkaloids from Glycosmis pentaphylla (Retz) DC
description	Octanol-water partition coefficient (KOW) values of anti-microbial alkaloids, arborine and arborinine of Glycosmis pentaphylla (Retz) DC were determined. The method of extraction by solvents of these alkaloids and the following isolation procedures using column chromatography techniques will adopt those ascertained and established earlier (Norazian, 2006). A shake-flask method was used to determine the octanol-water partition coefficients from (298.15, 303.15, 308.15 and 313.15)k. Each compound was dissolved in the octanol to a known concentration and placed in octanol-water system and allowed to equilibrate. The concentration in the octanol phase was then determined by using spectrophotometer. The KOW was calculated as the ratio of the concentration in octanol phase to the concentration in aqueous phase.
format	Conference or Workshop Item
author	Ahmad, Kausar Mohd. Hassan, Norazian Helaluddin , Abul Bashar Mohammed Mat Ali, Idura Mansor, Norhafizah
author_facet	Ahmad, Kausar Mohd. Hassan, Norazian Helaluddin , Abul Bashar Mohammed Mat Ali, Idura Mansor, Norhafizah
author_sort	Ahmad, Kausar
title	Determination of octanol-water partition coefficients of anti-microbial alkaloids from Glycosmis pentaphylla (Retz) DC
title_short	Determination of octanol-water partition coefficients of anti-microbial alkaloids from Glycosmis pentaphylla (Retz) DC
title_full	Determination of octanol-water partition coefficients of anti-microbial alkaloids from Glycosmis pentaphylla (Retz) DC
title_fullStr	Determination of octanol-water partition coefficients of anti-microbial alkaloids from Glycosmis pentaphylla (Retz) DC
title_full_unstemmed	Determination of octanol-water partition coefficients of anti-microbial alkaloids from Glycosmis pentaphylla (Retz) DC
title_sort	determination of octanol-water partition coefficients of anti-microbial alkaloids from glycosmis pentaphylla (retz) dc
publishDate	2010
url	http://irep.iium.edu.my/21201/ http://irep.iium.edu.my/21201/ http://irep.iium.edu.my/21201/1/Detrmination_of_octanol-water.pdf
first_indexed	2023-09-18T20:32:07Z
last_indexed	2023-09-18T20:32:07Z
_version_	1777408805563269120

Determination of octanol-water partition coefficients of anti-microbial alkaloids from Glycosmis pentaphylla (Retz) DC

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